Results 231 to 240 of about 495,796 (366)

DON‐Loaded Nanodrug‐T Cell Conjugates With PD‐L1 Blockade for Solid Tumor Therapy

Advanced Science, EarlyView.
This study establishes DON‐loaded T cell‐nanodrug conjugates with PD‐L1 blockade, creating a synergistic system. As a glutamine antagonist, sustained DON release enhances T‐cell endurance and infiltration by promoting memory differentiation and upregulating adhesion and motility genes, while PD‐L1 blockade alleviates immunosuppression and directs T ...
Xin Yang, Xiaoshuang Niu, Ye Su, Xiaoyun Ye, Wanqiong Li, Wenxuan Zeng, Xin Zhao, Zhuoying He, Qingyu Dong, Xiuman Zhou, Xinghua Sui, Guanyu Chen, Yanfeng Gao, Juan Liu   +13 more
wiley   +1 more source

Giant malignant melanoma of the upper limb: a case report and review of the literature. [PDF]

J Med Case Rep
Villegas K, Bathobakae L, Fatima T, Wilkinson T, Ali I, Hafez N.   +5 more
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Benefit of laparoscopic two-team transanal beyond total mesorectal excision for advanced and recurrent rectal cancer with invasion: a retrospective study compared with conventional laparoscopic approach. [PDF]

Tech Coloproctol
Shioi I, Shiraishi T, Shimizu Y, Uehara K, Seki T, Hosoi N, Tateno K, Endo M, Uchida S, Yamaguchi A, Katayama C, Shibasaki Y, Komine C, Osone K, Okada T, Kimura A, Sano A, Sakai M, Shirabe K, Saeki H.   +19 more
europepmc   +1 more source

A case report: Anaesthetic management in a child with Rosai-Dorfman disease undergoing cervical lymph node excisional biopsy

R. Rakshitha, Raghavendra H Kalal
openalex   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

Correction: Tumoral Melanosis: A Case Series of a Rare Clinical Entity. [PDF]

Dermatol Ther (Heidelb)
Ariasi C, Artelli GL, Zane C, Perantoni M, Soglia S, La Rosa G, Maione V, Venturini M, Zambelli C, Licata G, Rossi M, Arisi M.   +11 more
europepmc   +1 more source

A novel technique for transdiaphragmatic latero-pericardial cardiophrenic lymph node excision using the minimally invasive surgical access procedure in patient with advanced stage ovarian cancer

Candost Hanedan, Hande Nur Öncü, Tuba Zengin, Vakkaş Korkmaz   +3 more
openalex   +1 more source

Blood Biomarker‐Based Predictive Indicator for Liver Metastasis in Alpha‐Fetoprotein‐Producing Gastric Cancer and Multi‐Omics Tumor Microenvironment Insights

Advanced Science, EarlyView.
Alpha‐fetoprotein‐producing gastric cancer (AFPGC), a rare and aggressive subtype of gastric cancer, presents a high risk of liver metastasis. This study introduces the ANLiM score, a blood biomarker‐based predictive indicator for assessing liver metastasis and immunotherapy response.
Yongfeng Ding, Yiran Chen, Jing Zhang, Qingrui Wang, Songting Zhu, Junjie Jiang, Chao He, Jincheng Wang, Laizhen Tou, Jingwei Zheng, Bicheng Chen, Sizhe Hu, Xiongfei Yu, Haohao Wang, Yimin Lu, Mei Kong, Yanyan Chen, Haiyong Wang, Haibin Zhang, Hongxia Xu, Fei Teng, Xian Shen, Nong Xu, Jian Ruan, Zhan Zhou, Jun Lu, Lisong Teng   +26 more
wiley   +1 more source

Advancement of indocyanine green fluorescence imaging technology in laparoscopic surgery for rectal cancer. [PDF]

World J Gastrointest Surg
Wu CY, Zhu YJ, Ye K.
europepmc   +1 more source