Results 41 to 50 of about 33,655 (235)

Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]

, 2014
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise, Chuva de Sousa Lopes, Susana Marina, de Koning, Eelco JP, de Melo Bernardo, Ana, Mummery, Christine L, Roost, Matthias S, van Iperen, Liesbeth   +6 more
core   +1 more source

Lymphangiogenesis and cancer metastasis [PDF]

Journal of Cellular and Molecular Medicine, 2009
Abstract Anatomy and function of the lymphatic system Tumour‐induced lymphangiogenesis promotes metastasis Tumour‐induced lymph node lymphangiogenesis precedes cancer metastasis to lymph nodes Tumour cell invasion into lymphatic vessels Peri‐ and intra‐tumoral lymphangiogenesis Lymphatic vessel markers and lymphangiogenic growth factors Preventive and ...
Mumprecht, Viviane, Detmar, Michael
openaire   +2 more sources

A zebrafish model of inflammatory lymphangiogenesis

Biology Open, 2015
Inflammatory bowel disease (IBD) is a disabling chronic inflammatory disease of the gastrointestinal tract. IBD patients have increased intestinal lymphatic vessel density and recent studies have shown that this may contribute to the resolution of IBD ...
Kazuhide S. Okuda, June Pauline Misa, Stefan H. Oehlers, Christopher J. Hall, Felix Ellett, Sultan Alasmari, Graham J. Lieschke, Kathryn E. Crosier, Philip S. Crosier, Jonathan W. Astin   +9 more
doaj   +1 more source

Effects of inhibition of lymphangiogenesis by the vascular endothelial growth factor receptor 3 (VEGFR-3) inhibitor, MAZ51 on full thickness wounds in mice

Veins and Lymphatics, 2021
We herein used MAZ51 to inhibit lymphangiogenesis and aimed to clarify the effect of inhibition of lymphangiogenesis on wound healing. BALB/c male mice were divided into two groups: the control group which was injected the dimethyl sulfoxide (DMSO), the ...
Kana Takada, Yukari Nakajima, Tamae Urai, Kanae Mukai, Kimi Asano, Mayumi Okuwa, Junko Sugama, Toshio Nakatani   +7 more
doaj   +1 more source

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers. [PDF]

, 2016
mTOR inhibition has emerged as a promising strategy for head and neck squamous cell carcinomas (HNSCC) treatment. However, most targeted therapies ultimately develop resistance due to the activation of adaptive survival signaling mechanisms limiting the ...
Amornphimoltham, Panomwat, Califano, Joseph A, Callejas-Valera, Juan Luis, Cohen, Ezra E, Gutkind, J Silvio, Iglesias-Bartolomé, Ramiro, Lippman, Scott M, Luo, Ji, Molinolo, Alfredo A, Wang, Zhiyong, Yamaguchi, Kosuke   +10 more
core   +1 more source

Growth Hormone Promotes Lymphangiogenesis [PDF]

The American Journal of Pathology, 2008
The lymphatic system plays an important role in inflammation and cancer progression, although the molecular mechanisms involved are poorly understood. As determined using comparative transcriptional profiling studies of cultured lymphatic endothelial cells versus blood vascular endothelial cells, growth hormone receptor was expressed at much higher ...
Nadja Erika, Banziger-Tobler, Cornelia, Halin, Kentaro, Kajiya, Michael, Detmar   +3 more
openaire   +2 more sources

CEACAM1 increased the lymphangiogenesis through miR-423-5p and NF- kB in Non-Small Cell Lung Cancer

Biochemistry and Biophysics Reports
Background: Lung cancer causes significant mortality, with invasion and metastasis being the main features that cause most cancer deaths. Lymph node metastasis is the primary metastatic route in non-small cell carcinoma (NSCLC) and influences the staging
Jie Yu, Wenke Cai, Tao Zhou, Bo Men, Shunqiong Chen, Dong Tu, Wei Guo, Jicui Wang, Feipeng Zhao, Yan Wang   +9 more
doaj   +1 more source

Dye diffusion during laparoscopic tubal patency tests may suggest a lymphatic contribution to dissemination in endometriosis: A prospective, observational study [PDF]

, 2019
Aim Women with adenomyosis are at higher risk of endometriosis recurrence after surgery. This study was to assess if the lymphatic vessel network drained from the uterus to near organs where endometriosis foci lied.
Bonaccorsi, G., Greco, P., Noventa, M., Pesci, A., Scardapane, A., Scioscia, M., Zamboni, G.   +6 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Effects of adenosine on lymphangiogenesis. [PDF]

PLoS ONE, 2014
BACKGROUND: The lymphatic system controls tissue homeostasis by draining protein-rich lymph to the vascular system. Lymphangiogenesis, the formation of lymphatic vessels, is a normal event in childhood but promotes tumor spread and metastasis during ...
Bénédicte Lenoir, Daniel R Wagner, Silvia Blacher, Graciela B Sala-Newby, Andrew C Newby, Agnès Noel, Yvan Devaux   +6 more
doaj   +1 more source