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Lyme Disease [PDF]

open access: yesClinical Infectious Diseases, 2000
Lyme disease, which is caused by Borrelia burgdorferi and transmitted in the United States primarily by Ixodes scapularis (the deer tick), is the most common vector borne disease in the United States. Its most frequent manifestation, a characteristic, expanding annular rash (erythema migrans), sometimes accompanied by myalgia, arthralgia, and malaise ...
E D, Shapiro, M A, Gerber
openaire   +2 more sources

Outpatient visits before and after Lyme disease diagnosis in a Maryland employer-based health plan

open access: yesBMC Health Services Research, 2023
Background Insurance claims data have been used to inform an understanding of Lyme disease epidemiology and cost of care, however few such studies have incorporated post-treatment symptoms following diagnosis.
Alison W. Rebman   +6 more
doaj   +1 more source

The utility of “Google Trends” for epidemiological research: Lyme disease as an example

open access: yesGeospatial Health, 2010
Internet search engines have become an increasingly popular resource for accessing health-related information. The key words used as well as the number and geographic location of searches can provide trend data, as have recently been made available by ...
Ari Seifter   +3 more
doaj   +1 more source

Antimicrobial Activity of Bee Venom and Melittin against Borrelia burgdorferi

open access: yesAntibiotics, 2017
Lyme disease is a tick-borne, multi-systemic disease, caused by the bacterium Borrelia burgdorferi. Though antibiotics are used as a primary treatment, relapse often occurs after the discontinuation of antimicrobial agents. The reason for relapse remains
Kayla M. Socarras   +4 more
doaj   +1 more source

A diagnostic classifier for gene expression-based identification of early Lyme disease

open access: yesCommunications Medicine, 2022
Servellita et al. develop a machine learning-based classifier to diagnose Lyme disease using gene expression data. The classifier achieves high sensitivity for early infections, even prior to positivity on antibody testing.
Venice Servellita   +13 more
doaj   +1 more source

Epidemiology and clinical manifestations of reported Lyme disease cases: Data from the Canadian Lyme disease enhanced surveillance system.

open access: yesPLoS ONE, 2023
Lyme disease cases reported in seven Canadian provinces from 2009 to 2019 through the Lyme Disease Enhanced Surveillance System are described herein by demographic, geography, time and season. The proportion of males was greater than females.
Kiera Murison   +7 more
doaj   +1 more source

Seasonality of Acute Lyme Disease in Children

open access: yesTropical Medicine and Infectious Disease, 2021
Due to the life cycle of its vector, Lyme disease has known seasonal variation. However, investigations focused on children have been limited. Our objective was to evaluate the seasonality of pediatric Lyme disease in three endemic regions in the United ...
Kathryn M. Sundheim   +8 more
doaj   +1 more source

The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease

open access: yesJournal of Clinical Microbiology
There are nearly 500,000 cases of Lyme disease each year in the United States; 10%–20% of them result in the development of a debilitating chronic disease known as post-treatment Lyme disease.
Anna F. Hickman   +3 more
doaj   +1 more source

Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide

open access: yesInfection and Immunity
Currently, most tools utilized in host-pathogen interaction studies depend on the use of human or mouse (Mus musculus) cells and tissues. While these species have led to countless breakthroughs in our understanding of infectious disease, there are ...
Christopher C. Wells   +6 more
doaj   +1 more source

Risk of post-treatment Lyme disease in patients with ideally-treated early Lyme disease: A prospective cohort study.

open access: yesInternational Journal of Infectious Diseases, 2022
Purpose: Post-treatment Lyme disease (PTLD) is characterized by patient-reported symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was to assess whether participants with a history of Lyme disease (LD) would be ...
John N. Aucott   +5 more
doaj   +1 more source

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