Results 271 to 280 of about 753,517 (348)

Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity

Advanced Science, EarlyView.
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang, Wen‐Chi Xue, Chao Liang, Pan Liu, Yao Lei, Jiaqi He, Ran Cheng, Weidong Nie, Jianxiong Wang, Jie Tang, Hai‐Yan Xie   +10 more
wiley   +1 more source

Metastatic Papillary Thyroid Carcinoma in the Lymph Nodes Without Identifiable Primary Tumor in the Thyroid. [PDF]

Cureus
Carrillo A, Arbab F, Ramani NS.
europepmc   +1 more source

Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice

Advanced Science, EarlyView.
This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng, Bing Jiang, Wei Lu, Przemyslaw Zalewski, Jun He, Xiaoyang Li, Yiping Cao, Yiguo Zhao, Cuixia Sun, Katsuyoshi Nishinari, Yapeng Fang   +10 more
wiley   +1 more source

The Interplay between the Gut and Ketogenic Diets in Health and Disease

Advanced Science, EarlyView.
This review synthesizes current knowledge on the interaction between ketogenic diets and the gut, covering gut physiology, intestinal immunity, and the gut microbiome. It explores innovative methods for tailoring the diet to maximize benefits while reducing side effects. Emphasis is placed on gut‐mediated mechanisms as a critical interface between diet
Chunlong Mu, Jong M. Rho, Jane Shearer
wiley   +1 more source

A radiomics-based model for predicting lymph nodes metastasis of pancreatic ductal adenocarcinoma: a multicenter study. [PDF]

Insights Imaging
Zhu L, Zhao B, Xia T, Chang D, Xia C, Liu M, Li R, Cao B, Qiu Y, Yu Y, Zhou S, Chen H, Cai W, Ding Z, Lu C, Tang T, Song Y, Wang Y, Ye J, Liu Y, Ju S.   +20 more
europepmc   +1 more source

Unveiling Macrophage Content as a Predictive Biomarker for Intraoperative ICG Imaging Efficacy in Lung Cancer

Advanced Science, EarlyView.
Indocyanine Green (ICG)‐guided lung cancer surgery efficacy varies significantly among patients. This study identifies tumor macrophage content as a predictive biomarker. Macrophages are primary ICG reservoirs, storing seven‐fold more ICG than cancer cells.
Yue Yan, Jiahui Mi, Yun Li, Guanchao Jiang, Yimeng Zhang, Yanguo Liu, Hui Zhao, Jianfeng Li, Xing Yang, Jun Wang, Fan Yang, Kezhong Chen, Yiguang Wang, Jian Zhou   +13 more
wiley   +1 more source

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

Advanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang, Yongjian Zhang, Yajuan Fu, Dangjin Ke, Qi Chen, Sijie Shao, Panpan Xue, Yuanchun Chen, Xuemei Zeng, Shuangqian Yan   +9 more
wiley   +1 more source

A subgroup analysis of locally advanced nasopharyngeal carcinoma patients with small lymph nodes and large nodes using adaptive radiotherapy. [PDF]

BMC Cancer
Yao W, Dong S, Xu P, Zhong Z, Li Z, Zhou Y, Fang Y, Lin Z, He M, Hu J, Xia W, Xu S.   +11 more
europepmc   +1 more source