Results 61 to 70 of about 197,995 (383)

Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models. [PDF]

, 2018
An excessive requirement for methionine (MET) for growth, termed MET dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by MET restriction such as with recombinant ...
Chemielwski, Bartosz, Dry, Sarah M, Eckardt, Mark A, Eilber, Fritz C, Han, Qinghong, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Shukuan, Li, Yunfeng, Miyake, Kentaro, Miyake, Masuyo, Nelson, Scott D, Russell, Tara A, Singh, Arun S, Tan, Yuying, Unno, Michiaki   +17 more
core   +1 more source

Characterization of an Alkaline Alginate Lyase with pH-Stable and Thermo-Tolerance Property

Marine Drugs, 2019
Alginate oligosaccharides (AOS) show versatile bioactivities. Although various alginate lyases have been characterized, enzymes with special characteristics are still rare. In this study, a polysaccharide lyase family 7 (PL7) alginate lyase-encoding gene,
Yanan Wang, Xue-hong Chen, Xiaolin Bi, Yining Ren, Qi Han, Yu Zhou, Yan-tao Han, Ruyong Yao, Shangyong Li   +8 more
semanticscholar   +1 more source

Functional identification of alginate lyase from the brown alga Saccharina japonica

Scientific Reports, 2019
Despite the progress in massive gene analysis of brown algal species, no alginate-degrading enzyme from brown alga has been identified, impeding the understanding of alginate metabolism in brown alga. In the current study, we identified and characterized
A. Inoue, T. Ojima
semanticscholar   +1 more source

Estradiol of various saturation and its influence on hydrogen sulfide formation in the myocardium of female rats. [PDF]

Medičnì Perspektivi, 2015
Hydrogen sulfide is signalling molecule that regulates vascular tone and myocardial contractility. Role of estradiol in hydrogen sulfide production in cardiovascular system of rats remains unclear and this becames research objective.
A. V. Melnik
doaj   +2 more sources

Characterization of degradation patterns and enzymatic properties of a novel alkali-resistant alginate lyase AlyRm1 from Rubrivirga marina

Current Research in Food Science, 2023
Alginate lyase is essential for the production of alginate oligosaccharides (AOSs), which exhibit diverse bioactivities and have numerous applications in the food and pharmaceutical industries.
Yuting Zheng, Yujie Wang, Meiling Dan, Yanping Li, Guohua Zhao, Damao Wang   +5 more
doaj  

Functional Characterization of a Novel Oligoalginate Lyase of Stenotrophomonas maltophilia KJ-2 Using Site-Specific Mutation Reveals Bifunctional Mode of Action, Possessing Both Endolytic and Exolytic Degradation Activity Toward Alginate in Seaweed Biomass

Frontiers in Marine Science, 2020
A novel oligoalginate lyase from the marine bacterium, Stenotrophomonas maltophilia KJ-2, completely depolymerizes alginate to monomers with generation of oligomer intermediates.
Yoo Jung Chu, Hae Sol Kim, Myung Sun Kim, Eun Yeol Lee, Hee Sook Kim   +4 more
doaj   +1 more source

Crystal structure and DNA cleavage mechanism of the restriction DNA glycosylase R.CcoLI from Campylobacter coli

Scientific Reports, 2021
While most restriction enzymes catalyze the hydrolysis of phosphodiester bonds at specific nucleotide sequences in DNA, restriction enzymes of the HALFPIPE superfamily cleave N-glycosidic bonds, similar to DNA glycosylases.
Ken-ichi Miyazono, Delong Wang, Tomoko Ito, Masaru Tanokura   +3 more
doaj   +1 more source

Alginate Lyase of a Novel Algae Fermentation Strain [PDF]

Chemical and Biochemical Engineering Quarterly, 2019
A novel algae fermentation strain was obtained in our previous work. This strain can produce alginate lyase and alcohol dehydrogenase used for the ethanol fermentation from algae.
W. Zhang, X. Xia, Z. Zhang
doaj   +1 more source

Genetic and biochemical analyses of chromosome and plasmid gene homologues encoding ICL and ArCP domains in Vibrioanguillarum strain 775 [PDF]

, 2011
Anguibactin, the siderophore produced by Vibrio anguillarum 775 is synthesized from 2,3-dihydroxybenzoic acid (DHBA), cysteine and hydroxyhistamine via a nonribosomal peptide synthetase (NRPS) mechanism.
AF Alice, AM Gehring, B Schwyn, C Notredame, CG Marshall, DH Figurski, EJ Drake, EL Arnow, F Bolivar, F Rusnak, H Naka, HW Boyer, J Frey, J Sambrook, JF Parsons, JF Staab, JH Crosa, JH Crosa, Jorge H. Crosa, JR Lai, JR Pollack, KA Datsenko, LA Actis, LA Actis, LE Quadri, M Balado, M Di Lorenzo, M Di Lorenzo, M Di Lorenzo, M Hahn, M Jalal, M Stork, MA Walter, Manuela Di Lorenzo, ME Tolmasky, ME Tolmasky, Michiel Stork, MK Wolf, PA Bates, Q Chen, RF Conchas, SF Altschul, TA Keating, TJ Welch   +43 more
core   +2 more sources

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

Advanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source