Results 161 to 170 of about 276,653 (321)

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

Advanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu, Meicen Wu, Qingyang Lyu, Chang Yang, Ni Fan, Kang Chen, Weiping Wang   +6 more
wiley   +1 more source

EXPERIMENTAL STUDIES ON LYMPH NODE METASTASIS IN RABBITS INPLANTED WITH BROWN-PEARCE CANCER

, 1963
Ikuichiro Hiroto, TATSUMI IZAWA
openalex   +2 more sources

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

Pattern of lymph node metastasis in supraglottic carcinoma

, 1970
MA Quayum, AHMZ Huq, Tarafder Kh
openalex   +2 more sources

Nuclear‐Localized BCKDK Facilitates Homologous Recombination Repair to Support Breast Cancer Progression and Therapy Resistance

Advanced Science, EarlyView.
Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu, Jiaqian Feng, Tingting Pan, Pinggen Zhang, Ling Ye, Zetan Jiang, Zilong Zhou, Qiankun Mao, Jian Li, Xinyi Yang, Ping Gao, De Huang, Huafeng Zhang   +12 more
wiley   +1 more source

CT Synthesis with Conditional Diffusion Models for Abdominal Lymph Node Segmentation [PDF]

arXiv
Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and indistinguishable lesions, and limited annotated data.
arxiv  

c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma

, 1989
Manoochehr Tavassoli, Philip Quirke, Farzin Farzaneh, NJ Lock, LV Mayne, N Kirkham   +5 more
openalex   +1 more source

A Case of Merkel Cell Carcinoma with Parotid Lymph Node Metastasis [PDF]

, 1994
Çağlar Batman, Aydın Sav, Bülent Mamıkoğlu, Cüneyd Üneri   +3 more
openalex   +1 more source

Plac1+ Tumor Cell‐Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer

Advanced Science, EarlyView.
Meng et al. screen genes in the CTAs family and find Plac1 is specifically expressed in head and neck squamous cell carcinoma (HNSCC) cells. They reveal that Plac1 expression promotes HNSCC progression directly by activating PI3K/AKT signaling pathway.
Xiaoyan Meng, Zhonglong Liu, Lu Zhao, Ran Li, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He   +8 more
wiley   +1 more source

Camouflaged Nanozymes with Oxidation‐Promoting Activities Triggering Ferroptosis for Radio‐Immunotherapy

Advanced Science, EarlyView.
This study develops a cancer cell membrane‐coated nanozyme that enhances radiotherapy and reshapes the immunosuppressive microenvironment by generating oxygen in situ and disrupting tumor antioxidant defenses, offering a new strategy for breast cancer radioimmunotherapy.
Kun Qiao, Yongbiao Huang, Shipeng Ning, Meng Lyu, Jieqiong Xie, Shiyuan Zhang, Xiuxin Lu, Yuan Yu, Wei Jiang, Bo Liu, Kelong Fan, Tong Liu   +11 more
wiley   +1 more source