Results 51 to 60 of about 127,194 (360)

Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice. [PDF]

open access: yes, 2015
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes.
Coss, Djurdjica   +3 more
core   +1 more source

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

open access: yesAdvanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song   +11 more
wiley   +1 more source

Association of the genetic variants of luteinizing hormone, luteinizing hormone receptor and polycystic ovary syndrome

open access: yesReproductive Biology and Endocrinology, 2012
Background High circulating luteinizing hormone (LH) level is a typical biochemical feature of polycystic ovary syndrome (PCOS) whose pathophysiology is still unclear.
Liu Nana   +7 more
doaj   +1 more source

Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice

open access: yeseLife, 2020
The gonadotropin-releasing hormone (GnRH) neurons exhibit pulse and surge modes of activity to control fertility. They also exhibit an unusual bipolar morphology comprised of a classical soma-proximal dendritic zone and an elongated secretory process ...
Li Wang   +8 more
doaj   +1 more source

Relationship between Body Mass Index and Bone Turnover Markers in Girls with Idiopathic Central Precocious Puberty

open access: yesInternational Journal of Clinical Practice, 2023
Background. This study aimed to determine the effect of body mass index (BMI) on bone turnover markers in girls with idiopathic central precocious puberty (ICPP) according to weight status at diagnosis. Methods.
Jing Zhang   +5 more
doaj   +1 more source

Spermatogenesis Duration on Adult Javan Langur (Trachypithecus auratus) Based on Testosteron Hormone and Luteinizing Hormone (LH)

open access: yesJurnal Medik Veteriner, 2021
This study aimed to determine the duration of the process of spermatogenesis in adult Javan langurs (Trachypithecus auratus) by measuring levels of the hormone testosterone and luteinizing hormone (LH), as one of the efforts to increase the success of ...
Olea Rody Sangen   +3 more
doaj   +1 more source

Species-specific differences in follicular antral sizes result from diffusion-based limitations on the thickness of the granulosa cell layer

open access: yes, 2013
The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte.
Bächler, M.   +3 more
core   +1 more source

Erythema nodosum as a result of estrogen patch therapy for prostate cancer: a case report. [PDF]

open access: yes, 2015
© 2015 Coyle et al.Introduction: Erythema nodosum is often associated with a distressing symptomatology, including painful subcutaneous nodules, polyarthropathy, and significant fatigue.
Abel, P   +3 more
core   +2 more sources

Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL‐Related Disorders: A Cross‐Sectional Caregiver Survey Analysis

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring   +4 more
wiley   +1 more source

Success Rates of Clomiphene Citrate and Recombinant Gonadotropin Cycles: A Single-Center Experience

open access: yesGynecology Obstetrics & Reproductive Medicine, 2020
Objective: This aim of this study is to assess the ovulation induction cycles based on clomiphene citrate and gonadotropin administration and specify the factors associated with successful outcomes.
Beril Gurlek   +5 more
doaj   +1 more source

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