Results 51 to 60 of about 4,369 (185)

Case report - An acute presentation of lymphangiomatosis.

, 2012
IntroductionLymphangioma is an uncommon malformation of lymphatic system. Multiple colonic lymphangioma named as lymphangiomatosis is considered an extremely rare disease.Presentation of caseWe report a case of colonic lymphangiomatosis presenting as ...
Nason, G J, Barry, B D, Shatwan, R, Neary, P   +3 more
core   +1 more source

Video_1_Laparoscopy for evaluating mesenteric lymphangiomatosis: A case report.mov

, 2022
BackgroundLymphangiomatosis is an extremely rare disease with potential soft tissue, bone, and spleen involvement, which can be characterized by lymphangioma. Only a few cases of colon and mesenteric lymphangiomatosis have been reported. We report a case
Xishan Wang (282956), Yefeng Yin (13985289), Rongdi Wang (13985292)   +2 more
core   +1 more source

Expansion of the Phenotype of Lymphatic Anomalies Caused by Somatic Activating BRAF Variant. [PDF]

Pediatr Blood Cancer
ABSTRACT Background The somatic activating variant in BRAF (p.V600E) was recently described as a novel cause of macrocystic head and neck lymphatic malformations in three individuals. Other recent studies profiling the genetic causes of more complex lymphatic anomalies identified this same pathogenic BRAF variant.
Fox MD, Kumar S, Britt AD, Srinivasan AS, Surrey LF, Vatsky SE, Borst AJ, Hakonarson H, Li D, Sheppard SE, Snyder KM, Adams DM.   +11 more
europepmc   +2 more sources

A rare case of retroperitoneal and mesenteric lymphangiomatosis

Radiology Case Reports, 2020
Lymphagiomatosis are rare benign malformations of the lymphatic system. They are more commonly seen during childhood and are frequently asymptomatic and incidentally found in the adult patient.
Wen Yang Shaun Chan, MBBS (Singapore), MRCS (Edin), MMed (Surg), Kenneth Eng Ling Kwan, MBBS (Singapore), MMed, FRCR, Li Tserng Teo, MBBS (Singapore), MMed (Surg), FRCS (Edin)   +2 more
doaj   +1 more source

Congenital lymphangiomatosis: Multidisciplinary approach

Journal of Pediatric Surgery Case Reports, 2020
Background: Diffuse lymphangiomatosis is a rare disorder of the lymphatic vessels. Its prognosis is poor and its treatment not codified. Methods: We describe the case of a 14 years old boy known for a lymphatic malformation of the left chest wall with ...
Oumama El Ezzi, Guillaume Saliou, Carole Gengler, Anthony de Buys Roessingh   +3 more
doaj   +1 more source

RAS Inhibitor RMC‐7977 Blocks Vascular Overgrowth of NRASQ61R Mutant Endothelial Cells

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT RAS mutations occur in patients with several types of vascular anomalies, but effective treatments remain limited. To address this need, we evaluated the RAS (ON) multi‐selective inhibitor RMC‐7977 in human endothelial cells (ECs) expressing the NRASQ61R mutation found in kaposiform lymphangiomatosis (KLA).
Sara Alharbi, Svatava Merkle, Patricia Pastura, C. Griffin McDaniel, George S. Zaky, Andrew M. Waters, Timothy D. Le Cras   +6 more
wiley   +1 more source

Unusual clinical manifestation of lymphangiomatosis [PDF]

, 2011
A 6-year- old boy presented with disseminated intravascular coagulation and was diagnosed with lymphangiomatosis. Disseminated intravascular coagulation develops in a minority of cases. Bone lesions were present on his left shoulder.
C Heijmans, O Prieur, N Damry, C Christophe   +3 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Systemic generalised lymphangiomatosis: unknown aetiology and a challenge to treat

, 2021
We describe a case of a woman diagnosed at the age of 35 years with a generalised mediastinal and abdominal lymphangiomatosis associated with a protein losing enteropathy, who successfully improved when treatment with sirolimus was initiated.SCOPUS: ar ...
Velkeniers, Brigitte, Van Meerhaeghe, Tess, Vandenbroucke, Frederik, Tess Van Meerhaeghe, Brigitte Velkeniers, Frederik Vandenbroucke   +5 more
core   +1 more source