Results 121 to 130 of about 71,128 (264)
Homo sapiens, industrialisation and the environmental mismatch hypothesis
Biological Reviews, EarlyView.ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
Continuous use of gonadotropin-releasing hormone (GnRH)-agonist maintains high luteinizing hormone concentrations at the time of oocyte retrieval in women undergoing GnRH-agonist long protocol assisted reproductive technology treatment and stimulation with recombinant follicle-stimulating hormone [PDF]
, 2009 Shirei Ohgi +5 more
openalex
Clinical Endocrinology, EarlyView.ABSTRACT Objective and Background Early identification of adrenal insufficiency (AI) during immune‐checkpoint inhibitors (ICIs) is crucial to prevent life‐threatening consequences; however, the diagnosis is challenging. Design, Patients and Measurement In this prospective observational study, ICI‐treated cancer patients with morning serum cortisol (SC)
Alice Nervo +6 more
wiley +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Introduction Urinary gonadotropins measurement is a noninvasive method for evaluation of pubertal development and may have utility in population studies. Objectives To investigate the utility of urinary gonadotropins as a noninvasive biomarker of puberty in boys and girls.
Alexander Spiers +5 more
wiley +1 more source
Kainate Receptor Subunit-Positive Gonadotropin-Releasing Hormone Neurons Express c-Fos during the Steroid-Induced Luteinizing Hormone Surge in the Female Rat1 [PDF]
, 2000 Özhan Eyigör, Lothar Jennes
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Clinical Endocrinology, EarlyView.ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri +6 more
wiley +1 more source
Certain Activating Mutations within Helix 6 of the Human Luteinizing Hormone Receptor May Be Explained by Alterations That Allow Transmembrane Regions to Activate Gs [PDF]
, 1998 Amy N. Abell +2 more
openalex +1 more source
Cell Proliferation, EarlyView.Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source