Results 1 to 10 of about 24,249 (204)
Effects of adenosine on lymphangiogenesis. [PDF]
PLoS ONE, 2014 BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood but promotes tumor spread and metastasis during ...
Bénédicte Lenoir +6 more
doaj +7 more sources
Lymphatics and Lymphangiogenesis in the Eye [PDF]
Journal of Ophthalmology, 2012 Lymphatic is a prerequisite for the maintenance of tissue fluid balance and immunity in the body. A body of evidence also shows that lymphangiogenesis plays important roles in the pathogenesis of diseases such as tumor metastasis and inflammation.
Shintaro Nakao +2 more
doaj +7 more sources
Lymphatic Endothelial Cells and Organ-Associated Lymphangiogenesis in Tumor Microenvironment [PDF]
CellsLymphatic vessels are a kind of heterogeneous and versatile component of the lymphatic system, with a unique ability to respond to environmental changes in different organs.
Rui-Cheng Ji
doaj +3 more sources
Lymphangiogenesis and cancer metastasis [PDF]
Journal of Cellular and Molecular Medicine, 2009 Abstract Anatomy and function of the lymphatic system Tumour‐induced lymphangiogenesis promotes metastasis Tumour‐induced lymph node lymphangiogenesis precedes cancer metastasis to lymph nodes Tumour cell invasion into lymphatic vessels Peri‐ and intra‐tumoral lymphangiogenesis Lymphatic vessel markers and lymphangiogenic growth factors Preventive and ...
Mumprecht V, Detmar M
exaly +4 more sources
Signal Transduction and Targeted TherapyEphrinB2 (erythropoietin-producing hepatoma interactor B2) is a key Eph/ephrin family member, promoting angiogenesis, vasculogenesis, and lymphangiogenesis during embryonic development. However, the role of EphrinB2 in cardiac lymphangiogenesis following
Yingnan Bai +19 more
doaj +2 more sources
Lymphatic Endothelial Markers and Tumor Lymphangiogenesis Assessment in Human Breast Cancer
Diagnostics, 2021 Metastasis via lymphatic vessels or blood vessels is the leading cause of death for breast cancer, and lymphangiogenesis and angiogenesis are critical prerequisites for the tumor invasion–metastasis cascade.
Jia-Mei Chen +5 more
doaj +1 more source
Nature Communications, 2021 Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with a poor prognosis. Here the authors report the characterization of a human IBC cell line recapitulating the clinical and histopathological features of the human disease, and ...
Anita Rogic +14 more
doaj +1 more source
Lymphangiogenesis and Cancer [PDF]
Genes & Cancer, 2011 Historically, lymphatic vessels were considered passive participants in tumor metastasis by simply providing channels for tumor cells to transit to draining lymph nodes. The discovery of several key lymphatic-specific molecular markers and an increased availability of in vitro and in vivo experimental systems to study lymphatic biology have however ...
Christiansen A, Detmar M
openaire +3 more sources
Activation of Dll4/Notch Signaling and Hypoxia-Inducible Factor-1 Alpha Facilitates Lymphangiogenesis in Lacrimal Glands in Dry Eye. [PDF]
PLoS ONE, 2016 By using hypoxia-inducible factor-1 alpha conditional knockout (HIF-1α CKO) mice and a dry eye (DE) mouse model, we aimed to determine the role played by delta-like ligand 4 (Dll4)/Notch signaling and HIF-1α in the lymphangiogenesis of lacrimal glands ...
Ji Hwan Min +7 more
doaj +1 more source
Lymphangiogenesis and Anti-lymphangiogenesis in Cutaneous Melanoma [PDF]
Anticancer Research, 2016 Cutaneous malignant melanoma is an aggressive tumor characterized by early lymph node metastasis and bad prognosis. Although the spread of tumor cells in the regional lymph nodes is very important in the staging, prognosis and therapeutic strategy of malignant melanoma, the mechanism(s) of initial lymphatic vessels invasion is are) not completely ...
Marius, Raica +2 more
openaire +2 more sources