Results 1 to 10 of about 26,337 (144)

Post-treatment Lyme Disease as a Model for Persistent Symptoms in Lyme Disease. [PDF]

Front Med (Lausanne), 2020
It has long been observed in clinical practice that a subset of patients with Lyme disease report a constellation of symptoms such as fatigue, cognitive difficulties, and musculoskeletal pain, which may last for a significant period of time. These symptoms, which can range from mild to severe, have been reported throughout the literature in both ...
Rebman AW, Aucott JN.
europepmc   +6 more sources

Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the U.S. with administrative claims data. [PDF]

EBioMedicine, 2023
Post-treatment Lyme disease syndrome (PTLDS) is used to describe Lyme disease patients who have the infection cleared by antibiotic but then experienced persisting symptoms of pain, fatigue, or cognitive impairment. Currently, little is known about the cause or epidemiology of PTLDS.We conducted a data-driven study with a large nationwide ...
Chung MK, Caboni M, Strandwitz P, D'Onofrio A, Lewis K, Patel CJ.   +5 more
europepmc   +4 more sources

Myositis Autoantibodies in Patients with Suspected Post-Treatment Lyme Disease Syndrome. [PDF]

Life (Basel), 2023
Most patients suffering from Lyme disease are effectively treated with antibiotics. In some patients, however, problems persist for a long time despite appropriate therapy. The term post-treatment Lyme disease syndrome (PTLDS) is currently used for this condition in scientific literature.
Sloupenska K, Koubkova B, Horak P, Hutyrova B, Racansky M, Mares J, Miklusova M, Schovanek J, Zapletalova J, Raska M, Krupka M.   +10 more
europepmc   +5 more sources

Dysautonomia following Lyme disease: a key component of post-treatment Lyme disease syndrome? [PDF]

Front Neurol
Dysautonomia, or dysfunction of the autonomic nervous system (ANS), may occur following an infectious insult and can result in a variety of debilitating, widespread, and often poorly recognized symptoms. Dysautonomia is now widely accepted as a complication of COVID-19 and is an important component of Post-Acute Sequelae of COVID-19 (PASC or long COVID)
Adler BL, Chung T, Rowe PC, Aucott J.
europepmc   +5 more sources

Treatment of post-treatment Lyme disease symptoms-a systematic review. [PDF]

Eur J Neurol
AbstractBackground and purposeResidual symptoms after treatment of Lyme disease, sometimes called post‐treatment Lyme disease symptoms (PTLDs), are a matter of ongoing controversy. To guide treatment recommendations, a systematic review was performed of the available literature on specific treatment for PTLDs.MethodsA systematic literature search of ...
Dersch R, Torbahn G, Rauer S.
europepmc   +5 more sources

Update of the Swiss guidelines on post-treatment Lyme disease syndrome. [PDF]

Swiss Medical Weekly, 2016
Lyme borreliosis is caused by Borrelia burgdorferi sensu lato infection, which responds well to antibiotic therapy in the overwhelming majority of cases.
C Strahm, D Nadal, E Altpeter, E Bernasconi, H Furrer, J Delaloye, J Nemeth, M Abbas, M Sturzenegger, R Weber, S Erb, S Zimmerli, T Kuntzer, the for, U Heininger   +14 more
core   +13 more sources

Autoantibodies in post-treatment Lyme disease syndrome. [PDF]

Front Neurol, 2022
Alaedini A, Wormser GP.
europepmc   +4 more sources

Lyme Disease and Post-treatment Lyme Disease Syndrome: Current and Developing Treatment Options. [PDF]

Cureus, 2023
Lyme disease and its treatment implications have become an ever-increasing area of concern within the United States related to the markedly increased prevalence of infection within the last two decades. The presentation, pathophysiology, and epidemiology of Lyme disease have been well studied, and thus treatments for this disease are widely available ...
Talbot NC, Spillers NJ, Luther P, Flanagan C, Soileau LG, Ahmadzadeh S, Viswanath O, Varrassi G, Shekoohi S, Cornett EM, Kaye AM, Kaye AD.   +11 more
europepmc   +3 more sources

Gene set predictor for post-treatment Lyme disease. [PDF]

Cell Rep Med, 2022
Lyme disease (LD) is tick-borne disease whose post-treatment sequelae are not well understood. For this study, we enrolled 152 individuals with symptoms of post-treatment LD (PTLD) to profile their peripheral blood mononuclear cells (PBMCs) with RNA sequencing (RNA-seq).
Clarke DJB, Rebman AW, Fan J, Soloski MJ, Aucott JN, Ma'ayan A.   +5 more
europepmc   +3 more sources

Neuroborreliosis and Post-Treatment Lyme Disease Syndrome: Focus on Children. [PDF]

Life (Basel), 2023
Neuroborreliosis is a form of Lyme Borreliosis (LB) that affects various structures of the central and peripheral nervous system. Although most cases of LB can be cured with a course of antibiotics, some children can present prolonged symptoms, which may constitute post-treatment Lyme disease syndrome (PTLDS).
Myszkowska-Torz A, Frydrychowicz M, Tomaszewski M, Figlerowicz M, Mania A, Mazur-Melewska K.   +5 more
europepmc   +4 more sources