Results 271 to 280 of about 1,252,989 (357)

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Anatomical distribution of disease in pN1 prostate cancer with BCR post-RP: A PSMA-PET/CT-based analysis. [PDF]

BJUI Compass
Zuur LG, de Bie KCC, Wever L, Berrens AC, van Basten JA, van Melick HHE, Donswijk ML, Oprea-Lager DE, Vogel WV, van der Poel HG, Vis AN, van Leeuwen PJ.   +11 more
europepmc   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Gut microbiota and metabolite profiles in thyroid cancer lymph node metastasis: a multi-omics analysis. [PDF]

Sci Rep
Xu D, Chen J, Shi Y, Jiang X.
europepmc   +1 more source

Is there a benefit to sentinel lymph node biopsy in patients with T4 melanoma?

, 2009
Csaba Gajdos, Kent A. Griffith, Sandra L. Wong, Timothy M. Johnson, Alfred E. Chang, Vincent M. Cimmino, Lori Lowe, Carol R. Bradford, Riley S. Rees, Michael S. Sabel   +9 more
openalex   +2 more sources

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Minimally invasive esophagectomy drives a decade-long decline in upper mediastinal recurrence after esophageal cancer surgery: a real-world, single-center cohort study. [PDF]

Front Oncol
Zhang S, Hu A, Sun J, Wei Y, Zhang J, Zhong K, Cai H, Wang G.   +7 more
europepmc   +1 more source

Glycerinated Calf Lymph [PDF]

BMJ, 1902
openaire   +2 more sources

Nanoparticle Adjuvant Design Enhances Germinal Center Responses Targeting Conserved Subdominant Epitopes for Pan‐Coronavirus Vaccine Development

Advanced Science, EarlyView.
Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang, Kanella M. Cohen, Liqiang Chen, Xiaowo Kang, Chang Liu, Megan E. Demouth, Wenxia Jiang, Alexander R. Maldeney, Rong Tong, Zunlong Ke, Kartik Chandran, Wei Luo, Qian Yin   +12 more
wiley   +1 more source

Viral Distribution of Wild Boar Exposed to Low (Vaccine Candidate) and High Virulence African Swine Fever Virus Isolates: Immunohistochemical Characterization. [PDF]

Transbound Emerg Dis
Porras N, Rodríguez-Bertos A, Barroso-Arévalo S, Kosowska A, de Frutos MD, Pablo-Moreno JM, Sánchez-Segovia M, Barasona JÁ.   +7 more
europepmc   +1 more source