Results 231 to 240 of about 88,079 (354)

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

The clinicopathological features, treatment patterns, and prognosis of trichilemmal carcinoma: a retrospective case-series study. [PDF]

Am J Cancer Res
Shi C, Liu B, Wei B, Zhang W, Liu H, Chen P.   +5 more
europepmc   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

The Effect of Neoadjuvant Treatment on the Number of Lymph Node Dissection and Prognosis in Locally Advanced Rectal Cancer and Other Factors Affecting Lymph Node Metastasis. [PDF]

Cureus
Ozluk KK, Karaman N.
europepmc   +1 more source

A Case Duodenal Neuroendocrine Tumor: A Primary Tumor Site Recognized 30 Months after the Excision of Isolated Lymph Node Metastasis

, 2017
Yukio Maezawa, Mihoko Yamauchi, Tsutomu Sato, Tsutomu Hayashi, Naoto Yamamoto, Takashi Ohshima, Norio Yukawa, Shoji Yamanaka, Takaki Yoshikawa, Yasushi Rino, Munetaka Masuda   +10 more
openalex   +2 more sources

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Cervical lymphadenopathies: A Retrospective Single-Center Analysis of Patients Undergoing Excisional Biopsy. [PDF]

Sisli Etfal Hastan Tip Bul
Celik S, Slipcevic B, Ceviken E, Kilic O, Kalcioglu MT.   +4 more
europepmc   +1 more source

Vascularized Lymph Node Transfer Surgery for Successful Resolution of Long-Standing Lower Limb Lymphedema With Charles Excision: A Case Report [PDF]

Pankhuri Garg, Firoz Borle
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Unicentric Castleman disease in intraparotid lymph node: a case report. [PDF]

Maxillofac Plast Reconstr Surg
Jeong YH, Kim JS, Lee H, Ahn KM.
europepmc   +1 more source