Results 41 to 50 of about 26,475 (231)
Cell Death and Disease, 2021 Inflammation plays a crucial role in the occurrence and development of renal fibrosis, which ultimately results in end-stage renal disease (ESRD). There is new focus on lymphangiogenesis in the field of inflammation.
Ying Zhang +11 more
semanticscholar +1 more source
Molecular Therapy, 2021 Lymphatic metastasis constitutes a leading cause of recurrence and mortality in bladder cancer. Accumulating evidence indicates that lymphangiogenesis is indispensable to trigger lymphatic metastasis. However, the specific mechanism is poorly understood.
Jiang Zhu +11 more
semanticscholar +1 more source
Promoting inflammatory lymphangiogenesis by vascular endothelial growth factor-C (VEGF-C) aggravated intestinal inflammation in mice with experimental acute colitis [PDF]
Brazilian Journal of Medical and Biological Research, 2016 Angiogenesis and lymphangiogenesis are thought to play a role in the pathogenesis of inflammatory bowel diseases (IBD). However, it is not understood if inflammatory lymphangiogenesis is a pathological consequence or a productive attempt to resolve the ...
X.L. Wang, J. Zhao, L. Qin, M. Qiao
doaj +3 more sources
Cell Reports, 2019 Summary: Lymphatic vascular development establishes embryonic and adult tissue fluid balance and is integral in disease. In diverse vertebrate organs, lymphatic vessels display organotypic function and develop in an organ-specific manner. In all settings,
Adam J. Vogrin +9 more
doaj +1 more source
Molecular Cancer, 2020 Patients with lymph node (LN)-positive pancreatic ductal adenocarcinoma (PDAC) have extremely poor survival rates. Circular RNAs (circRNAs), a newly discovered type of endogenous noncoding RNAs, have been proposed to mediate the progression of diverse ...
Yao Kong +9 more
semanticscholar +1 more source
Circulation, 2012 At the level of the capillaries, the systemic circulation loses about 2-4 liters of fluid and about 100g of protein into the interstitium daily. This ultrafiltrate of the systemic capillaries is returned to the circulatory system by the lymphatics. The lymphatic vasculature is highly specialized to perform this service, beginning with the blind-ended ...
openaire +3 more sources
Clinical and Translational Medicine, 2021 Prolonged pressure overload triggers cardiac hypertrophy and frequently leads to heart failure (HF). Vascular endothelial growth factor‐C (VEGF‐C) and its receptor VEGFR‐3 are components of the central pathway for lymphatic vessel growth (also known as ...
Qiu-Yue Lin +4 more
semanticscholar +1 more source
Arteriosclerosis, Thrombosis and Vascular Biology, 2022 Lymphatic vessels are low-pressure, blind-ended tubular structures that play a crucial role in the maintenance of tissue fluid homeostasis, immune cell trafficking, and dietary lipid uptake and transport.
Xiaolei Liu +13 more
semanticscholar +1 more source
Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas
Science Advances, 2021 New approach for immune cell recruitment in therapeutic anticancer vaccines drives antigenically broad and long-lasting immunity. In melanoma, the induction of lymphatic growth (lymphangiogenesis) has long been correlated with metastasis and poor ...
M. Sasso +7 more
semanticscholar +1 more source
Kuoxin Decoction promotes lymphangiogenesis in zebrafish and in vitro based on network analysis
Frontiers in Pharmacology, 2022 Background: Inadequate lymphangiogenesis is closely related to the occurrence of many kinds of diseases, and one of the important treatments is to promote lymphangiogenesis.
Longping Peng +13 more
doaj +1 more source