Results 101 to 110 of about 31,825 (224)

AI‐enabled engineering of hesperidin/ursodeoxycholic acid nanomedicine for synergistic treatment of drug‐induced liver injury

Smart Molecules, EarlyView.
An AI‐driven framework integrating disease‐network analysis, direction‐aware molecular screening, and carrier‐free co‐assembly engineering enables nanomedicine design. The dual‐constraint deep learning model predicts API–target affinity and regulatory direction to prioritize complementary APIs.
Kai Xiao, Meng Fan, Haoyu Zheng, Boyuan Gu, Shaowen Wang, Ziping Wu, Shiming Zhang, Xin Zhao, Wensheng Zhang, Quanxin Ning, Sigen A, Chao Yang, Huayi Sun, Ren Mo, Dan Shao   +14 more
wiley   +1 more source

Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds

The Chemical Record, EarlyView.
This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá, Patrick C. Nobre, Isabelly O. Ferreira, Juliano B. Azeredo, Vanessa Nascimento   +4 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Enhancing the fastness characteristics of weld‐dyed cotton and recycled nylon 6,6 fabrics via sodium alginate and titanium dioxide

Coloration Technology, EarlyView.
Abstract This study investigates a sustainable dyeing and finishing strategy for recycled nylon 6,6 and organic cotton fabrics dyed with weld. Following meta‐mordant dyeing using alum under Natural Organic Dye Standard (NODS)‐compliant conditions, the fabrics were subjected to functional finishing with titanium dioxide as a multifunctional ...
Recep Karadag, Fatma Zehra Engin Sagirli, Abdulkadir Pars   +2 more
wiley   +1 more source

An Overview of Pharmacology of Luteolin

Journal of Biomedical and Pharmaceutical Research
Luteolin is a Flavonoids recognized for its potent antioxidant, anti-inflammatory, and gastro protective properties, which collectively contribute to its relevance in promoting gastric health. Luteolin is widely found in various natural sources, particularly in fruits, vegetables, and herbs.
Nitesh Kumar, Divya Singh, Surbhi Jangir, Rakesh Sharma   +3 more
openaire   +1 more source

Evaluating Whole Fruit Feijoa Powder for Type 2 Diabetes Risk Prevention: A Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Low energy diets (LEDs) are effective for body weight (BW) loss and improvement of type 2 diabetes (T2D) risk biomarkers. Emerging evidence suggests that whole fruit feijoa powder, rich in polyphenols and abscisic acid, may further support T2D prevention.
I. A. Mohamed, I. R. Sequeira‐Bisson, J. J. Lim, L. D. Plank, R. Murphy, S. D. Poppitt, J. L. Miles‐Chan   +6 more
wiley   +1 more source

Clinical evaluation of a luteolin‐based dental gel on dental plaque accumulation and gingival inflammation in dogs

Journal of Small Animal Practice, EarlyView.
Objectives The objective of this study was to develop and evaluate the clinical effectiveness of a luteolin‐based dental gel in reducing microbial dental plaque accumulation and gingival bleeding in dogs, leveraging luteolin's known antimicrobial and anti‐inflammatory properties.
C. Papadaki, O. Lorida, G. Paschalidis, S. Papageorgiou, D. Christofilos, K. Theodoridis, A. Ν. Assimopoulou, C. Cholevas, L. Tsalikis, G. Koutouzidou, S. Papadimitriou   +10 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Integrated Metabolomics and Selection Signal Analysis Provide Insights Into the Selection for Flavonol Biosynthesis Associated With Lettuce Quality Improvement

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lettuce is a critical leafy vegetable consumed worldwide and is a substantial dietary source of health‐promoting compounds. Exploring changes in metabolism during lettuce domestication under artificial selection conditions is important to facilitate further breeding and cultivation for quality improvement.
Xiao Yang, Shiwei Wei, Ge Jin, Li Zhang, Ran Du, Yajun Wang, Chengcheng Shen, Tao Huang, Guotao Huo, Jie Peng, Bo Song, Fangyuan Zhang, Victor Hugo Escalona Contreras, Lijun Luo, Yuejian Li, Francisco A. Tomas‐Barberan, Bin Liu, Qichang Yang   +17 more
wiley   +1 more source

Study on The Effect and Mechanism of Luteolin Against Mycoplasma pneumoniae

Shengwu huaxue yu shengwu wuli jinzhan
ObjectiveThis study aimed to investigate the anti-Mycoplasma pneumoniae (MP) activity of luteolin and elucidate its underlying mechanisms.MethodsLuteolin was identified as the primary active compound from the polyphenol extract of F.
OU Xia, LIU Zhao-Hong, TANG Lei, XIA Jian-Ming, YANG Kai, DING Kai-Yi, LIAO Guo-Yang, LIU Ze, ZHANG Ji-Hong   +8 more
doaj   +1 more source