Results 51 to 60 of about 447,250 (290)

Creatinine–Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib

Clinical Pharmacology &Therapeutics, EarlyView.
Abemaciclib increases serum creatinine by inhibiting renal tubular transporters rather than reducing true glomerular filtration rate, a phenomenon known as pseudo‐acute kidney injury. Creatinine–cystatin C discrepancy and genetic determinants of this elevation remain insufficiently characterized in Japanese patients.
Hiroaki Watanabe, Keita Hirai, Takaaki Oba, Mayu Ono, Ken‐ichi Ito, Takafumi Naito   +5 more
wiley   +1 more source

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

Food Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad, Medhat Ibrahim A. Omar, Mohammed I. Elkhateeb, Ahmed A. Zaky   +3 more
wiley   +1 more source

Assessment of hormonal activity in patients with premature ejaculation

International Brazilian Journal of Urology
Purpose Premature ejaculation is considered the most common type of male sexual dysfunction. Hormonal controls of ejaculation have not been exactly elucidated. The aim of our study is to investigate the role of hormonal factors in patients with premature
Lütfi Canat, Akif Erbin, Masum Canat, Mehmet Dinek, Turhan Çaşkurlu   +4 more
doaj   +1 more source

Effects of Selective Serotonin Reuptake Inhibitor Treatment on Ovarian Reserves in Patients with Depression

Medicina, 2023
Background and Objectives: The goal of this study was to investigate the effect of selective serotonin reuptake inhibitor treatment on the ovarian reserves of women of reproductive age with major depressive disorder.
Soner Gök, Berfin Can Gök, Erkan Alataş, Hande Senol, Osman Zülkif Topak   +4 more
doaj   +1 more source

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source

Correlation between anti-Mullerian hormone, luteinizing hormone, follicle-stimulating hormone, thyroid-stimulating hormone, estradiol, and vitamin D: a retrospective study in women with secondary infertility

Novelty in Biomedicine
Background: This study aims to evaluate the correlation between anti-Müllerian hormone, luteinizing hormone, follicle-stimulating hormone, thyroid-stimulating hormone, Estradiol, and vitamin D in women experiencing secondary infertility.
Zahra Moradi Ghadi, Elham Saffarieh, Maryam Ezzedin, Behpoor Yousefi, Azam Azargoon, Abbas Ziari, Najme Hemmatian, Nahid Azad   +7 more
doaj   +1 more source

On the function of arginine in luteinizing hormone‐releasing hormone [PDF]

FEBS Letters, 1977
Many analogs of luteinizing hormone-releasing hormone (LH-RH) have been recently synthesized in order to investigate the significance of the various constituent amino acids in hormonal activity [ 1 ] . Assessments of the capacity of analogs to stimulate release of LH and FSH have revealed that arginine in position 8 on the peptide chain is critical for
Hazum, E., Fridkin, M., Meidan, R., Koch, Y.   +3 more
openaire   +2 more sources

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari, Melis Pehlivantürk Kizilkan, Musa Öztürk, İlker Ertuğrul, Hayrettin Hakan Aykan, Tevfik Karagöz, Nuray Kanbur, Orhan Derman, Sinem Akgül   +8 more
wiley   +1 more source

Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice

eLife, 2020
The gonadotropin-releasing hormone (GnRH) neurons exhibit pulse and surge modes of activity to control fertility. They also exhibit an unusual bipolar morphology comprised of a classical soma-proximal dendritic zone and an elongated secretory process ...
Li Wang, Wenya Guo, Xi Shen, Shel Yeo, Hui Long, Zhexuan Wang, Qifeng Lyu, Allan E Herbison, Yanping Kuang   +8 more
doaj   +1 more source

Relationship between Body Mass Index and Bone Turnover Markers in Girls with Idiopathic Central Precocious Puberty

International Journal of Clinical Practice, 2023
Background. This study aimed to determine the effect of body mass index (BMI) on bone turnover markers in girls with idiopathic central precocious puberty (ICPP) according to weight status at diagnosis. Methods.
Jing Zhang, Wen-jie Zhou, Yi-duo Zhang, Chuan-jiao Liu, Fan Yu, Yong-mei Jiang   +5 more
doaj   +1 more source