Results 31 to 40 of about 26,337 (144)

Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]

, 2008
Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Aguero-Rosenfeld ME, Aguero-Rosenfeld ME, Aguero-Rosenfeld ME, Bacon RM, Bettina Wilske, Bono JL, Bruckbauer HR, Christina Ambros-Rudolph, Coleman JL, Dressler F, Engstrom SM, Feder, Fung BP, Glatz M, Goettner G, Grodzicki RL, Guo BP, Hansen K, Hauser U, Helmut Kerl, Hofmann H, Hulshof MM, Jauris-Heipke S, Kalish RA, Lahdenne P, Lebech AM, Ledue TB, Liang FT, Liang FT, Magnarelli LA, Magnarelli LA, Marangoni A, Martin Glatz, Massarotti EM, Mullegger RR, Peltomaa M, Philipp MT, Picken MM, Plorer A, Rasiah C, Robert R. Müllegger, Roessler D, Ruzic-Sabljic E, Ryffel K, Shadick NA, Sillanpaa H, Simpson WJ, Smith RP, Stanek G, Stanek G, Volker Fingerle, Volkman DJ, Wilske B, Wilske B, Wilske B, Wilske B, Wormser GP, Zhang JR   +57 more
core   +1 more source

What Makes It Tick: Exploring the Mechanisms of Post-treatment Lyme Disease Syndrome. [PDF]

Cureus
Post-treatment Lyme disease syndrome (PTLDS), which may also be referred to incorrectly as "chronic Lyme disease," is defined by the Infectious Diseases Society of America (IDSA) as the presence of fatigue, pain, and/or cognitive complaints with the functional impact that persists for more than six months after completing treatment for Lyme disease (LD)
Wester KE, Nwokeabia BC, Hassan R, Dunphy T, Osondu M, Wonders C, Khaja M.   +6 more
europepmc   +3 more sources

Association of small fiber neuropathy and post treatment Lyme disease syndrome. [PDF]

PLoS One, 2019
To examine whether post-treatment Lyme disease syndrome (PTLDS) defined by fatigue, cognitive complaints and widespread pain following the treatment of Lyme disease is associated with small fiber neuropathy (SFN) manifesting as autonomic and sensory dysfunction.This single center, retrospective study evaluated subjects with PTLDS.
Novak P, Felsenstein D, Mao C, Octavien NR, Zubcevik N.   +4 more
europepmc   +5 more sources

Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. [PDF]

, 2020
Lyme disease is one of most common vector-borne diseases, reporting more than 300,000 cases annually in the United States. Treating Lyme disease during its initial stages with traditional tetracycline antibiotics is effective. However, 10-20% of patients
Ahmed, Mohamed Sohail, Ambati, Aditya, Inayathullah, Mohammed, Mallajosyula, Venkata Vamsee Aditya, Pothineni, Venkata Raveendra, Potula, Hari-Hara SK, Rajadas, Jayakumar, Sridharan, Brindha   +7 more
core  

Effects of intravenous ketamine in a patient with post-treatment Lyme disease syndrome. [PDF]

Int Med Case Rep J, 2017
Post-treatment Lyme disease syndrome (PTLDS) is a pain disorder for which there remains no gold standard treatment option. Here, we report a case of PTLDS in a female patient whose pain was refractory to treatment options such as radiofrequency ablation, vitamin infusion therapy, opioid analgesics, and other pharmacotherapies.
Hanna AF, Abraham B, Hanna A, Smith AJ.
europepmc   +4 more sources

The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]

