Results 141 to 150 of about 197,995 (383)

Intricate Regulation of Sphingolipid Biosynthesis: An In‐Depth Look Into ORMDL‐Mediated Regulation of Serine Palmitoyltransferase

BioEssays, EarlyView.
Multiple enzymes play a crucial role in regulating the biosynthesis of de novo sphingolipids. This regulation starts with the rate‐limiting enzyme, serine palmitoyltransferase (SPT), which catalyzes the first step of the pathway. Disruptions in this regulatory process can lead to serious diseases.
Usha Mahawar, Binks Wattenberg
wiley   +1 more source

Characterization of a New Cold-Adapted and Salt-Activated Polysaccharide Lyase Family 7 Alginate Lyase from Pseudoalteromonas sp. SM0524

Frontiers in Microbiology, 2016
Marine bacterial alginate lyases play a role in marine alginate degradation and carbon cycling. Although a large number of alginate lyases have been characterized, reports on alginate lyases with special characteristics are still rather less.
Xiulan Chen, Sheng Dong, Fei Xu, F. Dong, Ping-Yi Li, Xi-Ying Zhang, Bai-cheng Zhou, Yu-Zhong Zhang, B. Xie   +8 more
semanticscholar   +1 more source

Use of LC‐MS to characterize host cell protein removal during depth filtration

Biotechnology Progress, EarlyView.
Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu, Ehsan Espah Borujeni, Xuankuo Xu, Andrew L. Zydney   +3 more
wiley   +1 more source

Discovery of a Novel Alginate Lyase from Nitratiruptor sp. SB155-2 Thriving at Deep-sea Hydrothermal Vents and Identification of the Residues Responsible for Its Heat Stability*

Journal of Biological Chemistry, 2016
Extremophiles are expected to represent a source of enzymes having unique functional properties. The hypothetical protein NIS_0185, termed NitAly in this study, was identified as an alginate lyase-homolog protein in the genomic database of ϵ ...
A. Inoue, M. Anraku, S. Nakagawa, T. Ojima   +3 more
semanticscholar   +1 more source

UPLC‐ESI‐QTOF‐MS/MS Profiling, Antioxidant, and Cytotoxicity Potentials of Marrubium vulgare L. Extracts: Experimental Analysis and Computational Validation

Chemistry &Biodiversity, EarlyView.
ABSTRACT Plant extracts are emerging as valuable options for food additives and therapeutic treatments. This study evaluated the phytochemical profile, antioxidant activity, and cytotoxicity of aerial parts of Marrubium vulgare L. crude extract (MVCE) and its subfractions.
Ines El Mannoubi, Nuha M. Alghamdi, Seham H. Bashir, Suada Alsaied Mohamed, Hedia Chaabane, Ashraf N. Abdalla, Majdi Abid, Adel Kadri, Mozaniel Santana de Oliveira   +8 more
wiley   +1 more source

5-Aminolaevulinate hydro-lyase from yeast isolation and purification [PDF]

, 1967
Ofelia L. Clara de Barreiro
openalex   +1 more source

Structure of the prosthetic groups of citrate lyase and citramalate lyase [PDF]

FEBS Letters, 1977
Rosemarie Loyal, Peter Dimroth
openaire   +3 more sources

5‐thiohistidine N‐acetyltransferase from Proteiniphilum saccharofermentans

ChemBioChem, Accepted Article.
Ovothiol A is a 5‐thiohistidine derivative biosynthesized by a broad range of prokaryotic and eukaryotic organisms. Its redox‐active mercaptoimidazole side chain is believed to protect cells from oxidative stress. The three enzymes that produce ovothiol A from histidine, cysteine, and S‐adenosyl methionine have been identified and characterized.
Cangsong Liao, David Lim, Gladwin Suryatin Alim, Florian P. Seebeck   +3 more
wiley   +1 more source

Overexpression of Phenylalanine Ammonia-Lyase in Transgenic Roots of Coleus blumei Alters Growth and Rosmarinic Acid Synthesis

Food Technology and Biotechnology, 2011
Most natural phenolic compounds in plants are derived from trans-cinnamic acid, formed by the nonoxidative deamination of L-phenylalanine by phenylalanine ammonia-lyase (EC 4.3.1.24). Although a strict line between primary and secondary metabolism cannot
Hrvoje Fulgosi, Sibila Jelaska, Nataša Bauer   +2 more
doaj  

CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs

Frontiers in Cellular and Infection Microbiology, 2018
Bacterial citrate lyase activity has been demonstrated in various eukaryotes, bacteria and archaea, underscoring their importance in energy metabolism of the cell. While the bacterial citrate lyase comprises of three different subunits, M.
Garima Arora, Garima Arora, Deepika Chaudhary, Deepika Chaudhary, Saqib Kidwai, Deepak Sharma, Ramandeep Singh   +6 more
doaj   +1 more source