Results 121 to 130 of about 700,016 (263)

Integrative molecular profiling identifies two molecularly and clinically distinct subtypes of blastic plasmacytoid dendritic cell neoplasm

Blood Cancer Journal, 2022
Axel Künstner, Julian Schwarting, Hanno M. Witte, Veronica Bernard, Stephanie Stölting, Kathrin Kusch, Kumar Nagarathinam, Nikolas von Bubnoff, Eva Maria Murga Penas, Hartmut Merz, Hauke Busch, Alfred C. Feller, Niklas Gebauer   +12 more
doaj   +1 more source

A study on predicting additional axillary lymph node positivity in breast cancer patients with positive sentinel lymph node to avoid axillary lymph node dissection. [PDF]

Gland Surg
Long X, Xin L, Chen Y, Huang H, Chen S.
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

The movement of lymph in the system of lymph node-lymph vessel and its regulation

Australasian Medical Journal, 2016
Myrzakhanov Nurken, Myrzakhanova Marzhan
openaire   +1 more source

Diagnostic Potential of Apparent Diffusion Coefficient-Based Lymph Node Classification in Breast Cancer Patients Undergoing [¹⁸F]FDG-PET/MRI. [PDF]

Diagnostics (Basel)
Peters HA, Scheuer M, Weiss D, Boschheidgen M, Ivan VL, Dietzel F, Mohrmann S, Ruckhäberle E, Herrmann K, Quick HH, Milosevic A, Minko P, Kirchner J, Umutlu L, Antoch G, Jannusch K.   +15 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Optimizing gastric cancer treatment: the role of LODDs in lymph node staging. [PDF]

Front Oncol
Hao Z, Niu H, Bi Y, Sun Q, Yang W.
europepmc   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

Lymph node fine-tuning FcγR signaling boosts anti-PD-1 therapy. [PDF]

J Immunother Cancer
Guérin MV, Ruggiu M, Feldmann LC, Corre B, Ombredanne P, Iannascoli B, Garcia Z, Lemaître F, Macdonald L, Guermonprez P, Grandjean CL, Bruhns P, Bousso P.   +12 more
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source