A Cross‐Sectional Study Reveals Hormonal Signatures of Smoking‐Related Infertility
ABSTRACT Cigarette smoking remains a common modifiable lifestyle risk factor for male infertility, yet the exact mechanisms linking smoking to overall fertility decline are not fully understood. This study investigates how smoking affects sperm quality deterioration and examines the potential role of hormonal pathways in mediating these effects. Robust
Birupakshya Paul Choudhury +9 more
wiley +1 more source
Recombinant Follicle-Stimulating Hormone and Luteinizing Hormone Enhance Mitochondrial Function and Metabolism in Aging Female Reproductive Cells. [PDF]
Lin LT, Li CJ, Lee YS, Tsui KH.
europepmc +1 more source
ABSTRACT Aim Aetiological factors affecting the phenotype of adrenarche are largely unknown. This study investigated the phenotypic variability of premature adrenarche. Methods In this cross‐sectional retrospective registry study, data on 91 mainly Caucasian children diagnosed with premature adrenarche were retrieved from patient records.
Eetu Kanniainen +2 more
wiley +1 more source
Comparative Analysis of Commercial Immunoassays for the Determination of Total, Intact, and Nonintact Luteinizing Hormone in Urine. [PDF]
Demir A +4 more
europepmc +1 more source
Preferences between three options for androgen deprivation therapy: a focus group study
Objectives Androgen deprivation therapy (ADT) forms the mainstay of treatment for advanced prostate cancer. Traditionally administered as a luteinising hormone‐releasing hormone (LHRH) agonist depot injection, newer options for ADT include transdermal oestradiol patches (tE2) or oral LHRH antagonists.
Hannah L. Rush +13 more
wiley +1 more source
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy +5 more
wiley +1 more source
Vaginal micronized progesterone on preventing luteinizing hormone untimely surge in ART cycles: A prospective proof-of-concept study. [PDF]
Souza MDCB +6 more
europepmc +1 more source
ABSTRACT Objective Oral estrogens increase the levels of cortisol binding globulin (CBG) potentially affecting test results for adrenal insufficiency. The objective was to evaluate the influence of oral and transdermal estradiol on total plasma (p) and salivary cortisol in hypogonadal women with secondary adrenal insufficiency or at risk of developing ...
Laura S. Aagaard +4 more
wiley +1 more source
A retrospective cohort study assessing medication coverage in patients with prostate cancer prescribed luteinizing hormone releasing hormone (LHRH) agonists in England. [PDF]
Sayers I +8 more
europepmc +1 more source
The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source

