Results 81 to 90 of about 447,250 (290)

Regulation of gene expression in ovarian cancer cells by luteinizing hormone receptor expression and activation

BMC Cancer, 2011
Background Since a substantial percentage of ovarian cancers express gonadotropin receptors and are responsive to the relatively high concentrations of pituitary gonadotropins during the postmenopausal years, it has been suggested that receptor ...
Dam Phuongan, Warrenfeltz Susanne W, Eldredge Joanna B, Miner Brooke M, Cui Juan, Xu Ying, Puett David   +6 more
doaj   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Effects of growth hormone administration on luteinizing hormone secretion in healthy older men and women

Physiological Reports, 2017
The known interactions between the somatotropic and hypothalamic‐pituitary‐gonadal (HPG) axes have not been well delineated in older individuals. Aging‐associated decline in insulin like growth factor‐1 (IGF‐1) levels has been proposed to play a role in ...
Ranganath Muniyappa, Shannon D. Sullivan, Sri Harsha Tella, Brent S. Abel, S. Mitchell Harman, Marc R. Blackman   +5 more
doaj   +1 more source

Elimination of luteinizing hormone cross-reactive epitopes from human chorionic gonadotropin

, 2002
The beta-chain of human chorionic gonadotropin (hCG) has been shown to have efficacy in clinical trials when used as a contraceptive vaccine. This hormone is a heterodimer, the alpha-chain being shared with the other members of the glycoprotein hormone ...
Lund, T., Roitt, I., Justesen, J., Roitt, I.M., Delves, P., Chiesa, M., Chikadze, N., Martensen, P., Delves, P.J., Porakishvili, N., Dalla Chiesa, M.   +10 more
core   +1 more source

Prevalence of HCMV, HHV‐6, and HSV‐1/2 in the semen of men attending infertility clinics and their association with semen parameters

UroPrecision, EarlyView.
Abstract Background Viral infections have been identified as potential disruptors of male reproductive health. This study aimed to investigate the prevalence of human cytomegalovirus (HCMV), human herpesvirus 6 (HHV‐6), and herpes simplex virus types 1 and 2 (HSV‐1/2) DNA in semen samples from fertile and infertile men within the potential impact of ...
Seyedeh Zahra Hashemi, Neda Pirbonyeh, Fahime Edalat, Narges Eslami, Saeed Tajik, Arash Letafati, Jamal Sarvari, Afagh Moattari   +7 more
wiley   +1 more source

Assessing physiological, behavioral and movement responses to Suprelorin implant delivery methods in free‐ranging eastern grey kangaroos Macropus giganteus

Wildlife Biology, EarlyView.
Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva, Sebastien Comte, Tamara Keeley, Maquel Brandimarti, Catherine A. Herbert   +4 more
wiley   +1 more source

Effect of Melatonin on the Luteinizing Hormone Release Induced by Clomiphene and Luteinizing Hormone-Releasing Hormone

Experimental Biology and Medicine, 1976
The effect of melatonin on the LH-release response after the administration of synthetic LH-RH and clomiphene citrate was investigated in adult male rats. The sc administration of melatonin (1 mg/day) for 6 days produced a significant decrease in serum LH levels and in seminal vesicles and ventral prostate weights.
J A, Moguilevsky, P, Scacchi, R, Deis, N O, Siseles   +3 more
openaire   +2 more sources

Reduction of testicular Luteinizing Hormone/Human Chorionic Gonadotropin receptors by [D-Trp 6]-Luteinizing Hormone Releasing Hormone in hypophysectomized rats

, 1979
Adult and immature male rats were hypophysectomized and injected daily with saline or 0.2 or 2 μg of superactive Luteinizing Hormone Releasing Hormone (LHRH) agonist, [D-Trp 6]-LHRH subcutaneously for seven days - with, or without, concomitant treatment ...
Arimura, A, Talbot, S, Schally, A.V, Serafini, P   +3 more
core   +1 more source