Results 41 to 50 of about 34,840 (229)

Intra‐Individual Variability of Blood and Urinary Steroid Markers and the Response to Codeine Intake in Healthy Men and Women

Drug Testing and Analysis, EarlyView.
Short‐term codeine administration (1–3 days) caused individual alterations in Athlete Biological Passport steroid markers, including elevated urinary T/E ratios and decreased serum testosterone concentrations below individual thresholds, despite no significant changes at the group level.
Alexander Andersson, Basam Yousif, Anton Pohanka, Annica Börjesson, Mikael Lehtihet, Lena Ekström   +5 more
wiley   +1 more source

A conformational contribution of the luteinizing hormone–receptor ectodomain to receptor activation [PDF]

Journal of Molecular Endocrinology, 2007
Abstract Glycoprotein hormone receptors such as the lutropin/chorionic gonadotropin receptor (LHR) are characterized by a large N-terminal ectodomain (ECD), which is responsible for hormone–receptor interactions. For the closely related TSH receptor (TSHR), it has been proposed that the ECD also serves as a tethered inverse agonist ...
Pascal, Nurwakagari, Andreas, Breit, Claudia, Hess, Hagar, Salman-Livny, David, Ben-Menahem, Thomas, Gudermann   +5 more
openaire   +2 more sources

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source

LHCGR (luteinizing hormone/choriogonadotropin receptor) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on LHCGR (luteinizing hormone/choriogonadotropin receptor), with data on DNA, on the protein encoded, and where the gene is implicated.
Tsai-Morris, CH, Dufau, ML
openaire   +3 more sources

The effect of ovarian stimulation protocol on follicular asynchrony during in vitro fertilization – A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to asynchrony. Methods A single‐center retrospective‐cohort study (January 2018–March 2024), including women undergoing IVF who had: (1) a ...
Alyssa Hochberg, Maria Hincapie, Uri Amikam, Nir Kugelman, William Buckett, Shauna Reinblatt   +5 more
wiley   +1 more source

Melatonin alleviates oxidative stress damage in mouse testes induced by bisphenol A

Frontiers in Cell and Developmental Biology
We investigated the effect of melatonin on bisphenol A (BPA)-induced oxidative stress damage in testicular tissue and Leydig cells. Mice were gavaged with 50 mg/kg BPA for 30 days, and concurrently, were injected with melatonin (10 mg/kg and 20 mg/kg ...
Qi Qi, Qi Qi, Jiaxin Yang, Shuang Li, Shuang Li, Jingjing Liu, Jingjing Liu, Da Xu, Guoqing Wang, Lei Feng, Xiaoyan Pan   +10 more
doaj   +1 more source

Expression of the gonadotropin receptors during follicular development

Reproductive Medicine and Biology, 2018
Background Gonadotropins induce follicular development that leads to ovulation and luteinization. In women, the level of gonadotropins, along with the expression of their receptors, changes dynamically throughout the menstrual cycle.
Hiroshi Kishi, Yoshikazu Kitahara, Fumiharu Imai, Kohshiro Nakao, Hiroto Suwa   +4 more
doaj   +1 more source

Association of a missense mutation in the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) with superovulation traits in Chinese Holstein heifers

Journal of Animal Science and Biotechnology, 2012
Background Upon binding luteinizing hormone in the ovary, the luteinizing hormone/choriogonadotropin receptor (LHCGR) is necessary for follicular maturation and ovulation, as well as luteal function.
Yu Yong, Pang Yunwei, Zhao Haichao, Xu Xiaoling, Wu Zhonghong, An Lei, Tian Jianhui   +6 more
doaj   +1 more source

Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells

Frontiers in Cell and Developmental Biology, 2021
Leydig cells (LC) are the main testicular androgen-producing cells. In eutherian mammals, two types of LCs emerge successively during testicular development, fetal Leydig cells (FLCs) and adult Leydig cells (ALCs). Both display significant differences in
Pauline Sararols, Isabelle Stévant, Yasmine Neirijnck, Diane Rebourcet, Annalucia Darbey, Michael K. Curley, Françoise Kühne, Emmanouil Dermitzakis, Emmanouil Dermitzakis, Lee B. Smith, Lee B. Smith, Serge Nef   +11 more
doaj   +1 more source

Pregnancy‐ and lactation‐associated osteoporosis: A position statement of the IAPM, IOF, ECTS, ESCEO, IMS, and EMAS

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a syndrome characterized by fragility fractures (most commonly vertebral, often multiple) occurring in late pregnancy or the early postpartum period. This position statement summarizes the current knowledge of PLO, and the recommended procedure for assessment, diagnosis and treatment ...
Peyman Hadji, Apostolos Athanasiadis, Maria‐Luisa Brandi, Marlene Chakhtoura, Manju Chandran, Frank Chervenak, Amos Grünebaum, Irene Lambrinoudaki, Willem F. Lems, Apostolos M. Mamopoulos, Eugene McCloskey, Rossella E. Nappi, Jessica Pepe, Jean‐Yves Reginster, René Rizzoli, Petra Stute, Şansın Tuzun, Amanda J. Vincent, Maria Belen Zanchetta, M. Carola Zillikens, Ioannis Kyvernitakis   +20 more
wiley   +1 more source