Results 181 to 190 of about 419,246 (294)

Endothelial Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 Is Critical for Lymphatic Vascular Development and Function [PDF]

, 2016
Rachel J. Roth Flach, Changan Guo, Laura V. Danai, Joseph C. Yawe, Sharvari Gujja, Yvonne J. K. Edwards, Michael Czech   +6 more
openalex   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

Advanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang, Chong Han, Yangli Xie, Shoutao Qiu, Shaoyang Zhang, Jingjia He, Zejian Wang, Zhenlin Zhang, Huijuan Liu, Lin Chen, Baojie Li   +10 more
wiley   +1 more source

The role of cardiac lymphatic dysfunction in the progression of myocarditis. [PDF]

Front Cardiovasc Med
Kurup S, Hu DA, Kume T.
europepmc   +1 more source

S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer

, 2019
Hiromichi Nakayama, Kenoki Ohuchida, Akiko Yonenaga, Akiko Sagara, Yohei Ando, Shin Kibe, Shin Takesue, Toshiya Abe, Sho Endo, Kazuhiro Koikawa, Takashi Okumura, Koji Shido, Kei Miyoshi, Kohei Nakata, Taiki Moriyama, Yoshihiro Miyasaka, Shigetaka Inoue, Takao Ohtsuka, Kazuhiro Mizumoto, Masafumi Nakamura   +19 more
openalex   +2 more sources

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source

Bilateral inguinal vesicles clustered on an ecchymotic background

JAAD Case Reports
Frank Z. Jing, MD, Michael Camilleri, MD, Julio C. Sartori-Valinotti, MD   +2 more
doaj   +1 more source

A Lymphatic Perspective on Obesity and Inflammatory Arthritis: New Disease-Modifying Potential in Rheumatology. [PDF]

J Clin Med
den Braanker H, van der Valk ES, Bisoendial RJ.   +2 more
europepmc   +1 more source

Recurrent advanced lower extremity lymphedema following initial successful vascularized lymph node transfer: a clinical and histopathological analysis [PDF]

, 2017
Chang, Wei-ling, Chen, Hung-chi, Chen, Tsung-wei, Ciudad, Pedro, Date, Shivprasad, Huang, Tsung-chun, Manrique, Oscar J., Maruccia, Michele, Nicoli, Fabio   +8 more
core   +2 more sources

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Comparing the direct effect of lymphatic dynamic transport after lower-level laser therapy in healthy volunteers: a randomized controlled trial. [PDF]

Lasers Med Sci
Bae H, Jeon JY, Choi SH, Rhee MH, Kim YJ, Kong IJ, Eom JR, Yoon JA.   +7 more
europepmc   +1 more source