Results 61 to 70 of about 214,299 (407)
Estradiol of various saturation and its influence on hydrogen sulfide formation in the myocardium of female rats. [PDF]
Medičnì Perspektivi, 2015 Hydrogen sulfide is signalling molecule that regulates vascular tone and myocardial contractility. Role of estradiol in hydrogen sulfide production in cardiovascular system of rats remains unclear and this becames research objective.
A. V. Melnik
doaj +2 more sources
Scientific Reports, 2021 While most restriction enzymes catalyze the hydrolysis of phosphodiester bonds at specific nucleotide sequences in DNA, restriction enzymes of the HALFPIPE superfamily cleave N-glycosidic bonds, similar to DNA glycosylases.
Ken-ichi Miyazono +3 more
doaj +1 more source
Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]
, 2016 The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R. +2 more
core +4 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
Alginate Lyase of a Novel Algae Fermentation Strain [PDF]
Chemical and Biochemical Engineering Quarterly, 2019 A novel algae fermentation strain was obtained in our previous work. This strain can produce alginate lyase and alcohol dehydrogenase used for the ethanol fermentation from algae.
W. Zhang, X. Xia, Z. Zhang
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Biogenesis of cytochrome c1 [PDF]
, 1989 The biogenesis of cytochrome c1 involves a number of steps including: synthesis as a precursor with a bipartite signal sequence, transfer across the outer and inner mitochondrial membranes, removal of the first part of the presequence in the matrix ...
Neupert, Walter +2 more
core
Rational Design of Alginate Lyase from Microbulbifer sp. Q7 to Improve Thermal Stability
Marine Drugs, 2019 Alginate lyase degrades alginate by the β-elimination mechanism to produce oligosaccharides with special bioactivities. The low thermal stability of alginate lyase limits its industrial application.
Min Yang +5 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2020 目的探讨S1P lyase在肝癌中的表达情况,及其对肝癌预后的影响。方法选取桂林医学院附属医院54例肝细胞癌患者,real-time PCR分析S1P lyase在54对肝细胞癌癌组织及癌旁组织中的表达,运用统计学方法探讨S1P lyase表达与肝癌临床病理特征的关系;利用Kaplan-Meier分析S1P lyase对肝癌预后的影响;应用STRING数据库初步探讨神经鞘脂信号通路中可能与S1P lyase相互作用的信号分子。结果 S1P lyase在肝癌组织中的表达明显低于癌旁组织 ...
邱志东 +3 more
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