Results 231 to 240 of about 2,036,397 (332)

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, EarlyView.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

Harnessing the power of tumor-draining lymph nodes: unveiling predictive biomarkers for immune checkpoint inhibitor. [PDF]

Explor Target Antitumor Ther
Chen Z, Yu J, Guo Z, Chen S, Li Y, Zhou Q, Wang L.   +6 more
europepmc   +1 more source

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

Advanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu, Meicen Wu, Qingyang Lyu, Chang Yang, Ni Fan, Kang Chen, Weiping Wang   +6 more
wiley   +1 more source

Unleashing the therapeutic potential of tumor-draining lymph nodes: spotlight on bladder cancer. [PDF]

J Transl Med
Yang X, Wu X, Hao X, Li T, Guo H, Yang R.   +5 more
europepmc   +1 more source

Purification of the Alkaline Phosphatase of the Bovine Lymph-node

, 1951
Masanori Takahashi, Yasushi Hayashi
openalex   +2 more sources

Antibody Formation by Rabbit Lymph Node Cells [PDF]

, 1964
Giuseppe Attardi, Melvin Cohn, Kengo Horibata, Edwin S. Lennox   +3 more
openalex   +1 more source

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with 89Zr/131I‐Labeled Tinurilimab

Advanced Science, EarlyView.
This study investigates the integrated diagnostic and therapeutic strategy utilizing 89Zr/131I‐labeled tinurilimab for the management of malignant lung nodules, with a particular focus on lung adenocarcinoma (LUAD). CEACAM6, which is highly expressed in most LUAD patients, activates the Src/FAK signaling pathway, thereby promoting cell proliferation ...
Chongyang Chen, Keying Zhu, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Min Yang   +8 more
wiley   +1 more source

Divergent gene signatures and neutrophil enrichment in lymph nodes of inflammatory arthritis patients. [PDF]

Arthritis Res Ther
O'Byrne AM, Bolt JW, van Ansenwoude CMJ, van der Heijde M, Semmelink JF, Jongejan A, Moerland PD, Maas M, van de Sande MGH, van Baarsen LGM.   +9 more
europepmc   +1 more source

THE SYNTHESIS AND SECRETION OF γ-GLOBULINS BY LYMPH NODE CELLS, I. THE MICROSOMAL COMPARTMENTALIZATION OF γ-GLOBULINS [PDF]

, 1967
Robert M. Swenson, Milton Kern
openalex   +1 more source

SSRP1/SLC3A2 Axis in Arginine Transport: A New Target for Overcoming Immune Evasion and Tumor Progression in Peripheral T‐Cell Lymphoma

Advanced Science, EarlyView.
Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren, Lei Fan, Ling Wang, Yanping Liu, Jie Zhang, Boya Wang, Ruize Chen, Xiao Chen, Lingyu Zhuang, Yaping Zhang, Handong Sun, Jianyong Li, Wenyu Shi, Hui Jin   +13 more
wiley   +1 more source