Results 81 to 90 of about 78,507 (251)

Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide

Infection and Immunity
Currently, most tools utilized in host-pathogen interaction studies depend on the use of human or mouse (Mus musculus) cells and tissues. While these species have led to countless breakthroughs in our understanding of infectious disease, there are ...
Christopher C. Wells, Tanja Petnicki-Ocwieja, Shumin Tan, Stephen C. Bunnell, Sam R. Telford, Linden T. Hu, Jeffrey S. Bourgeois   +6 more
doaj   +1 more source

Assessment of Borrelia miyamotoi in febrile patients and ticks in Alsace, an endemic area for Lyme borreliosis in France

Parasites & Vectors, 2020
Background Borrelia miyamotoi is a relapsing fever Borrelia species transmitted by ticks of the Ixodes ricinus complex. Human disease caused by B. miyamotoi was first described in Russia and later in the USA and Japan.
Pierre H. Boyer, Joris Koetsveld, Laurence Zilliox, Hein Sprong, Émilie Talagrand-Reboul, Yves Hansmann, Sylvie Josiane de Martino, Nathalie Boulanger, Joppe W. Hovius, Benoît Jaulhac   +9 more
doaj   +1 more source

Protective Immunity and New Vaccines for Lyme Disease

Clinical Infectious Diseases, 2019
Lyme disease, caused by some Borrelia burgdorferi sensu lato, is the most common tick-borne illness in the Northern Hemisphere and the number of cases, and geographic spread, continue to grow. Previously identified B.
M. Gomes-Solecki, P. Arnaboldi, P. B. Backenson, J. Benach, C. Cooper, R. Dattwyler, M. Diuk-Wasser, E. Fikrig, J. Hovius, W. Laegreid, U. Lundberg, R. Marconi, A. Marques, P. Molloy, S. Narasimhan, U. Pal, João H. F. Pedra, S. Plotkin, D. Rock, P. Rosa, S. Telford, J. Tsao, X. F. Yang, S. Schutzer   +23 more
semanticscholar   +1 more source

Growth and age differences between two male alternative reproductive tactics in the plainfin midshipman

Journal of Fish Biology, EarlyView.
Abstract The plainfin midshipman (Porichthys notatus Girard, 1854) is a toadfish with two distinct reproductive male tactics: ‘guarder males’ and ‘sneaker males’. These two tactics are anatomically, physiologically and behaviourally distinct from one another at sexual maturity, but it remained unclear whether these two male types remain fixed or ...
Micah J. Quindazzi, Angus Townsend, Aneesh P. H. Bose, Sigal Balshine, Francis Juanes   +4 more
wiley   +1 more source

Exploring user experiences of the National Institute of Health and Care Excellence’s Shared Decision Making learning package: an online qualitative study

BMJ Open
Objective To evaluate the user experience of the joint National Institute of Health and Care Excellence (NICE)/Keele University Shared Decision Making (SDM) learning package.Design A qualitative study using online semistructured interviews.
Jonathan Underhill, Neal Maskrey, Simon Jacklin, Jessica Thompson, Andy Hutchinson, Katie Maddock, Laura Norburn   +6 more
doaj   +1 more source

Protein engineering strategies to optimise recombinant product synthesis and accumulation in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
Summary In plant molecular farming, recombinant products include traditional protein targets, such as antibodies, antigens, and enzymes, but also increasingly refers to high‐value peptides, and small molecules produced by heterologous enzymatic pathways.
Maxim D. Harding, Frank Sainsbury
wiley   +1 more source

Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group

Antibiotics, 2019
Objective: Chronic Lyme disease has been a poorly defined term and often dismissed as a fictitious entity. In this paper, the International Lyme and Associated Diseases Society (ILADS) provides its evidence-based definition of chronic Lyme disease ...
S. Shor, C. Green, Beatrice M Szantyr, S. Phillips, K. Liegner, J. Burrascano, R. Bransfield, Elizabeth L. Maloney   +7 more
semanticscholar   +1 more source

Registered Nurses' Knowledge, Attitudes, and Practices Toward Climate‐Sensitive Vector‐Borne Diseases: Findings From a Cross‐Sectional Survey

Public Health Nursing, EarlyView.
ABSTRACT Objective Climate change is contributing to increasing rates of vector‐borne diseases, affecting global population health. As the largest group of regulated health professionals, nurses play an integral role in climate‐related health challenges.
Shannon Y. Vandenberg, Tracy Oosterbroek, Andrea Chircop, Peter Kellett   +3 more
wiley   +1 more source

Gene-based therapies for hemophilia

Research and Practice in Thrombosis and Haemostasis
Gene therapy is a transformative approach to treating genetic disorders in order to improve disease outcomes for patients. Hemophilia A and B are inherited genetic disorders caused by mutations in the FVIII and FIX genes, respectively.
Melissa F. Glasner, Steven Pipe, Wolfgang Miesbach   +2 more
doaj   +1 more source

What is the real number of Lyme disease cases in Canada?

BMC Public Health, 2019
BackgroundLyme disease is emerging in Canada due to expansion of the range of the tick vector Ixodes scapularis from the United States. National surveillance for human Lyme disease cases began in Canada in 2009.
N. Ogden, C. Bouchard, J. Badcock, M. Drebot, S. Elias, T. Hatchette, J. Koffi, P. Leighton, L. R. Lindsay, C. Lubelczyk, A. Peregrine, Robert P. Smith, D. Webster   +12 more
semanticscholar   +1 more source