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Lyme Disease [PDF]

open access: yesClinics in Laboratory Medicine, 2010
Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States. The clinical presentation varies depending on the stage of the illness: early disease includes erthyma migrans, early disseminated disease includes multiple erythema migrans, meningitis, cranial nerve palsies, and carditis; late ...
Thomas S, Murray, Eugene D, Shapiro
openaire   +2 more sources

The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease

open access: yesJournal of Clinical Microbiology
There are nearly 500,000 cases of Lyme disease each year in the United States; 10%–20% of them result in the development of a debilitating chronic disease known as post-treatment Lyme disease.
Anna F. Hickman   +3 more
doaj   +1 more source

Antiphospholipid antibodies in acute and post-treatment Lyme disease

open access: yesInfection and Immunity
Acute Lyme disease is caused by a Borrelia infection and typically responds to antibiotic treatment, but post-infectious chronic symptoms are common. The precise origin of these post-treatment symptoms is unknown; dysregulation of immune responses raised
Muskan Shrestha   +10 more
doaj   +1 more source

Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide

open access: yesInfection and Immunity
Currently, most tools utilized in host-pathogen interaction studies depend on the use of human or mouse (Mus musculus) cells and tissues. While these species have led to countless breakthroughs in our understanding of infectious disease, there are ...
Christopher C. Wells   +6 more
doaj   +1 more source

Common Neurologic Features of Lyme Disease That May Present to a Rheumatologist

open access: yesPathogens, 2023
Lyme disease, caused by Borrelia burgdorferi (Bb) infection, has a broad spectrum of clinical manifestations and severity. Patients with possible Lyme disease may seek out or be referred to rheumatologists.
Swati Govil   +5 more
doaj   +1 more source

The impact of Pandemic COVID-19 on cases of Borreliosis infection in 2020

open access: yesJournal of Education, Health and Sport, 2021
Borreliosis (Lyme borreliosis; Lyme disease) is a zoonotic disease caused by spirochetes from the genus Borrelia. In humans, the accidental host of ticks, the infection is transmitted by the bite of the tick - the spirochetes are present in the salivary
Karolina Rogulska   +2 more
doaj   +1 more source

Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann   +3 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Lyme Disease Biobank: 10 years of 3 month follow-up visits from 2014 to 2023

open access: yesFrontiers in Medicine
IntroductionLyme Disease Biobank (LDB) enrolls participants with signs and symptoms of early Lyme disease (LD) from endemic areas and makes samples available to researchers developing more accurate diagnostics. From 2014 to 23, 466 cases and 367 controls
Elizabeth J. Horn   +7 more
doaj   +1 more source

Point‐of‐Care Ultrasound for the Diagnosis of Hip Effusion in Children Presenting to the Emergency Department With Atraumatic Limp or Hip Pain: A Scoping Review

open access: yesJournal of Ultrasound in Medicine, EarlyView.
This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan   +3 more
wiley   +1 more source

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