Results 21 to 30 of about 34,840 (229)
A Novel Human Luteinizing Hormone Receptor Gene [PDF]
The Journal of Clinical Endocrinology & Metabolism, 1998 A novel human luteinizing hormone receptor (LHR) gene was isolated from a human placental genomic library. This gene (Gene II) differs from that previously isolated from a lymphocyte library (Gene I) by several base changes in the 5' flanking region and the deletion of 6 nucleotides in the coding region (+55 to +60).
C H, Tsai-Morris +3 more
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Receptors for luteinizing hormone-releasing hormone. [PDF]
Journal of Histochemistry & Cytochemistry, 1978 Antisera to luteinizing hormone-releasing hormone (LH-RH) confer on Araldite sections of occasional rat pituitaries moderate immunocytochemical staining to the large secretory granules of gonadotrophs. Treatment of the sections with LH-RH before anti-LH-RH yields strong staining in all animals, irrespective of presence or absence of staining without ...
openaire +2 more sources
Regulation of human luteinizing hormone receptor in the ovary [PDF]
Reproductive Medicine and Biology, 2008 The luteinizing hormone receptor (LHR) is essential for elevated levels of progesterone to maintain pregnancy during the first trimester; the maintenance of the expression of LHR is a key factor controlling the duration of luteal function. Therefore, as the expression of LHR is most likely to be regulated by the stability of the receptor mRNA at the ...
Takashi, Minegishi +4 more
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BMC Cancer, 2011 Background Since a substantial percentage of ovarian cancers express gonadotropin receptors and are responsive to the relatively high concentrations of pituitary gonadotropins during the postmenopausal years, it has been suggested that receptor ...
Dam Phuongan +6 more
doaj +1 more source
A case of micropenis caused by compound heterozygote mutations in luteinizing hormone/choriogonadotropin receptor (LHCGR) [PDF]
Jichu yixue yu linchuang, 2022 Objective To investigate the pathogenic gene mutations and clinical characteristics in a patient with compound heterozygote gene mutations in luteinizing hormone/choriogonadotropin receptor (LHCGR) gene.
YANG Yu-fan, ZHAO Ya-ling, WANG Xi, NIE Min, WU Xue-yan, MAO Jiang-feng
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Hinge region mediates signal transmission of luteinizing hormone and chorionic gonadotropin receptor
Computational and Structural Biotechnology Journal, 2022 Luteinizing hormone-choriogonadotropin receptor (LHCGR), a class A G protein-coupled receptor (GPCR), plays a pivotal role in the maturation of reproductive organs and embryonic development.
Xinheng He +7 more
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Antisense mRNA for NPY-Y1 receptor in the medial preoptic area increases prolactin secretion
Brazilian Journal of Medical and Biological Research, 1999 We investigated the participation of neuropeptide Y-Y1 receptors within the medial preoptic area in luteinizing hormone, follicle-stimulating hormone and prolactin release.
N.A. Silveira, C.R. Franci
doaj +1 more source
Exploration of Targeted Anti-tumor Therapy, 2021 Adjuvant hormonal therapy is one of the most important treatments of hormone-receptor-positive breast cancer and includes selective estrogen receptor modulators, aromatase inhibitors, and luteinizing hormone-releasing hormone analogs.
Alfredo Rossi +4 more
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Molecular Mechanisms of Dysregulated LH and FSH Secretion in Human Reproductive Failure
BiomedicinesSeveral reproductive issues in both men and women are caused by changes in the pulsatile secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Athanasios Zikopoulos +9 more
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Frontiers in Oncology, 2021 Chemotherapy and endocrine therapies are mainstays of treatment for early and advanced hormone receptor-positive (HR+) breast cancer. In premenopausal women with HR+ tumors, the benefits of adding ovarian function suppression (OFS) to endocrine therapy ...
Yen-Shen Lu, Andrea Wong, Hee-Jeong Kim
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