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Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li   +13 more
wiley   +1 more source

Phenotypic alterations in the immune system and tolerance induction in tumor-draining lymph nodes. [PDF]

open access: yesIran J Basic Med Sci
Koohini Z   +3 more
europepmc   +1 more source

Structural and vascular alterations of deep cervical lymph nodes in amyloid PET-positive Alzheimer's disease patients. [PDF]

open access: yesCereb Circ Cogn Behav
Kim TH   +7 more
europepmc   +1 more source

Recurrent laryngeal nerve lymph nodes status prediction after neoadjuvant therapy for thoracic esophageal squamous cell carcinoma. [PDF]

open access: yesInsights Imaging
Wu F   +11 more
europepmc   +1 more source
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When is a Lymph Node Dissection a Lymph Node Dissection? The Number of Lymph Nodes Resected in Sentinel and Axillary Lymph Node Dissections

Annals of Surgical Oncology, 2012
We sought to compare the number of lymph nodes (LN) resected in axillary lymph node dissections (ALND) and sentinel lymph node dissections (SLND), and to assess the validity of registry reporting for axillary staging in breast cancer.Women in the California Cancer Registry who underwent surgical axillary staging for T1/T2, M0 breast cancer between 2004
Windy, Olaya   +5 more
openaire   +2 more sources

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