Results 101 to 110 of about 37,439 (280)

Luteolin for neurodegenerative diseases: a review

Pharmacological Reports
AbstractNeurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and multiple sclerosis affect millions of people around the world. In addition to age, which is a key factor contributing to the development of all neurodegenerative diseases, genetic and environmental components are also important risk factors ...
Dunuvilla Kavindi Jayawickreme, Cletus Ekwosi, Apurva Anand, Marta Andres-Mach, Piotr Wlaź, Katarzyna Socała   +5 more
openaire   +2 more sources

Anti‐Allergic Potential of Chamaecrista nomame and Its Compound Luteolin for Novel Asthma Therapy

Phytotherapy Research, EarlyView.
Chamaecrista nomame (CN) and its active compound luteolin attenuate allergic airway inflammation by inhibiting mast cell activation and suppressing NF‐κB/MAPK signaling, leading to reduced cytokine production and OVA‐specific IgE levels. ABSTRACT Asthma is a chronic inflammatory disease driven by dysregulated immune responses and mast cell activation ...
Tae Kyeom Kang, Myungsuk Kim, Tam Thi Le, Geon Park, Yuna Jung, Hyobin Jeong, Youngsang Yoo, Wook‐Bin Lee, Sang Hoon Jung   +8 more
wiley   +1 more source

Hydrogen peroxide-induced oxidative damage and apoptosis in endothelial cells: protection by luteolin

, 2011
[[abstract]]Oxidative stress has recently been implicated in the pathogenesis of atherosclerotic cardiovascular diseases. Dietary supplement of antioxidants has been reported to have beneficial effects on prevention of atherogenic diseases.
Pei-Tzu Hsu
core  

Induction of cell apoptosis by luteolin

, 2022
Uvod: Ulcerozni kolitis upalna je bolest koja zahvaća debelo crijevo te uzrokuje niz patoloških promjena na sluznici debelog crijeva. Promjene na sluznici jedan su od rizičnih čimbenika koji utiru put ka karcinomu debelog crijeva.
Repić, Ivana
core  

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Autophagy inhibitor chloroquine enhanced the cell death inducing effect of the flavonoid luteolin in metastatic squamous cell carcinoma cells.

PLoS ONE, 2012
BackgroundFlavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities.Methods & resultsIn this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell ...
Lien Verschooten, Kathleen Barrette, Sofie Van Kelst, Noemí Rubio Romero, Charlotte Proby, Rita De Vos, Patrizia Agostinis, Marjan Garmyn   +7 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Luteolin induced apoptosis in prostate cancer cells.

, 2013
(a) Cells were stained with Annexin V/PI, and apoptosis was determined using flow cytometry. PC-3 cells were treated with various concentrations of luteolin for 48 h, after which apoptosis was determined by annexin V/PI staining with flow cytometry.
Jia Luo (291145), Poyil Pratheeshkumar (291137), Donghern Kim (291143), Xin Wang (91924), Andrew Hitron (291141), Xianglin Shi (13689), Songze Ding (291140), Zhuo Zhang (72795), Sasidharan Padmaja Divya (291144), Jeong-Chae Lee (291142), Young-Ok Son (291138), Amit Budhraja (291139), Lei Wang (6656), Gang Chen (107840)   +13 more
core   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source