Results 161 to 170 of about 206,376 (396)

Accelerating Enzyme Engineering With Artificial Intelligence in Biocatalysis: Challenges and Opportunities

Food Bioengineering, EarlyView.
ABSTRACT Artificial intelligence (AI) has emerged as a paradigm‐shifting force in enzyme engineering, enabling data‐driven prediction of catalytic activity, stability, and substrate specificity. By integrating large‐scale datasets from structured databases (e.g., PDB, BRENDA) and high‐throughput experimentation (e.g., deep mutational scanning ...
Xiafeng Lu, Min Cao, Muqing Ma, Yan Wu, Maohua Qu, Feng Du, Rongtao Ji, Mimi Duan, Leichi Dong, Kai Liu, Xueqi Zhang, Zhibo Luo   +11 more
wiley   +1 more source

Effects of virus infection on release of volatile organic compounds from insect-damaged bean, Phaseolus vulgaris [PDF]

, 2003
Insects can serve as important vectors of plant pathogens, especially viruses. Insect feeding on plants causes the systemic release of a wide range of plant volatile compounds that can serve as an indirect plant defense by attracting natural enemies of ...
Drumwright, B. Alison, Erf, Gisela F., Jackson, Britney K., Korth, Kenneth L., Sossamon, Sarah E.   +4 more
core   +2 more sources

Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation

, 2020
Piming Zhao, Isaac D Liu, Jeffrey B. Hodgin, Peter I. Benke, Jeremy Selva, Federico Torta, Markus R. Wenk, James A. Endrizzi, O.R. West, Weixing Ou, Emily Tang, Denise Li‐Meng Goh, S K Tay, Hui‐Kim Yap, Alwin Hwai Liang Loh, Nicole Davis Weaver, Bonnie Sullivan, Austin Larson, Megan A. Cooper, Khalid Alhasan, Abdullah Alangari, Suha Salim, Evren Gümüş, Karin Chen, Martin Zenker, Friedhelm Hildebrandt, Julie D. Saba   +26 more
openalex   +2 more sources

Influence of Bacillus amyloliquefaciens subsp. plantarum IMV B-7404 strain exometabolites on phenylalanine ammonia-lyase activity in winter wheat seedlings [PDF]

, 2015
I.V. Dragovoz
openalex   +1 more source

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, EarlyView.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

SiO2–alginate–melittin nano-conjugates suppress the proliferation of ovarian cancer cells: a controlled release approach leveraging alginate lyase

Cancer Nanotechnology
Background Ovarian cancer treatment is challenged by resistance and off-target effects. Melittin shows promise against cancer but is limited by its instability and harmful cellular interactions. Our study introduces SiO2–alginate–melittin nano-conjugates
Lihui Si, Shuli Yang, Ruixin Lin, Shiyu Gu, Chuhan Yan, Jia Yan   +5 more
doaj   +1 more source

Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase [PDF]

, 2012
Jeffrey G. Dickhout, Rachel E. Carlisle, Danielle E. Jerome, Zahraa Mohammed‐Ali, Hua Jiang, Guangdong Yang, G. Balasubramanian, Sanjay K. Garg, Ruma Banerjee, Randal J. Kaufman, Kenneth N. Maclean, Rui Wang, Richard C. Austin   +12 more
openalex   +1 more source

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

Science, 2009
K. Wellen, G. Hatzivassiliou, Uma M. Sachdeva, Thi V Bui, J. Cross, C. Thompson   +5 more
semanticscholar   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]

, 2004
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
core