Abnormal lymphatic S1P signaling aggravates lymphatic dysfunction and tissue inflammation
, 2023 BACKGROUNDLymphedema is a global health problem with no effective drug treatment. Enhanced T cell immunity and abnormal lymphatic endothelial cell (LEC) signaling are promising therapeutic targets for this condition. Sphingosine-1-phosphate (S1P) mediates a key signaling pathway required for normal LEC function, and altered S1P signaling in LECs could ...
Dongeon Kim +17 more
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Utilizing lymphatic cell markers to visualize human lymphatic abnormalities [PDF]
Journal of Biophotonics, 2017 In vivo visualization of the human lymphatic system is limited by the mode of delivery of tracing agents, depth of field and size of the area examined, and specificity of the cell markers used to distinguish lymphatic endothelium from the blood vessels and the surrounding tissues.
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Clinical evaluation of endolymphatic radiotherapy in malignant lymphoma [PDF]
, 1974 By endolymphatic injection of radioisotope 131I.Lipiodol, so.called endolymphatic radiotherapy, we treated 10 cases with malignant lymphoma and found a marked tumor reduction to normal size in all the 10 cases we tried.
Irino, Shozo +3 more
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Prenatal Ultrasound Diagnosis of Klippel–Trenaunay Syndrome
Diagnostics, 2023 Klippel–Trenaunay syndrome (KTS) is a very rare vascular malformation syndrome also referred to as a capillary–lymphatic–venous malformation with unknown aetiology.
Nicolae Gică +6 more
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Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]
, 2009 INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat +2 more
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Case report: Noonan syndrome with protein-losing enteropathy
Frontiers in Genetics, 2023 Background: Noonan syndrome (NS) is characterized by typical facial features, short stature, congenital heart defects and other comorbidities. Lymphedema and chylous pleural effusions are also common in NS, but protein-losing enteropathy (PLE) is rarely ...
Yang Ou +6 more
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Peripheral vascular malformations : modern imaging [PDF]
, 2018 Currently the major aim in peripheral vascular malformation diagnosis, crucial for subsequent management and treatment, is to identify its haemodynamic characteristics.
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Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]
, 2020 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
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Non-immune fetal hydrops: etiology and outcome according to gestational age at diagnosis. [PDF]
, 2020 OBJECTIVE: Fetal hydrops is associated with increased perinatal morbidity and mortality. The etiology and outcome of fetal hydrops may differ according to the gestational age at diagnosis.
A. Bhide +12 more
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Hydrops fetalis due to abnormal lymphatics. [PDF]
Archives of Disease in Childhood, 1987 A case of generalised lymphatic abnormality that presented with hydrops fetalis is described. This seems to be the first such case reported.
K P, Windebank +3 more
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