Results 121 to 130 of about 447,250 (290)

Feminizing Therapy in People With Klinefelter Syndrome and Gender Incongruence: Considerations for Treatment Without Testosterone Blockers

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS; 47, XXY) usually involves male sex development and gender identity. Small studies suggest gender incongruence may be more common in KS, but feminizing gender‑affirming hormone therapy in this group has been scarcely reported.
Maaike Kroon, Tamira Klaziene Klooker, Sabine Elisabeth Hannema, Martin Den Heijer   +3 more
wiley   +1 more source

Luteinizing hormone-releasing hormone receptor antagonist may reduce postmenopausal flushing

, 2012
Item does not contain fulltextOBJECTIVE: Hormone therapy (HT) is the most effective treatment of postmenopausal (PMP) flushing; however, its use is often contraindicated.
Filius, M., Bancsi, L., Boer, H. de, Gastel, P. van, Darryl Telting, Moniek van der Zanden, Telting, D., Margreet Filius, Hans de Boer, Zanden, M. van der, Petri van Gastel, Laszlo Bancsi   +11 more
core   +1 more source

Machine Learning‐Based Prediction of Sperm Retrieval Outcomes in Patients With Klinefelter Syndrome: A Multicenter Study With External Validation

Andrology, EarlyView.
ABSTRACT Background The Klinefelter syndrome is a common genetic cause of male infertility, and testicular sperm extraction (TESE) enables sperm retrieval in a subset of affected patients. However, predicting TESE success remains challenging due to the heterogeneous clinical and endocrinological presentation of the Klinefelter syndrome.
Murat Gül, Ali Şahin, Cevahir Özer, Mesut Altan, Tansu Güdelci, Kadir Can Sahin, Mehmet Hamza Gültekin, Muhammed Arif İbis, Mesut Berkan Duran, Burak Sivaslıoğlu, Eray Hasırcı, Mert Kılıç, Ali Can Albaz, Gökhan Çeker, Gianmaria Salvio   +14 more
wiley   +1 more source

The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari, Leonardo Dalla Valentina, Cristina Felicani, Filippo Gabrielli, Simonetta Lugari, Giovanni Corona, Paolo Ventura, Manuela Simoni, Fabio Nascimbeni, Daniele Santi   +9 more
wiley   +1 more source

Suppression of ovulation in the rat by an orally active antagonist of luteinizing hormone-releasing hormone

, 1982
A synthetic antagonist of luteinizing hormone-releasing hormone blocked ovulation in rats in a dose-dependent manner when given by gavage on the afternoon of proestrus.
Horvath, A, Coy, D H, Nekola, M B, Ge, L J, Schally, A V   +4 more
core   +1 more source

Sex Steroids Measurement by Mass Spectrometry in Hypogonadal Men in a Real‐World Setting: Serum Estradiol (E2) and E2 to Total Testosterone Ratio Do Not Differ Between Patients With Klinefelter Syndrome and Non‐Klinefelter Syndrome Hypogonadism

Andrology, EarlyView.
ABSTRACT Background Traditionally, Klinefelter syndrome (KS) was considered a clinical condition associated with hyperestrogenism. Aim To compare circulating sex steroids, particularly estrogens, in a cohort of KS and non‐KS hypogonadal men. Materials and Methods A cohort of hypogonadal men, treated and untreated, was prospectively enrolled in a real ...
Daniele Renda Livraghi, Francesco Costantino, Filippo Vignali, Giulia Canu, Maria Cristina De Santis, Laura Roli, Tommaso Fasano, Vincenzo Rochira, Sara De Vincentis   +8 more
wiley   +1 more source

Maternal Consumption of Artificially Sweetened Beverages in Pregnancies and Biomarkers of Fecundity in Adult Sons

Andrology, EarlyView.
ABSTRACT Introduction Maternal intake of artificial sweeteners in beverages (ASB) during pregnancy may have a programming effect on offspring health, including biomarkers of male fecundity. Objective We investigated whether maternal intake of ASB during pregnancy was associated with biomarkers of male fecundity in adult sons.
Frida Vinther Hauberg, Emilie Marquart Hviid, Mette Viola Stokholm, Anne Gaml‐Sørensen, Anne Ahrendt Bjerregaard, Thorhallur I. Halldorsson, Sandra Søgaard Tøttenborg, Cecilia Høst Ramlau‐Hansen   +7 more
wiley   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Mapping of the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) to chicken chromosome 3

, 2001
Source/description: The chicken luteinizing hormone/choriogonadotropin receptor gene has been cloned and sequenced. To produce markers for linkage mapping genomic DNA sequence from exon 7 to exon 9 including the intervening introns and exon was cloned ...
Romanov, MN, Ge, S F, Romanov, Michael N, Paton, IR, Paton, Ian R, I. C. Dunn, Ge, SF, M. N. Romanov, Sharp, P J, Sharp, PJ, Dunn, Ian C., Burt, DW, S. F. Ge, P. J. Sharp, D. W. Burt, Burt, David W, Dunn, IC, I. R. Paton   +17 more
core   +1 more source

Obesity Is an Independent Risk Factor for Oligozoospermia, With Co‐Existing Hyperglycemia Exacerbating Risks of Asthenozoospermia and Elevated Sperm DNA Fragmentation

Andrology, EarlyView.
ABSTRACT Background Metabolic health plays a critical role in maintaining male fertility and may influence offspring health. Therefore, it is necessary to incorporate metabolic indicators into the clinical assessment of male fertility. However, the relationships between different metabolic abnormalities and semen quality remain incompletely understood.
Rubing Hu, Haijiao Zou, Qiaodan Li, Weihong Fan, Jian Xu   +4 more
wiley   +1 more source