Results 31 to 40 of about 37,654 (251)

Effects of MEK-inhibitor treatment in infants with lymphatic abnormalities in noonan syndrome

Frontiers in Pediatrics
Noonan syndrome (NS) is a genetic disorder associated with dysregulation of the RAS/MAPK signaling pathway and is frequently accompanied by lymphatic abnormalities.
J. Wagenpfeil, J. Wagenpfeil, K. Hoß, A. Henkel, D. L. Kütting, J. A. Luetkens, A. Mueller, A. Mueller, C. C. Pieper, C. C. Pieper, A. Groteklaes, A. Groteklaes   +11 more
doaj   +1 more source

Una variación anatómica: la desembocadura aberrante del conducto torácico

Biomédica: revista del Instituto Nacional de Salud, 2009
En uno de los cadáveres disecados durante el primer semestre de 2006 en el anfiteatro del Departamento de Morfología de la Universidad del Valle en Cali (Colombia), se encontró una variación anatómica poco descrita en la literatura científica mundial. Se
Elizabeth Peña, Janneth Zuñiga
doaj   +1 more source

Hydrops fetalis due to abnormal lymphatics. [PDF]

Archives of Disease in Childhood, 1987
A case of generalised lymphatic abnormality that presented with hydrops fetalis is described. This seems to be the first such case reported.
K P, Windebank, N A, Bridges, I, Ostman-Smith, J E, Stevens   +3 more
openaire   +2 more sources

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

MR‐lymphangiography identifies lymphatic pathologies in patients with idiopathic recurrent cervical swelling

Laryngoscope Investigative Otolaryngology, 2022
Background Idiopathic recurrent cervical swelling may be caused by lymphatic abnormalities. Methods Ten patients (9 females, mean age 51.2 ± 7) with idiopathic recurrent cervical swelling underwent MR‐lymphangiography (MRL).
Marius Vach, Julia Wagenpfeil, Andreas Henkel, Sebastian Strieth, Julian Alexander Luetkens, Yon‐Dschun Ko, Hans Heinz Schild, Ulrike Irmgard Attenberger, Claus Christian Pieper   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The role of magnetic resonance imaging in the prenatal management of a lymphatic malformation

Journal of the Belgian Society of Radiology, 2014
We report the magnetic resonance imaging (MRI) findings in a case of extensive fetal lymphatic malformation involving the upper left arm and axillo-thoraco-abdominal wall found on routine prenatal ultrasound (US) examination at 22 weeks of gestation. MRI
YP Liu, WK Su, YL Lin, YK Fan
doaj   +1 more source

NON-CONTRAST MR LYMPHOGRAPHY OF RARE LYMPHATIC ABNORMALITIES

Lymphology, 2021
Detailed imaging of the lymphatic system often requires direct injection of contrast into lymph nodes which can be technically challenging, time consuming, and produce painful stimuli. We sought to describe the use of non-contrast MR lymphography (NCMRL) for normal controls and patients with a variety of rare disorders associated with lymphatic ...
M D, Seckeler, L, Moedano, D, Mustacich, B T, Kalb, M, Saranathan, J-P, Galons, M H, Witte   +6 more
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source