Results 101 to 110 of about 9,292,932 (291)

Direct Diagnostic Tests for Lyme Disease

open access: yesClinical Infectious Diseases, 2018
Borrelia burgdorferi was discovered to be the cause of Lyme disease in 1983, leading to seroassays. The 1994 serodiagnostic testing guidelines predated a full understanding of key B. burgdorferi antigens and have a number of shortcomings. These serologic
S. Schutzer   +26 more
semanticscholar   +1 more source

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

open access: yesImmunology, EarlyView.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco   +24 more
wiley   +1 more source

Examining Infant and Child Neurodevelopmental Outcomes After Lyme Disease During Pregnancy

open access: yesPathogens
Lyme disease is the most common vector-borne disease in the United States. Recent environmental and socioecological changes have led to an increased incidence of Lyme and other tick-borne diseases, which enhances the urgency of identifying and mitigating
Meagan E. Williams   +3 more
doaj   +1 more source

Lyme Borreliosis During Pregnancy [PDF]

open access: yes, 2012
One of the authors (AL) presented a poster on 34 pregnancies of maternal Lyme borreliosis (Lb) in 1995. It was striking that untreated Lb associated with higher probability of adverse outcome but the number of patients were small and the statistical ...
Andrá, Norbert Solymosi
core   +2 more sources

Misdiagnosis of Lyme Disease With Unnecessary Antimicrobial Treatment Characterizes Patients Referred to an Academic Infectious Diseases Clinic

open access: yesOpen Forum Infectious Diseases, 2019
Background Although Lyme disease is the most common vector-borne infection in the United States, diagnostic accuracy within community settings is not well characterized.
Takaaki Kobayashi   +8 more
semanticscholar   +1 more source

Severe Hyperbilirubinemia: A Rare Complication of Lyme Disease

open access: yesCase Reports in Gastrointestinal Medicine, 2019
Gastrointestinal signs and symptoms are common in the early stages of Lyme disease. However, hyperbilirubinemia from Lyme disease is extremely uncommon. There are only two case reports in literature attributing Lyme disease to hyperbilirubinemia. Here we
Maarij Baig, Lin Zheng, Alka Farmer
doaj   +1 more source

Analyzing the Potential Risk of Climate Change on Lyme Disease in Eastern Ontario, Canada Using Time Series Remotely Sensed Temperature Data and Tick Population Modelling

open access: yesRemote Sensing, 2017
The number of Lyme disease cases (Lyme borreliosis) in Ontario, Canada has increased over the last decade, and that figure is projected to continue to increase.
Angela Cheng   +5 more
doaj   +1 more source

Protein engineering strategies to optimise recombinant product synthesis and accumulation in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary In plant molecular farming, recombinant products include traditional protein targets, such as antibodies, antigens, and enzymes, but also increasingly refers to high‐value peptides, and small molecules produced by heterologous enzymatic pathways.
Maxim D. Harding, Frank Sainsbury
wiley   +1 more source

The Controversies, Challenges and Complexities of Lyme Disease: A Narrative Review

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2018
Purpose: Lyme disease has become an increasingly important global public health concern. Method: A narrative review was conducted and designed to present a broad perspective on Lyme disease, and describe its history and development in terms of clinical ...
Marie Claire Van Hout
doaj   +1 more source

Antibody-resistant mutants of Borrelia burgdorferi: in vitro selection and characterization. [PDF]

open access: yes, 1992
We used polyclonal antisera and monoclonal antibodies (mAbs) to inhibit the growth of clonal populations of two strains of Borrelia burgdorferi, the Lyme disease agent, and thereby select for antibody-resistant mutants.
Barbour, AG   +4 more
core  

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