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ABSTRACT Background Androgen deprivation therapy (ADT) increases the risk of adverse cardiovascular events in patients with prostate cancer. ADT can induce body composition change; however, the association between body composition change and cardiovascular outcomes remains unclear.
Jie Lee+7 more
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ESC Heart Failure, Volume 12, Issue 3, Page 2371-2376, June 2025.
Ying Wang+7 more
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STEROID PRIMING OF THE LUTEINIZING HORMONE RESPONSE TO LUTEINIZING HORMONE RELEASING HORMONE
Journal of Endocrinology, 1978Perifusion experiments were performed to study the stimulatory effects of luteinizing hormone releasing hormone (LH-RH) on the release of LH from anterior pituitary tissue. Exposure of pituitary tissue from normal male rats to LH-RH (5 ng/ml for 5 min) induced a small release of LH; in tissue from ovariectomized rats receiving no pretreatment, the ...
L. V. Beck+4 more
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Luteinizing Hormone Estimation
Endocrine Research, 2004Luteinizing hormone (LH) is an important hormone of the reproductive system, which has found application in diagnosis and therapeutic medicine. It plays a vital role in the development and functioning of the reproductive system. Determination of LH concentration is important for detection of dysfunction of the pituitary-ovarian axis, diagnosis of ...
Atul N. Jadhav+2 more
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Chemischer Informationsdienst, 1975
Two varients of LH-RH, less than Glu-D-Phe-Trp-D-Ala-Leu-Arg-Pro-Gly-NH2 (I) and less than Glu-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHCH2CH3 (II), have been synthesized by solid-phase methods. Both peptides strongly inhibit the LH-RH induced secretion of LH in an in vitro assay; however, only I proved effective in preventing ovulation in the 4-day ...
John P. Yardley+3 more
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Two varients of LH-RH, less than Glu-D-Phe-Trp-D-Ala-Leu-Arg-Pro-Gly-NH2 (I) and less than Glu-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHCH2CH3 (II), have been synthesized by solid-phase methods. Both peptides strongly inhibit the LH-RH induced secretion of LH in an in vitro assay; however, only I proved effective in preventing ovulation in the 4-day ...
John P. Yardley+3 more
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Domestic Animal Endocrinology, 1992
The secretion of luteinizing hormone-releasing hormone (LHRH) and its temporal association with pulses of luteinizing hormone (LH) was examined in ovariectomized prepuberal gilts. Push-pull cannulae (PPC) were implanted within the anterior pituitary gland and LHRH was quantified from 10 min (200 microliters) perfusate samples.
George B. Rampacek+3 more
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The secretion of luteinizing hormone-releasing hormone (LHRH) and its temporal association with pulses of luteinizing hormone (LH) was examined in ovariectomized prepuberal gilts. Push-pull cannulae (PPC) were implanted within the anterior pituitary gland and LHRH was quantified from 10 min (200 microliters) perfusate samples.
George B. Rampacek+3 more
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THE LUTEINIZING HORMONE RECEPTOR
Annual Review of Physiology, 1995▪ Abstract The luteinizing hormone receptor (LHR) is a member of the subfamily of glycoprotein hormone receptors within the superfamily of G protein–coupled receptor (GPCR)/seven-transmembrane domain receptors. Over the past eight years, major advances have been made in determining the structure and function of the LHR and its gene.
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Mechanism of Action of Luteinizing Hormone
Nature, 1970WE have reported1 studies on luteinized rat ovary in which we found that an approximate doubling of the rate of steroid synthesis following stimulation with luteinizing hormone was not associated with any change in the tissue NADPH/NADP+ concentration ratio.
A. P. F. Flint, Richard M. Denton
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Luteinizing Hormone-Releasing Hormone
Archives of Internal Medicine, 1986To the Editor. —In their excellent review of gonadotropin-releasing hormone (GnRH) (also known as luteinizing hormone-releasing hormone [LH-RH]) in the September 1985 issue of theArchives, Hammond and Ory 1 cite the potential advantages of GnRH over conventional gonadotropin therapy for induction of spermatogenesis as rapidity, higher success rate ...
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Luteinizing-Hormone-Releasing Hormone
New England Journal of Medicine, 1977One of the exciting advances in endocrinology has been the discovery of a family of peptidic neurohormones in the hypothalamus that stimulate or inhibit the secretion of adenohypophysial hormones.
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