Results 261 to 270 of about 197,995 (383)

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Mode of Action of AlgE1: A Modular Mannuronate C-5 Epimerase. [PDF]

Biochemistry
Petersen AB, Solem A, Sætrom GI, Sletta H, Czjzek M, Aachmann FL, Tøndervik A.   +6 more
europepmc   +1 more source

Phenylalanine ammonia-lyase. Induction and purification from yeast and clearance in mammals.

, 1976
Richard R. Fritz, Daniel S. Hodgins, Creed W. Abell   +2 more
openalex   +1 more source

Regulation of L-phenylalanine ammonia-lyase from Rhizoctonia solani [PDF]

, 1976
Krishna Kalghatgi, P. Sriramarao
openalex   +1 more source

The disease‐linked R336C mutation in cystathionine β‐synthase disrupts communication with the PLP cofactor, yet maintains the enzyme's overall structural integrity

The FEBS Journal, EarlyView.
Cystathionine β‐synthase (CBS) is an essential enzyme involved in cysteine metabolism. The mutation R336C, associated with severe homocystinuria and of high incidence in Qatar, reduces its activity. Our research shows that this mutation does not destabilize the enzyme fold but subtly alters the tautomeric equilibrium of the PLP cofactor within the ...
Carolina Conter, Reyes Núñez‐Franco, Duaa Walid Al‐Sadeq, Carmen Fernández‐Rodríguez, Naroa Goikoetxea‐Usandizaga, Gheyath K. Nasrallah, Michail Nomikos, Maria Luz Martinez‐Chantar, Alessandra Astegno, Gonzalo Jiménez‐Osés, Luis Alfonso Martínez‐Cruz   +10 more
wiley   +1 more source

Exploring the Influence of Different <i>Saccharomyces cerevisiae</i> Strains and Hop Varieties on Beer Composition and Sensory Profiles. [PDF]

Foods
Costantini A, Petrozziello M, Tsolakis C, Asproudi A, Vaudano E, Pulcini L, Bonello F, Carbone K, Cravero MC.   +8 more
europepmc   +1 more source

Specificity of adenylosuccinate synthetase and adenylosuccinate lyase from Leishmania donovani. Selective amination of an antiprotozoal agent.

, 1979
T Spector, Thomas Jones, Gertrude B. Elion   +2 more
openalex   +1 more source

Genomic context analysis enables the discovery of an unusual NAD‐dependent racemase in phosphonate catabolism

The FEBS Journal, EarlyView.
The authors identify PbfF (previously annotated as a NAD‐dependent dehydrogenase) as a hitherto unknown enzyme in phosphonate catabolism. Guided by genome context analysis, they show that PbfF is actually a racemase, serving to degrade the natural compound (S)‐2‐amino‐1‐hydroxyethylphosphonate (S‐HAEP).
Francesca Ruffolo, Silvia Conciatori, Giovanni Merici, Tamara Dinhof, Jason P. Chin, Claudio Rivetti, Andrea Secchi, Katharina Pallitsch, Alessio Peracchi   +8 more
wiley   +1 more source

Garlic allergy in an infant: Identification of alliin lyase 1 and 2 as causative allergens. [PDF]

Asia Pac Allergy
Morita Y, Tsuchiya K, Sogawa K, Shimojo N.   +3 more
europepmc   +1 more source

Fat cell protein phosphorylation. Identification of phosphoprotein-2 as ATP-citrate lyase.

, 1979
S. Anantha Ramakrishna, Benjamin Wagner
openalex   +1 more source