Results 211 to 220 of about 206,376 (396)

Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin

, 2021
Haoran Xu, Kang Wei, Jingyao Tu, Yangmengfan Chen, Ying He, Yifan Ding, Huanhuan Xu, Xinyu Bao, Hui Xie, Huang Fang, Huan Wang   +10 more
openalex   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Sphingosine 1-phosphate lyase (S1P lyase) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Taxonomic and functional shifts in the microbiome of severely obese, prediabetic patients: Ketogenic diet versus energy‐matched standard diet

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity and type 2 diabetes mellitus (T2DM) are among the leading global health challenges of the 21st century. While caloric restriction remains the cornerstone of weight loss interventions, ketogenic diets (KD), characterised by low carbohydrate and high fat intake, have been shown to improve metabolic health partly by modulating the ...
June Stone, Afroditi Tripyla, Melanie C. Scalise, Maria L. Balmer, Lia Bally, Dominik M. Meinel   +5 more
wiley   +1 more source

A Horizontally Transferred Alginate Metabolism Gene Cluster in the Human Gut Genus <i>Bacteroides</i>. [PDF]

J Appl Glycosci (1999)
Miyamoto Y, Katsuhiro N, Okumura K, Takase R, Watanabe D, Ogura K, Hashimoto W.   +6 more
europepmc   +1 more source

The specific molecular architecture of plant 3-hydroxy-3-methylglutaryl-CoA lyase

, 2019
Andréa Hemmerlin, Alexandre Huchelmann, Denis Tritsch, Hubert Schaller, Thomas J. Bach   +4 more
openalex   +1 more source

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt, Marcel Benkhoff, Nathalie H. Schröder, Hao Hu, Lisa Dannenberg, Petra Keul, Theresia Sarabhai, Kálmán Benedikt Bódis, Tobias Zeus, Philipp Wollnitzke, Malte Kelm, Amin Polzin, Bodo Levkau   +12 more
wiley   +1 more source

Timely intervention in HMG-CoA Lyase deficiency: The role of newborn screening, metabolic management, and genomic sequencing. [PDF]

Mol Genet Metab Rep
Menkovic I, Makhijani N, Francescatto L, Pendyal S, Stanley C, Young SP, Koeberl DD, Niyazov D, Stiles AR.   +8 more
europepmc   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Genome Analysis of Alginate-Degrading Bacterium <i>Vibrio</i> sp. 32415 and Optimization of Alginate Lyase Production. [PDF]

Microorganisms
Zeng Y, Xu J, Li Z, Wei R, Zhao H, Sun L, Lu C.   +6 more
europepmc   +1 more source