Results 61 to 70 of about 77,574 (220)

Attention‐deficit hyperactivity disorder in children and young persons during the COVID‐19 pandemic. A temporal trends analysis of electronic heath records in Greater Manchester, England

JCPP Advances, EarlyView.
Abstract Background The incidence of attention‐deficit hyperactivity disorder (ADHD) in children and young people has increased in recent years. Disease frequency varies according to sociodemographic characteristics. There are seasonal patterns in ADHD diagnosis and prescribing with rates falling during school holidays.
Louise Hussey, Evangelos Kontopantelis, Pearl L. H. Mok, Darren M. Ashcroft, Shruti Garg, Carolyn A. Chew‐Graham, Karina Lovell, Roger T. Webb   +7 more
wiley   +1 more source

Aberrant T-cell phenotypes in a cohort of patients with post-treatment Lyme disease

Frontiers in Immunology
Post-treatment Lyme Disease (PTLD) is a poorly understood complication of Borrelia burgdorferi infection with significant patient morbidity. Characterized by fatigue, generalized myalgias, and cognitive impairment, PTLD symptomatology closely resembles ...
Alexander A. Girgis, Alexander A. Girgis, Raffaello Cimbro, Ting Yang, Alison W. Rebman, Thelio Sewell, Daniela Villegas de Flores, Aarti Vadalia, William H. Robinson, William H. Robinson, Andrea L. Cox, Erika Darrah, Mark J. Soloski, John Aucott   +13 more
doaj   +1 more source

Modified two-tiered testing algorithm for Lyme disease serology: the Canadian context

Canada Communicable Disease Report, 2020
Background: Lyme disease (LD) is emerging in many parts of central and eastern Canada. Serological testing is most commonly used to support laboratory diagnosis of LD.
Todd Hatchette, Robbin Lindsay, on behalf of the Lyme Disease Diagnostics Working Group   +2 more
doaj   +1 more source

In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]

, 2018
BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya, Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, Kwang-Min, Maguire, Peter, Parekh, Mansi B, Pothineni, Venkata Raveendra, Potula, Hari-Hara Sk, Rajadas, Jayakumar, Tayebi, Lobat   +9 more
core  

Point‐of‐Care Ultrasound for the Diagnosis of Hip Effusion in Children Presenting to the Emergency Department With Atraumatic Limp or Hip Pain: A Scoping Review

Journal of Ultrasound in Medicine, EarlyView.
This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan, David J. McCreary, Adriana Nedyalkova, Peter J. Snelling   +3 more
wiley   +1 more source

A sex-based analysis of complete blood count features during acute, untreated Lyme disease

Frontiers in Medicine
IntroductionAlthough lymphopenia has been described in acute Lyme disease (LD), the complete blood count (CBC) has not been comprehensively examined, nor have sex-based analyses been conducted. We analyzed CBC values and identified sex-based trends among
Alison W. Rebman, Ting Yang, Jonathan M. Zenilman, Mark J. Soloski, John N. Aucott   +4 more
doaj   +1 more source

Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Lichen sclerosus (LSc) is a chronic inflammatory dermatosis that primarily affects the genitalia. Growing evidence supports chronic occlusive urine exposure as the principal pathogenic driver, though other mechanisms, including mechanical irritation, hormonal influences, autoimmunity, and infection, have been proposed.
Liang Zhi Wong, Richard Watchorn, Sandra Jerkovic Gulin, Christopher B. Bunker, Georgios Kravvas   +4 more
wiley   +1 more source

Evidence for the Presence of Borrelia burgdorferi Biofilm in Infected Mouse Heart Tissues

Microorganisms
Borrelia burgdorferi, the bacterium responsible for Lyme disease, has been shown to form antimicrobial-tolerant biofilms, which protect it from unfavorable conditions.
Sahaja Thippani, Niraj Jatin Patel, Jasmine Jathan, Kate Filush, Kayla M. Socarras, Jessica DiLorenzo, Kunthavai Balasubramanian, Khusali Gupta, Geneve Ortiz Aleman, Jay M. Pandya, Venkata V. Kavitapu, Daina Zeng, Jennifer C. Miller, Eva Sapi   +13 more
doaj   +1 more source

Pediatric Lyme Disease Biobank, United States, 2015–2020

Emerging Infectious Diseases, 2020
In 2015, we founded Pedi Lyme Net, a pediatric Lyme disease research network comprising 8 emergency departments in the United States. Of 2,497 children evaluated at 1 of these sites for Lyme disease, 515 (20.6%) were infected.
Lise E. Nigrovic, Desire N. Neville, Fran Balamuth, Michael N. Levas, Jonathan E. Bennett, Anupam B. Kharbanda, Amy D. Thompson, John A. Branda, Aris C. Garro   +8 more
doaj   +1 more source

Arthritis Is Developed in Borrelia-Primed And -Infected Mice Deficient of Interleukin-17 [PDF]

, 2016
Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutralization of IL-17 with antibodies inhibits induction of arthritis in Borrelia-primed and -infected C57BL/6 wild-type mice ...
Kuo, Joseph, Munson, Erik, Nardelli, Dean T., Schell, Ronald F., Warner, Thomas F.   +4 more
core   +1 more source