Results 61 to 70 of about 101,870 (311)

ATP Citrate Lyase is a General Tumour Biomarker and Contributes to the Development of Cutaneous Squamous Cell Carcinoma

Acta Dermato-Venereologica
ATP citrate lyase, the first rate-limiting enzyme in de novo lipogenesis, plays a crucial role in tumour progression. This study explores ATP citrate lyase’s potential as a tumour biomarker and its role in cutaneous squamous cell carcinoma.
Ruiting Luo, Yingjian Huang, Ruimin Bai, Meng Liu, Liang Sun, Xiaofei Wang, Yan Zheng   +6 more
doaj   +1 more source

Screening of alginate lyase-excreting microorganisms from the surface of brown algae

AMB Express, 2017
Alginate lyase is a biocatalyst that degrades alginate to produce oligosaccharides, which have many bioactive functions and could be used as renewable biofuels.
Mingpeng Wang, Lei Chen, Zhaojie Zhang, Xuejiang Wang, Song Qin, Peisheng Yan   +5 more
doaj   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

One-step purification and characterization of alginate lyase from a clinical Pseudomonas aeruginosa with destructive activity on bacterial biofilm [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Pseudomonas aeruginosais a Gram-negative and aerobic rod bacterium that displays mucoid and non-mucoid phenotype. Mucoid strains secrete alginate, which is the main agent of biofilms in chronic P. aeruginosa infections, show high resistance
Parinaz Ghadam, Fatemeh Akhlaghi, Ahya Abdi Ali   +2 more
doaj   +1 more source

Mechanism of Light Induced Radical Pair Formation in Coenzyme B₁₂-Dependent Ethanolamine Ammonia-Lyase

, 2018
Coenzyme B12 (adenosylcobalamin = AdoCbl)-dependent enzymes catalyze complex molecular transformations by employing radical chemistry. The initial step in the native catalytic cycle, upon substrate binding, involves homolytic cleavage of the Co–C bond of
Pawel M. Kozlowski (1285185), Maria Jaworska (1372770), Megan J. Toda (5284517), Abdullah Al Mamun (5489402), Piotr Lodowski (1372761)   +4 more
core   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Alginate Lyase from Indonesian Bacillus megaterium S245 Shows Activities Toward Polymannuronate and Polyguluronate

Squalen, 2017
Screening of alginate lyase producing bacteria associated with seaweed Sargassum crassifolium was carried out, and isolate S245, identified as Bacillus megaterium S245 was found to produce high alginate lyase activity.
Subaryono Subaryono, Yuwanita Ardilasari, Rosmawaty Peranginangin, Fransisca Rungkat Zakaria, Maggy Thenawidjaja Suhartono   +4 more
doaj   +1 more source

Biochemical Characterization of a Bifunctional Enzyme Constructed by the Fusion of a Glucuronan Lyase and a Chitinase from Trichoderma sp.

Life, 2020
Bifunctional enzymes created by the fusion of a glucuronan lyase (TrGL) and a chitinase (ThCHIT42) from Trichoderma sp. have been constructed with the aim to validate a proof of concept regarding the potential of the chimera lyase/hydrolase by analyzing ...
Zeineb Baklouti, Cédric Delattre, Guillaume Pierre, Christine Gardarin, Slim Abdelkafi, Philippe Michaud, Pascal Dubessay   +6 more
doaj   +1 more source

Phycobiliprotein Lyases [PDF]

, 2008
Phycobilins are light harvesting pigments of cyanobacteria and red algae. In cyanobacteria, four phycobiliproteins are organized in phycobilisomes: phycocyanin (PC), allophycocyanin (APC), and often also phycoerythrocyanin (PEC) or phycoerythrin (PE ...
Tu, Jun-Ming
core  

Catalytic Roles of Coenzyme Pyridoxal-5′-phosphate (PLP) in PLP-Dependent Enzymes: Reaction Pathway for Methionine-γ-Lyase-Catalyzed l‑Methionine Depletion

, 2020
Pyridoxal-5′-phosphate (PLP), the active form of vitamin B6, is an important and versatile coenzyme involved in a variety of enzymatic reactions, accounting for about 4% of all classified activities.
Yunsong Zhao, Chang-Guo Zhan, Yunsong Zhao (835374), Hai-Bin Luo (225984), Hai-Bin Luo, Zhe Li (219258), Zhe Li, Huifang Zhou, Huifang Zhou (5799005), Chang-Guo Zhan (147266)   +9 more
core   +1 more source