Genetic models for the study of luteinizing hormone receptor function [PDF]
Frontiers in Endocrinology, 2015 The luteinizing hormone/chorionic gonadotropin receptor, LHCGR, is essential for fertility in men and women. LHCGR binds luteinizing hormone (LH) as well as the highly homologous chorionic gonadotropin (CG).
Prema eNarayan
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Diseases, 2020 Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings.
Duaa Althumairy +6 more
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Characterization of luteinizing hormone and luteinizing hormone receptor and their indispensable role in the ovulatory process of the medaka. [PDF]
PLoS ONE, 2013 The molecular properties and roles of luteinizing hormone (Lh) and its receptor (Lhcgrbb) have not been studied for the medaka (Oryzias latipes), which is an excellent animal model for ovulation studies.
Katsueki Ogiwara +3 more
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Expression of the luteinizing hormone receptor (LHR) in ovarian cancer [PDF]
BMC Cancer, 2019 We investigated the association of LHR expression in epithelial ovarian cancer (OC) with clinical and pathologic characteristics of patients. LHR expression was examined immunohistochemically using tissue microarrays (TMAs) of specimens from 232 OC ...
Shigang Xiong +6 more
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Association of the genetic variants of luteinizing hormone, luteinizing hormone receptor and polycystic ovary syndrome [PDF]
Reproductive Biology and Endocrinology, 2012 Background High circulating luteinizing hormone (LH) level is a typical biochemical feature of polycystic ovary syndrome (PCOS) whose pathophysiology is still unclear.
Liu Nana +7 more
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Hormonal and Allosteric Regulation of the Luteinizing Hormone/Chorionic Gonadotropin Receptor
Frontiers in Bioscience-LandmarkLuteinizing hormone (LH) and human chorionic gonadotropin (CG), like follicle-stimulating hormone, are the most important regulators of the reproductive system.
Alexander O. Shpakov
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Plasticity of Anterior Pituitary Gonadotrope Cells Facilitates the Pre-Ovulatory LH Surge
Frontiers in Endocrinology, 2021 Gonadotropes cells located in the anterior pituitary gland are critical for reproductive fitness. A rapid surge in the serum concentration of luteinizing hormone (LH) secreted by anterior pituitary gonadotropes is essential for stimulating ovulation and ...
Colin M. Clay +2 more
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The hormone-binding unit of luteinizing hormone receptor [PDF]
Biochemical Journal, 1982 Rat ovarian luteinizing hormone/human choriogonadotropin binding sites were labelled with 125I-choriogonadotropin in vivo, and the resulting 125I-choriogonadotropin-receptor complexes were solubilized by Triton X-100 and purified by use of antibodies to choriogonadotropin immobilized to agarose. The purified 125I-choriogonadotropin-receptor complex was
M K, Metsikkö, H J, Rajaniemi
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Adrenal luteinizing hormone releasing hormone receptors. [PDF]
Journal of Histochemistry & Cytochemistry, 1978 Paraffin sections of mouse adrenals processed with antiserum to luteinizing hormone-releasing hormone (LHRH) in the unlabeled antibody enzyme method reveal moderate staining in the cytoplasm of cells of zona fasciculata and reticularis. The stain is intensified upon pretreatment of sections with LHRH.
L A, Bernardo +3 more
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Insulin receptor signaling in the GnRH neuron plays a role in the abnormal GnRH pulsatility of obese female mice. [PDF]
PLoS ONE, 2015 Infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. These tissues maintain insulin sensitivity upon peripheral insulin resistance.
Sara A DiVall +6 more
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