Prospective, randomized, paired-comparison clinical trial of a new universal adhesive in posterior composite restorations: A 2-year evaluation. [PDF]
Perdigão J +5 more
europepmc +1 more source
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin +9 more
wiley +1 more source
Emergency department overcrowding: first Swiss application of the Emergency Department Work Index and risk factors for overcrowding. [PDF]
Herzog A +3 more
europepmc +1 more source
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
Revision of the genus <i>Labidolanguria</i> Fowler, 1908 (Coleoptera, Erotylidae, Languriinae), with descriptions of a new species and two new combinations. [PDF]
Huang ZZ, Yang XK, Ge SQ.
europepmc +1 more source
Photonuclear Population of 229m,gTh in Th‐Doped Crystals Toward Nuclear Clock Development
This study demonstrates a novel photonuclear approach for producing the nuclear clock isomer 229mTh in thorium‐doped crystals, overcoming current supply limitations. Through cross‐section calculations and Monte Carlo simulations, we identify optimal crystal materials and irradiation conditions, achieving high signal‐to‐noise ratios.
Hao‐Yang Lan +9 more
wiley +1 more source
Viral Infection and the Blood-Brain Barrier: Molecular Research Insights and Therapies. [PDF]
Boardman SA +14 more
europepmc +1 more source
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang +7 more
wiley +1 more source
The Effects of Question Prompts and Worked Examples on Primary School Students' Scientific Achievement, Argumentation Skills, Motivation, and Cognitive Load. [PDF]
Xu C, Zhu J, Wang Y, Zheng Y.
europepmc +1 more source

