TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu +7 more
wiley +1 more source
Time interval between Sentinel Lymph Node Biopsy and Excision of Primary Melanoma does not impact long term outcomes in a large UK cohort [PDF]
Georgios Kounidas +3 more
openalex +1 more source
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo +12 more
wiley +1 more source
Robotic Extended Right Hemicolectomy with Complete Mesocolic Excision and D3 Lymph Node Dissection
Irbaz Hameed +2 more
openalex +2 more sources
Primary ectopic breast cancer of the vulva, treated with local excision of the vulva and sentinel lymph node biopsy: a case report [PDF]
Takayuki Ishigaki +8 more
openalex +1 more source
Renal cell carcinoma recurrence in the mediastinum lymph node 19 years after nephrectomy: a case report [PDF]
A 62-year-old male, who had undergone right nephrectomy to treat renal cancer 19 years earlier, was recently referred to our hospital to receive a detailed examination and treatment of mediastinal lymph node swelling.
並木, 幹夫 +8 more
core
Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang +25 more
wiley +1 more source
Inter-surgeon Variability in Cystic Artery Lymph Node Excision during Laparoscopic Cholecystectomy. [PDF]
Wysocki AP, Murphy S, Baade I.
europepmc +1 more source
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu +23 more
wiley +1 more source
Safety and practicality of an excisional lymph node study driving HIV cure research in South Africa [PDF]
Trevor Khaba +7 more
openalex +1 more source

