Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Unraveling the luminescence secrets of turquoise nucleus cultivated pearls. [PDF]
Li Y, Su Q, Shao W, Li L.
europepmc +1 more source
We report a high‐dipole interlayer, MQPPO, that simultaneously improves efficiency and stability in perovskite solar cells. Its strong interfacial dipole enhances photovoltaic performance, while its uniform coverage and strong interaction with Ag effectively suppress AgI formation, ensuring long‐term stability under moisture and thermal stress.
Dong Hyun Lee +11 more
wiley +1 more source
Clinical performance of low-shrinkage giomer compared to nanohybrid resin composite in proximal restorations after one year: a randomized clinical trial. [PDF]
AbdelHafez MI, Shaalan O, Hamza H.
europepmc +1 more source
Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei +7 more
wiley +1 more source
24-month randomized controlled clinical trial assessment of surface texture, color stability, and marginal discoloration of sonic activated bulk-fill resin composite according to USPHS and FDI criteria. [PDF]
Aref A, Abd-Elhakim S, Riad M.
europepmc +1 more source
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang +15 more
wiley +1 more source
A Cross-Sectional Study of Acceptability and Influence of HEALing Communities Study Communications Campaign Messaging Among Community Members in Four U.S. States. [PDF]
Luster J +10 more
europepmc +1 more source
A speckle correlation centroid localization method (SCCLM) is proposed for non‐invasive tracking of an arbitrary deformable object through scattering media and around corners, requiring no prior information. Its effectiveness is demonstrated not only in tracking hidden objects beyond the memory effect region but also in following objects undergoing ...
Aiping Zhai +6 more
wiley +1 more source
Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth. [PDF]
Zhou Y +6 more
europepmc +1 more source

