Results 191 to 200 of about 709,300 (306)

Correlation of immune-inflammatory and tumor markers with lymph node metastasis in gastric cancer. [PDF]

Am J Transl Res
Wang YX, Zhou Y, Wang LG, Hou KZ.
europepmc   +1 more source

Lymph nodes

, 2020
Daniel Bell, Vikas Shah, Joshua Yap
openaire   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Predictors of sentinel lymph node mapping failure in endometrial cancer: a retrospective multicenter study. [PDF]

Front Oncol
Rokos T, Grendar M, Gobel J, Kotulova L, Kudela E, Pribulova T, Kozubik E, Kalman M, Biringer K.   +8 more
europepmc   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Ganglioneuroma has a potential for lymph node metastasis, not impacting recurrence. [PDF]

Front Oncol
Ozcelik EE, Sahin AB, Karaman Y, Erkan Ozmarasali B, Yalcinkaya U, Cubukcu E, Deligonul A, Evrensel T.   +7 more
europepmc   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source

Is lymph node metastasis an advanced event of gastrointestinal stromal tumor? [PDF]

Oncologist
Jiang Q, Zhang P, Yang W, Gao X, Fu Y, Zhang J, Zhang B, Feng F, Zhai G, Fu Y, Wu X, Zhang X, Wu X, Gao Z, Liang H, Zhou Y, Liu H, Tao K.   +17 more
europepmc   +1 more source

Transdermal Delivery of an mRNA‐Liposome Vaccine via Dissolving Microneedle to Preserve Vaccine Activity and Enhance Immune Activation

Advanced Science, EarlyView.
An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam, JiWon Ahn, Jiwoo Shin, Nahong Lee, Youjin Lee, Sung min Cho, Paul Kim, Geonwoo Kang, Sang‐Jun Ha, Hyungil Jung   +9 more
wiley   +1 more source

Prognostic Value of Non-nodal Regional Metastases in Predicting Sentinel Lymph Node Status in Cutaneous Melanoma: Multicenter Analysis of the Sentinel Lymph Node Working Group Database. [PDF]

Ann Surg Oncol
Riaz N, Leong SP, Kashani-Sabet M, White RL, Vetto JT, Schneebaum S, O'Donoghue C, Howard JH, Avisar E, Namm JP, Kosiorek H, Pockaj B, Faries M, Karakousis G, Zager JS, Olofsson Bagge R.   +15 more
europepmc   +1 more source