Results 21 to 30 of about 37,439 (280)

Luteolin-mediated TB immunity prevents disease relapses.

, 2021
M.tb infected mice were treated with Isoniazid or Isoniazid+Luteolin for 120 days and then rested for another 30 days. Then, one group was reinfected with M.tb and a second group was treated with dexamethasone for 30 days.
Annu Devi (11307913), Sultan Tousif (351873), Barnani Moitra (11307919), Dhiraj Kumar Singh (9402208), Anand Ranganathan (197875), Kriti Negi (11307916), Gobardhan Das (186981), Ashima Bhaskar (353235), Ved Prakash Dwivedi (9402211)   +8 more
core   +1 more source

The antitumour effect of galangin and luteolin with doxorubicin on chemically induced hepatocellular carcinoma in rats

, 2021
Egypt Hepatocellular carcinoma (HCC), a highly malignant tumour with very high morbidity and mortality, remains the second cause of cancer-related deaths worldwide.
Gamal Omran, Atef Abd Elbaky, Gamal Atwa, Tarek Okda   +3 more
core   +1 more source

Protective effects of luteolin on injury induced inflammation through reduction of tissue uric acid and pro-inflammatory cytokines in rats

Journal of Traditional and Complementary Medicine, 2020
Background and aim: Luteolin belongs to flavone group of flavonoids, present in many plants with potent antioxidant, anti-inflammatory and anti-proliferative effects.
Santram Lodhi, Gautam P. Vadnere, Kiran D. Patil, Tushar P. Patil   +3 more
doaj   +1 more source

Influence of luteolin on the apoptosis of esophageal cancer Eca109 cells and its mechanism of action

Food Science and Human Wellness, 2019
The present study was conducted to verify the influence of luteolin on apoptosis of Eca109 cells and to further investigate the possible mechanisms underlying its effect on apoptosis. The cells were exposed to different concentrations of luteolin (0, 40,
Shaokang Wang, Lingmeng Fu, Yi Wu, Hongmei Xiao, Jing Wang, Guiju Sun   +5 more
doaj   +1 more source

Luteolin Ameliorates Experimental Pulmonary Arterial Hypertension via Suppressing Hippo-YAP/PI3K/AKT Signaling Pathway

Frontiers in Pharmacology, 2021
Luteolin is a flavonoid compound with a variety of pharmacological effects. In this study, we explored the effects of luteolin on monocrotaline (MCT) induced rat pulmonary arterial hypertension (PAH) and underlying mechanisms.
Wanyun Zuo, Na Liu, Yunhong Zeng, Zhenghui Xiao, Keke Wu, Fan Yang, Biao Li, Qingqing Song, Yunbin Xiao, Qiming Liu   +9 more
doaj   +1 more source

Luteolin Attenuates Allergic Nasal Inflammation via Inhibition of Interleukin-4 in an Allergic Rhinitis Mouse Model and Peripheral Blood From Human Subjects With Allergic Rhinitis

Frontiers in Pharmacology, 2020
Objectives: Luteolin is the active component of Perilla frutescens, an herb for the treatment of allergy in Asia. In this study, we aimed to investigate the effects and mechanisms of luteolin treatment.Methods: BALB/c mice sensitized with house dust mite
Kai-Li Liang, Kai-Li Liang, Kai-Li Liang, Sheng-Jie Yu, Wan-Chun Huang, Hung-Rong Yen, Hung-Rong Yen, Hung-Rong Yen, Hung-Rong Yen, Hung-Rong Yen   +9 more
doaj   +1 more source

Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats

Frontiers in Pharmacology, 2021
Misuse of the psychostimulant methamphetamine (METH) could induce serious hepatotoxicity. Our previous study revealed the effects of luteolin on alleviating METH-induced hepatotoxicity, however, the detailed mechanisms have not been elucidated.
Kai-Kai Zhang, Hui Wang, Dong Qu, Li-Jian Chen, Li-Bin Wang, Jia-Hao Li, Jia-Li Liu, Ling-Ling Xu, Jamie Still Yoshida, Jing-Tao Xu, Jing-Tao Xu, Xiao-Li Xie, Dong-Ri Li   +12 more
doaj   +1 more source

Glycosylation of luteolin in hydrophilic organic solvents and structure–antioxidant relationships of luteolin glycosides

RSC Advances, 2022
Efficient glycosylation of luteolin in organic solvents and the structure–antioxidant relationships of luteolin glycosides were reported for the first time.
Tingting Xu, Chen Wang, Sijie Jiang, Tingting Yang, Xueming Wu   +4 more
openaire   +2 more sources

Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion

Journal of Ovarian Research, 2018
Luteolin, a polyphenolic flavone, has been demonstrated to exert anti-tumor activity in various cancer types. Cisplatin drug resistance is a major obstacle in the management of ovarian cancer.
Haixia Wang, Youjun Luo, Tiankui Qiao, Zhaoxia Wu, Zhonghua Huang   +4 more
doaj   +1 more source

Luteolin increases susceptibility to macrolides by inhibiting MsrA efflux pump in Trueperella pyogenes

Veterinary Research, 2022
Trueperella pyogenes (T. pyogenes) is an opportunistic pathogen associated with a variety of diseases in many domestic animals. Therapeutic treatment options for T. pyogenes infections are becoming limited due to antimicrobial resistance, in which efflux
Yuru Guo, Chengcheng Huang, Hongyu Su, Zehui Zhang, Menghan Chen, Ruxia Wang, Dexian Zhang, Luyao Zhang, Mingchun Liu   +8 more
doaj   +1 more source