Results 21 to 30 of about 31,825 (224)

Investigation on the Anticonvulsant Potential of Luteolin and Micronized Luteolin in Adult Zebrafish (Danio rerio)

Neurochemical Research, 2021
Epilepsy affects around 50 million people worldwide, and an important number of patients (30%) fail to respond to any available antiepileptic drug. Previous studies have shown that luteolin presents a promising potential as an anticonvulsant. On the other hand, different studies showed that luteolin does not promote anticonvulsant effects.
Cristiane Garbinato, Cássia Alves Lima-Rezende, Sabrina Ester Schneider, Jefferson Pedroso, Aline E. dos Santos, Fernanda Petry, Gean Pablo S. Aguiar, Liz Girardi Müller, Marcelo Lanza, Angelo Piato, J. Vladimir Oliveira, Anna Maria Siebel   +11 more
openaire   +3 more sources

Luteolin alleviated neutrophilic asthma by inhibiting IL-36γ secretion-mediated MAPK pathways

Pharmaceutical Biology, 2023
Context Luteolin can affect multiple biological functions, such as anti-inflammatory, antioxidant and immune enhancement processes. Luteolin can inhibit inflammation of T2-high asthma, but its role in neutrophilic asthma has been insufficently studied ...
Xin-rui Qiao, Tao Feng, Dong Zhang, Li-li Zhi, Jin-tao Zhang, Xiao-fei Liu, Yun Pan, Jia-wei Xu, Wen-Jing Cui, Liang Dong   +9 more
doaj   +1 more source

Characterization and Quantification of Luteolin-Metal Complexes in Aqueous Extract of Lonicerae Japonicae Flos and Huangshan Wild Chrysanthemum

International Journal of Analytical Chemistry, 2021
Luteolin is a flavonoid compound widely found in vegetables, fruits, and medicinal plants. In this study, the reaction conditions for luteolin and five metal ions (Ca2+, Mg2+, Zn2+, Fe3+, and Cu2+) to form complexes in hot water were optimized, which was
Weilan Cai, Yunhao Xiong, Manman Han, Zhimin Li, Liang Peng, Hongyi Zhang, Qin Zou, Lin Wu, Qingling Ye, Linfeng Liao   +9 more
doaj   +1 more source

CXXVI.—Luteolin. Part III [PDF]

J. Chem. Soc., Trans., 1900
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Perkin, Arthur George, Horsfall, Louis Hubert   +1 more
openaire   +1 more source

The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation

Frontiers in Molecular Neuroscience, 2019
Luteolin, a polyphenolic plant flavonoid, has been attributed with numerous beneficial properties like anti-cancer, antioxidant, and anti-inflammatory action.
Amrutha Swaminathan, Amrutha Swaminathan, Moumita Basu, Abdelhamid Bekri, Abdelhamid Bekri, Pierre Drapeau, Pierre Drapeau, Tapas K. Kundu   +7 more
doaj   +1 more source

Polysaccharides from Citrus grandis associate with luteolin relieves chronic pharyngitis by anti-inflammatory via suppressing NF-κB pathway and the polarization of M1 macrophages

International Journal of Immunopathology and Pharmacology, 2018
Chronic pharyngitis is characterized as a common inflammation of the pharyngeal mucosa, and anti-inflammatory medications are the common treatment to relieve it. Polysacharides of Citrus grandis L.
Xiumei Chen, Yongfeng Lai, Xicheng Song, Jinying Wu, Li Wang, Hua Zhang, Zhonglu Liu, Yan Wang   +7 more
doaj   +1 more source

Luteolin and micronized luteolin show antiseizure effects in developing zebrafish

, 2022
Abstract Seizure is one of the most frequent neurological emergencies among neonates. Seizures during neurodevelopment could promote epileptogenesis by triggering inflammatory cascades and potentiating mTOR signaling. Epileptogenesis contemplates disrupted neurogenesis and neurodegeneration; and culminates in epilepsy. Epileptic patients suffer
Sabrina Ester Schneider, Jefferson Pedroso, Cássia Alves Lima-Rezende, Aline E. dos Santos, Gean Pablo S. Aguiar, Marcelo Lanza, Liz Girardi Müller, J. Vladimir Oliveira, Angelo Piato, Anna Siebel   +9 more
openaire   +1 more source

Application of Luteolin in Neoplasms and Nonneoplastic Diseases

International Journal of Molecular Sciences, 2023
Researchers are amazed at the multitude of biological effects of 3′,4′,5,7-tetrahydroxyflavone, more commonly known as luteolin, as it simultaneously has antioxidant and pro-oxidant, as well as antimicrobial, anti-inflammatory, and cancer-preventive, properties.
Katarzyna Rakoczy, Justyna Kaczor, Adam Sołtyk, Natalia Szymańska, Jakub Stecko, Jakub Sleziak, Julita Kulbacka, Dagmara Baczyńska   +7 more
openaire   +2 more sources

Intestinal absorption of luteolin and luteolin 7‐O‐β‐glucoside in rats and humans [PDF]

FEBS Letters, 1998
In this study, we investigated the intestinal absorption of luteolin and luteolin 7‐O‐β‐glucoside in rats by HPLC. The absorption analysis using rat everted small intestine demonstrated that luteolin was converted to glucuronides during passing through the intestinal mucosa and that luteolin 7‐O‐β‐glucoside was absorbed after hydrolysis to luteolin ...
Shimoi, Kayoko, Okada, Hisae, Furugori, Michiyo, Goda, Toshinao, Takase, Sachiko, Suzuki, Masayuki, Hara, Yukihiko, Yamamoto, Hiroyo, Kinae, Naohide   +8 more
openaire   +2 more sources

Structure modification of luteolin and the influence of its derivatives on biological activities

Frontiers in Nutrition
IntroductionThis research aims to synthesize luteolin derivatives from hemp seeds by means of chemical synthesis, improve the synthesis process, simplify the procedure, and increase the yield to obtain new luteolin derivatives.
Lingyang Kong, Wei Wu, Chenliang Li, Lengleng Ma, Junbai Ma, Meitong Pan, Shan Jiang, Weili Liu, Jiao Xu, Jiao Xu, Wei Ma   +10 more
doaj   +1 more source