Myositis Autoantibodies in Patients with Suspected Post-Treatment Lyme Disease Syndrome [PDF]
Life, 2023 Most patients suffering from Lyme disease are effectively treated with antibiotics. In some patients, however, problems persist for a long time despite appropriate therapy.
Kristyna Sloupenska +10 more
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Seroprevalence of Antibodies against Tick-Borne Pathogens in Czech Patients with Suspected Post-Treatment Lyme Disease Syndrome [PDF]
Microorganisms, 2021 The hypothesized importance of coinfections in the pathogenesis of post-treatment Lyme disease syndrome (PTLDS) leads to the use of combined, ongoing antimicrobial treatment in many cases despite the absence of symptoms typical of the presence of ...
Kristyna Sloupenska +9 more
doaj +4 more sources
International Journal of Infectious Diseases, 2022 Purpose: Post-treatment Lyme disease (PTLD) is characterized by patient-reported symptoms after treatment for Borrelia burgdorferi infection. The primary aim of this study was to assess whether participants with a history of Lyme disease (LD) would be ...
John N. Aucott +5 more
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Antiphospholipid antibodies in acute and post-treatment Lyme disease [PDF]
Infection and ImmunityAcute Lyme disease is caused by a Borrelia infection and typically responds to antibiotic treatment, but post-infectious chronic symptoms are common. The precise origin of these post-treatment symptoms is unknown; dysregulation of immune responses raised
Muskan Shrestha +10 more
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Post-treatment Lyme Disease as a Model for Persistent Symptoms in Lyme Disease [PDF]
Frontiers in Medicine, 2020 It has long been observed in clinical practice that a subset of patients with Lyme disease report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal pain, which may last for a significant period of time.
Alison W. Rebman, John N. Aucott
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Neuroborreliosis and Post-Treatment Lyme Disease Syndrome: Focus on Children [PDF]
Life, 2023 Neuroborreliosis is a form of Lyme Borreliosis (LB) that affects various structures of the central and peripheral nervous system. Although most cases of LB can be cured with a course of antibiotics, some children can present prolonged symptoms, which may
Agnieszka Myszkowska-Torz +5 more
doaj +2 more sources
Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome? [PDF]
Frontiers in NeurologyDysautonomia, or dysfunction of the autonomic nervous system (ANS), may occur following an infectious insult and can result in a variety of debilitating, widespread, and often poorly recognized symptoms.
Brittany L. Adler +3 more
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Post-Treatment Lyme Disease Syndrome in Six European Countries Using Data from the Burden of Lyme Disease (BOLD) Study [PDF]
PathogensUp to 10% of patients with Lyme borreliosis (LB) will experience symptoms that fulfill the Infectious Disease Society of America (IDSA) criteria of post-treatment Lyme disease syndrome (PTLDS).
Holly Yu +14 more
doaj +2 more sources
Annexin A2 antibodies in post-treatment Lyme disease [PDF]
Therapeutic Advances in Infectious DiseaseBackground: Anti-annexin A2 (AA2) antibodies have been described in Lyme arthritis and erythema migrans, although they have not been described in post-treatment Lyme disease (PTLD).
John B. Miller +5 more
doaj +2 more sources
Efficacy of Short-Term High Dose Pulsed Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-Infections: A Report of Three Cases and Literature Review [PDF]
Antibiotics, 2022 Lyme disease and associated co-infections are increasing worldwide and approximately 20% of individuals develop chronic Lyme disease (CLD)/Post-Treatment Lyme Disease Syndrome (PTLDS) despite early antibiotics.
Richard I. Horowitz, Phyllis R. Freeman
doaj +2 more sources