, 2015
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Adam Dyer, Albrecht, Bagos, Barcena-Uribarri, Behera, Bhide, Bordier, Brooks, Bunikis, Cabello, Casjens, Coutte, Crago, Crother, Cullen, Di, Dietrich, Eddy, Eswar, Fairman, Feng, Finn, Fraser, Freeman, Gemma Brown, Gessmann, Greene, Guina, Heffernan, Hong, Jaroszewski, Kenedy, Koebnik, Kopp, Kraiczy, Kurtenbach, Lenhart, Lenka Stejskal, Livengood, Margos, Mertins, Mittal, Nair, Oksi, Ornstein, Ostberg, Paetzel, Pautsch, Petersen, Peter R. Laity, Pettersen, Prasadarao, Preac-Mursic, Pugsley, Pulzova, Richard J. Bingham, Robert, Rogovskyy, Schmidli, Schulz, Setubal, Skare, Sperisen, Steere, Struyve, Sugawara, Svergun, Tamm, Thein, Tilly, Tommassen, Vogt, Volkov, Xie, Yamashita, Yang, Zhang   +76 more
core   +1 more source

The effectiveness of public health interventions to reduce the health impact of climate change:a systematic review of systematic reviews [PDF]

, 2013
Climate change is likely to be one of the most important threats to public health in the coming years. Yet despite the large number of papers considering the health impact of climate change, few have considered what public health interventions may be of ...
A Bouchama, A Croft, AJ McMichael, BF Arnold, BR Murphy, C Baker-Austin, C Gamble, C Heintze, C Savage, CE Lawrance, D Kay, D Zmirou, DE Bowler, DJ Rogers, E Esu, EN Naumova, FC Curriero, FO ter Kuile, G Nichols, GA Romero, GH Guyatt, H Balshem, H Nakato, H Paerl, HL Risebro, HW Choi, HY Richardson, IR Lake, IR Lake, J Carmona-Fonseca, J Keiser, JC Semenza, K Ohtomo, KK Ballenger-Browning, KL Bassil, L Fewtrell, Lee Hooper, M Hashizume, M Hashizume, MA Luque Fernandez, Maha Bouzid, MK van Aalst, Monica da Silva Nunes, MS Islam, N Al-Muhandis, N Siva, P Reiter, Paul R. Hunter, PM Graves, PR Hunter, PR Hunter, PR Hunter, PR Hunter, RF Baggaley, RM Elliott, RS Kovats, RS Kovats, RS Kovats, S Gundry, S Paz, S Warshafsky, SE Hrudey, T Clasen, TE Erlanger, TP Eisele, V Abrahamson, WP Schmidt, X Wang   +67 more
core   +3 more sources

Post-treatment Lyme disease symptoms score: Developing a new tool for research. [PDF]

PLoS One, 2019
Some patients have residual non-specific symptoms after therapy for Lyme disease, referred to as post-treatment Lyme disease symptoms or syndrome, depending on whether there is functional impairment. A standardized test battery was used to characterize a diverse group of Lyme disease patients with and without residual symptoms.
Turk SP, Lumbard K, Liepshutz K, Williams C, Hu L, Dardick K, Wormser GP, Norville J, Scavarda C, McKenna D, Follmann D, Marques A.   +11 more
europepmc   +5 more sources

Guidelines for Lyme borreliosis: post-treatment Lyme disease syndrome (PTLDS)

Infectious Diseases Now
Persistent symptoms following appropriate treatment of confirmed Lyme borreliosis (LB) require a systematic clinical reassessment. The diagnostic approach should verify the accuracy of the initial diagnosis, adherence to and adequacy of antibiotic therapy, and consider potential sequelae or differential diagnoses such as new-onset diseases or ...
P. Arias, X. Gocko, F. Roblot, Y. Hansmann, E. Baux, C. Eldin, S. Nguala, A. Gautier, C. Lemogne, A. Raffetin   +9 more
openaire   +2 more sources

The Emerging Role of Microbial Biofilm in Lyme Neuroborreliosis [PDF]

, 2018
Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia, respectively.
Bordignon, Valentina, Cavallo, Ilaria, D'Agosto, Giovanna, Di Domenico, Enea Gino, Ensoli, Fabrizio, Gallo, Maria Teresa, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Toma, Luigi, Trento, Elisabetta   +10 more
core   +2 more sources