Results 101 to 110 of about 86,084 (267)

The Controversies, Challenges and Complexities of Lyme Disease: A Narrative Review

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2018
Purpose: Lyme disease has become an increasingly important global public health concern. Method: A narrative review was conducted and designed to present a broad perspective on Lyme disease, and describe its history and development in terms of clinical ...
Marie Claire Van Hout
doaj   +1 more source

The Epidemiology of Primary Lateral Sclerosis: Results from a Population‐Based Cohort

open access: yesAnnals of Neurology, Volume 99, Issue 3, Page 606-613, March 2026.
Objective In this population‐based study, we described the epidemiology of primary lateral sclerosis (PLS) in northern Italy and compared the clinical characteristics of patients with PLS to those with predominant upper motor neuron (PUMN) involvement and classic amyotrophic lateral sclerosis (ALS).
Rosario Vasta   +17 more
wiley   +1 more source

A Case Series of Hypermucoid Klebsiella pneumoniae Liver Abscess in Caucasian Americans Without Travel History: An Epidemiologic Shift?

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Hypervirulent Klebsiella pneumoniae (hvKp) is an emerging cause of community‐acquired pyogenic liver abscess (PLA), classically described in East and Southeast Asia. We report two cases of hvKp‐associated PLA in Caucasian women of American origin with no history of international travel, animal exposure, or Asian food consumption. Both patients
Krishna Sai Kiran Sakalabaktula   +6 more
wiley   +1 more source

Lyme disease vaccine [PDF]

open access: yesPaediatrics & Child Health, 2000
Lyme disease is the most common tick-borne infection in the United States, with more than 12,000 cases reported annually (1). The disease is characterized by a rash (erythema migrans) and various systemic (nervous, cardiac and musculoskeletal) manifestations; clinical manifestations of Lyme disease were reviewed recently (2). Most cases of Lyme disease
openaire   +5 more sources

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu   +9 more
wiley   +1 more source

Lyme Disease and the Workplace [PDF]

open access: yes, 2019
{Excerpt] Lyme disease, an infection by the bacterium Borrelia burgdorferi, was named after a Connecticut town where a group of arthritis cases in children appeared in the early 1970s.
Brown, Nellie J
core   +1 more source

Remodeling the Inflammatory Microenvironment: Nanomaterial‐Based Targeted Strategies for Systemic Lupus Erythematosus and Lupus Nephritis

open access: yesSmall Science, Volume 6, Issue 3, March 2026.
Current treatments for severe lupus nephritis are limited by side effects due to poor drug targeting. This review explores how smart nanomaterials—like liposomes and biomimetic carriers—can precisely deliver drugs to overactive immune cells and the kidneys. These nanotherapeutics enhance efficacy, reduce toxicity, and enable combination strategies. The
Cheng Zhou   +6 more
wiley   +1 more source

Host glycosylation of immunoglobulins impairs the immune response to acute Lyme diseaseResearch in context

open access: yesEBioMedicine
Summary: Background: Lyme disease is caused by the bacteria Borreliella burgdorferi sensu lato (Bb) transmitted to humans from the bite of an infected Ixodes tick.
Benjamin S. Haslund-Gourley   +7 more
doaj   +1 more source

Hypersensitivity to Ticks and Lyme Disease Risk

open access: yesEmerging Infectious Diseases, 2005
Although residents of Lyme disease–endemic regions describe frequent exposure to ticks, Lyme disease develops in relatively few. To determine whether people who experience cutaneous hypersensitivity against tick bite have fewer episodes of Lyme disease ...
Georgine Burke   +5 more
doaj   +1 more source

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