Results 1 to 10 of about 187,834 (350)
Immunopathogenesis of lymphatic filarial disease [PDF]
Seminars in Immunopathology, 2012 Although two thirds of the 120 million people infected with lymph-dwelling filarial parasites have subclinical infections, ~40 million have lymphedema and/or other pathologic manifestations including hydroceles (and other forms of urogenital disease), episodic adenolymphangitis, tropical pulmonary eosinophilia, lymphedema, and (in its most severe form)
Subash Babu, Thomas B. Nutman
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Gastrointestinal lymphatics in health and disease [PDF]
Pathophysiology, 2009 Lymphatics perform essential transport and immune regulatory functions to maintain homeostasis in the gastrointestinal (GI) system. Although blood and lymphatic vessels function as parallel and integrated systems, our understanding of lymphatic structure, regulation and functioning lags far behind that of the blood vascular system. This chapter reviews
J. Steven Alexander +3 more
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Lymphatic endothelium in health and disease [PDF]
Cell and Tissue Research, 2018 The lymphatic vascular system has an important role in the maintenance of tissue fluid pressure homeostasis, in the mediation of the afferent immune response via recruitment of antigen-presenting cells toward draining lymph nodes, and in the intestinal ...
Detmar, Michael, Jurisic, Giorgia
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Lymphatic Connexins and Pannexins in Health and Disease [PDF]
International Journal of Molecular Sciences, 2021 This review highlights current knowledge on the expression and function of connexins and pannexins, transmembrane channel proteins that play an important role in intercellular communication, in both the developing and mature lymphatic vasculature. A particular focus is given to the involvement of these proteins in functions of the healthy lymphatic ...
Avigail Ehrlich +3 more
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Lymphatic Function in Autoimmune Diseases [PDF]
Frontiers in Immunology, 2019 Lymphatic vessels are critical for clearing fluid and inflammatory cells from inflamed tissues and also have roles in immune tolerance. Given the functional association of the lymphatics with the immune system, lymphatic dysfunction may contribute to the
Noa Schwartz +10 more
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The lymphatics in kidney health and disease [PDF]
Nature Reviews Nephrology, 2021 The mammalian vascular system consists of two networks: the blood vascular system and the lymphatic vascular system. Throughout the body, the lymphatic system contributes to homeostatic mechanisms by draining extravasated interstitial fluid and facilitating the trafficking and activation of immune cells. In the kidney, lymphatic vessels exist mainly in
Michael D. Donnan +2 more
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Targeting lymphatics in inflammatory bowel disease
Oncotarget, 2015 The inflammatory bowel diseases (IBDs), consisting of ulcerative colitis (UC) and Crohn's disease (CD), are characterized by chronic inflammation of the gastrointestinal tract in genetically susceptible individuals exposed to environmental risk factors.
Silvia D’Alessio +2 more
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A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis. [PDF]
, 2013 BACKGROUND: The success of programs to eliminate lymphatic filariasis (LF) depends in large part on their ability to achieve and sustain high levels of compliance with mass drug administration (MDA). This paper reports results from a comprehensive review
Fischer, Peter U +2 more
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Therapeutic approaches to CNS diseases via the meningeal lymphatic and glymphatic system: prospects and challenges [PDF]
Frontiers in Cell and Developmental BiologyThe brain has traditionally been considered an “immune-privileged” organ lacking a lymphatic system. However, recent studies have challenged this view by identifying the presence of the glymphatic system and meningeal lymphatic vessels (MLVs).
Rui Zhang +3 more
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Lymphatic‐specific methyltransferase‐like 3‐mediated m6A modification drives vascular patterning through prostaglandin metabolism reprogramming [PDF]
MedCommLymphangiogenesis plays a pivotal role in the pathogenesis of various vascular disorders, including ocular vascular diseases and cancers. Deregulation of N6‐methyladenosine (m6A) modification has been identified as a key contributor to human diseases ...
Lianjun Shi +7 more
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