Results 91 to 100 of about 13,250 (289)

Resveratrol: Molecular Mechanisms, Health Benefits, and Potential Adverse Effects

MedComm, Volume 6, Issue 6, June 2025.
As a polyphenol substance with important potential, resveratrol has important potential in degenerative diseases, cardiovascular diseases, cancer, neurological diseases, etc. However, it is still necessary to pay attention to its bioavailability and potential adverse effects.
Zhuo‐qun Ren, Sheng‐yuan Zheng, Zhengcheng Sun, Yan Luo, Yu‐tong Wang, Ping Yi, Yu‐sheng Li, Cheng Huang, Wen‐feng Xiao   +8 more
wiley   +1 more source

Pneumothorax as a Presentation of Tuberous Sclerosis-Associated Lymphangioleiomyomatosis

European Journal of Case Reports in Internal Medicine, 2019
Tuberous sclerosis complex (TSC) is a rare, autosomal dominant disorder with a recognized phenotypic variability with clinical manifestations developing continuously throughout life. The follow-up of TSC patients is challenging.
Duarte Lages Silva, Pedro Pinto, Miguel Costa, Rosana Maia, Carmelia Rodrigues   +4 more
doaj   +1 more source

Sirolimus Decreases Circulating Lymphangioleiomyomatosis Cells in Patients With Lymphangioleiomyomatosis [PDF]

Chest, 2014
Lymphangioleiomyomatosis (LAM), sporadic or in women with tuberous sclerosis complex (TSC), is characterized by cystic lung destruction, lymphatic involvement (eg, chylous pleural effusions, lymphangioleiomyomas), and renal angiomyolipomas (AMLs). The multisystem manifestations of LAM appear to result from metastatic dissemination of LAM cells bearing ...
Hai-Ping Wu, Xiong Cai, J. Philip McCoy, Mary Haughey, Leigh Samsel, Mario Stylianou, Joel Moss, Suowen Xu, Thomas N. Darling, Gustavo Pacheco-Rodriguez   +9 more
openaire   +3 more sources

Initial presentation of lymphangioleiomyomatosis in third trimester of pregnancy

BMJ Case Reports, 2021
Lymphangioleiomyomatosis (LAM) is a progressive cystic lung disease which mostly affects premenopausal women and could be exacerbated by pregnancy. Therefore, it is thought that oestrogen plays an important role in LAM pathogenesis.
Lily Alkemade, Meike A T Berghuis, B. Koopman, M. V. van Pampus   +3 more
semanticscholar   +1 more source

Mortality in Tuberous Sclerosis Complex in the United Kingdom, 2016–2022

Journal of Intellectual Disability Research, Volume 69, Issue 6, Page 457-464, June 2025.
ABSTRACT Background Tuberous sclerosis complex (TSC) is a genetic condition caused by mutations in either TSC1 or TSC2 genes, affecting around two million people globally. This study aims to examine causes of death in TSC and explore factors contributing to mortality in people with TSC in the United Kingdom in recent years following updated management ...
Callum Richard Thomas Kidson, Ne‐Ron Loh, Yasir Ahmed Syed   +2 more
wiley   +1 more source

Pulmonary lymphangioleiomyomatosis with parietal pleural involvement: A case report and discussion of pathogenesis using pulmonary lymphangitic carcinomatosis as a model

Human Pathology: Case Reports, 2019
We report a case of sporadic pulmonary lymphangioleiomyomatosis presenting with chylothorax and with parietal pleural involvement by the disease. The implications for the anatomic distribution of lesions in pulmonary lymphangioleiomyomatosis is discussed.
Shunei Asao, B.A., Charles M. Lombard, M.D., Pei Tsau, M.D.   +2 more
doaj  

Leiomyomatosis-like lymphangioleiomyomatosis

Medicine, 2021
Introduction: Tuberous sclerosis complex is an inherited multisystemic disorder with manifestations in various organ systems as a result of a mutation of 1 of 2 tumor suppressor genes, tuberous sclerosis complex-1 or tuberous sclerosis complex-2 ...
Ergin Erginoz, H. Taşkın, Gokce Hande Cavus, A. Zengin   +3 more
semanticscholar   +1 more source

RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

Advanced Science, Volume 12, Issue 19, May 22, 2025.
RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao, Jiali Jin, Runzhi Huang, Siqiao Wang, Sihui Song, Yu Zhang, Yongai Li, Jun Lin, Zhengyan Chang, Zongqiang Huang, Wei Sun, Huabin Yin, Dianwen Song, Jianru Xiao, Ping Wang, Tong Meng   +15 more
wiley   +1 more source

A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult

Journal of the ASEAN Federation of Endocrine Societies
A 23-year-old female smoker presented in late 2008 with a large left pneumothorax. She had multiple spontaneous pneumothoraces in 2007 which required pleurectomy.
Chng Chiaw Ling
doaj   +1 more source

Pulmonary tuberous sclerosis [PDF]

, 2009
Pulmonary involvement in tuberous sclerosis is very rare and seems to be associated with a more benign course. We present a 21-year-old woman with bilateral angiomyolipoma.
Razi, E.
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