Results 271 to 280 of about 720,622 (316)

LIPUS Promotes Calcium Oscillation and Enhances Calcium Dependent Autophagy of Chondrocytes to Alleviate Osteoarthritis

Advanced Science, EarlyView.
A non‐invasive and safe physical therapy, low‐intensity pulsed ultrasound (LIPUS) can alleviate osteoarthritis. This study dynamically “visualizes” the invisible mechanical stimuli of LIPUS on living chondrocytes by fluorescence imaging technology in the form of calcium oscillations, confirming LIPUS maintains cartilage homeostasis by promoting ...
Mengtong Guan, Xiaoyu Han, Bo Liao, Wang Han, Lin Chen, Bin Zhang, Xiuqin Peng, Yu Tian, Gongyi Xiao, Xinhe Li, Liang Kuang, Ying Zhu, Dingqun Bai   +12 more
wiley   +1 more source

Recurrence pattern and mapping of lymph node metastases from rectal neuroendocrine tumors. [PDF]

Int J Colorectal Dis
Takaoka A, Tsukamoto S, Takamizawa Y, Moritani K, Imaizumi J, Kinugasa Y, Kanemitsu Y.   +6 more
europepmc   +1 more source

Tumor‐Adhesive Chitosan‐Derived Multi‐Immune Agonist Unleashes Strong and Durable Anti‐Cancer Immunity

Advanced Science, EarlyView.
A tumor‐adhesive chitosan‐derived immune agonist TACTIC is developed for strong and durable anti‐tumor immunity. The immune agonist exhibits multi‐targets and modulates both tumor cell immunogenicity and pro‐inflammatory responses in immune cells, thereby potentiating the therapeutic efficacy of clinical radiotherapy.
Huilan He, Liang Liu, Yun Zheng, Jinlong Ji, Li Cao, Chunlian Ye, Yu Sun, Ying Zhang, Zhiyuan Zhong   +8 more
wiley   +1 more source

Magnetic resonance imaging and ultrasound examination in preoperative pelvic staging of early-stage cervical cancer: post-hoc analysis of SENTIX study. [PDF]

Ultrasound Obstet Gynecol
Cibula D, Köhler C, Jarkovský J, Kocián R, Dundr P, Klát J, Zapardiel I, Landoni F, Frühauf F, Fischbach R, Borčinová M, Fischerová D.   +11 more
europepmc   +1 more source

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

Advanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan, Qing Pei, Haojie Sun, Haiyan Zhang, Zhigang Xie, Tao Zhang, Chong Ma   +6 more
wiley   +1 more source

Predictive risk-scoring model for lateral lymph node metastasis in papillary thyroid carcinoma. [PDF]

Sci Rep
Guo Y, Liu Y, Teng W, Pan Y, Zhang L, Feng D, Wu J, Ma W, Wang J, Xu J, Zheng C, Zhu X, Tan Z, Jiang L.   +13 more
europepmc   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

An ensemble learning model to predict lymph node metastasis in early gastric cancer. [PDF]

Sci Rep
Song K, Wu J, Xu M, Li M, Chen Y, Zhang Y, Chen H, Jiang C.   +7 more
europepmc   +1 more source

Reshape the Fates of Treg and CD8+T Cells Through IL‐2Rα by Synergizing Divergent Receptor‐Biased IL‐2 PEGylates

Advanced Science, EarlyView.
This study presents receptor‐biased IL‐2 PEGylates that selectively modulate IL‐2 receptor subunit interactions to enhance CD8⁺ T cell antitumor activity while curbing Treg activation and endothelial toxicity. The combined not‐α and not‐β variants balance immune stimulation and prevent T cell exhaustion, offering a novel, fine‐tuned approach for ...
Jiaqi Sun, Lingfeng Guo, Dezhong Ji, Mengfan Yu, Boyang Cheng, Xingxing Zhu, Yeshuang Yuan, Siyu Wu, Yuanjie Zhang, Wen Shi, Zhiqian Chen, Xindang Chu, Jiayu Hu, Liwen Hua, Yiming Wang, Yanning Zhu, Yu Mu, Hanwen Sun, Chuanling Zhang, Qi Wang, Sulong Xiao, Lihe Zhang, Bo Zhang, Demin Zhou   +23 more
wiley   +1 more source

Novel Preprocessing-Based Sequence for Comparative MR Cervical Lymph Node Segmentation. [PDF]

J Clin Med
Tarakçı EA, Çeliker M, Birinci M, Yemiş T, Gül O, Oğuz EF, Solak M, Kaba E, Çeliker FB, Özergin Coşkun Z, Alkan A, Erdivanlı ÖÇ.   +11 more
europepmc   +1 more source