Results 1 to 10 of about 26,475 (231)

EphrinB2-mediated CDK5/ISL1 pathway enhances cardiac lymphangiogenesis and alleviates ischemic injury by resolving post-MI inflammation

Signal Transduction and Targeted Therapy
EphrinB2 (erythropoietin-producing hepatoma interactor B2) is a key Eph/ephrin family member, promoting angiogenesis, vasculogenesis, and lymphangiogenesis during embryonic development. However, the role of EphrinB2 in cardiac lymphangiogenesis following
, Chen Xueying, Wang Shijun
exaly   +3 more sources

Lymphangiogenesis in gastric cancer: function and mechanism

European Journal of Medical Research, 2023
Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's poor prognosis.
Pengpeng Liu, Ping’an Ding, Chenyu Sun, Shuya Chen, Scott Lowe, Lingjiao Meng, Qun Zhao   +6 more
doaj   +2 more sources

Exosomal circ_0026611 contributes to lymphangiogenesis by reducing PROX1 acetylation and ubiquitination in human lymphatic endothelial cells (HLECs)

Cellular & Molecular Biology Letters, 2023
Background Esophageal squamous carcinoma (ESCC) is a common malignancy that originates in the digestive tract. Lymph node metastasis (LNM) is a complicated process, and tumor lymphangiogenesis has been reported to be associated with the spread of tumor ...
Wenjian Yao, Xiangbo Jia, Li Zhu, Lei Xu, Quan Zhang, Tian Xia, Li Wei   +6 more
doaj   +2 more sources

ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer

Advanced Science, 2023
As a key step of tumor lymphatic metastasis, lymphangiogenesis is regulated by VEGFC‐VEGFR3 signaling pathway mediated by immune cells, mainly macrophages, in the tumor microenvironment.
Qiang Zhang, Sen Liu, Hongjin Wang, Kanghua Xiao, Junlin Lu, Siting Chen, Ming Huang, Ruihui Xie, Tianxin Lin, Xu Chen   +9 more
doaj   +2 more sources

Reactive Oxygen Species in Regulating Lymphangiogenesis and Lymphatic Function

Cells, 2022
The lymphatic system is pivotal for immunosurveillance and the maintenance of tissue homeostasis. Lymphangiogenesis, the formation of new lymphatic vessels from pre-existing vessels, has both physiological and pathological roles.
Bhupesh Singla, Ravi Varma Aithabathula, Sonia Kiran, Shweta Kapil, Santosh Kumar, Udai P. Singh   +5 more
doaj   +2 more sources

Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells

Nature Communications, 2019
There are no conventional lymphatic vessels within the CNS parenchyma, although it has been hypothesized that lymphatics near the cribriform plate or dura maintain fluid homeostasis and immune surveillance during steady-state conditions.
Sarah Marcus, Aditya Rayasam, Zsuzsanna Fabry   +2 more
exaly   +2 more sources

Effects of adenosine on lymphangiogenesis. [PDF]

PLoS ONE, 2014
BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood but promotes tumor spread and metastasis during ...
Bénédicte Lenoir, Daniel R Wagner, Silvia Blacher, Graciela B Sala-Newby, Andrew C Newby, Agnès Noel, Yvan Devaux   +6 more
doaj   +5 more sources

Lymphatics and Lymphangiogenesis in the Eye [PDF]

Journal of Ophthalmology, 2012
Lymphatic is a prerequisite for the maintenance of tissue fluid balance and immunity in the body. A body of evidence also shows that lymphangiogenesis plays important roles in the pathogenesis of diseases such as tumor metastasis and inflammation.
Shintaro Nakao, Ali Hafezi-Moghadam, Tatsuro Ishibashi   +2 more
doaj   +5 more sources

Lymphangiogenesis and cancer metastasis [PDF]

Journal of Cellular and Molecular Medicine, 2009
Abstract Anatomy and function of the lymphatic system Tumour‐induced lymphangiogenesis promotes metastasis Tumour‐induced lymph node lymphangiogenesis precedes cancer metastasis to lymph nodes Tumour cell invasion into lymphatic vessels Peri‐ and intra‐tumoral lymphangiogenesis Lymphatic vessel markers and lymphangiogenic growth factors Preventive and ...
Mumprecht V, Detmar M
exaly   +4 more sources

Lymphatic Endothelial Cells and Organ-Associated Lymphangiogenesis in Tumor Microenvironment [PDF]

Cells
Lymphatic vessels are a kind of heterogeneous and versatile component of the lymphatic system, with a unique ability to respond to environmental changes in different organs.
Rui-Cheng Ji
doaj   +2 more sources