Results 31 to 40 of about 24,249 (204)
Lymphatic vascular morphogenesis in development, physiology, and disease [PDF]
, 2011 The lymphatic vasculature constitutes a highly specialized part of the vascular system that is essential for the maintenance of interstitial fluid balance, uptake of dietary fat, and immune response. Recently, there has been an increased awareness of the
Amélie Sabine +6 more
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Stimulation and Inhibition of Lymphangiogenesis Via Adeno-Associated Viral Gene Delivery [PDF]
, 2018 The lymphatic vessels can be selectively stimulated to grow in adult mice, rats and pigs by application of viral vectors expressing the lymphangiogenic factors VEGF-C or VEGF-D.
Karaman, Sinem +7 more
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Tumor-Derived Exosomal piR-hsa-28212 Promotes Lymphatic Metastasis in Breast Cancer. [PDF]
Cancer SciBreast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Wang Y +7 more
europepmc +2 more sources
Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases [PDF]
, 2016 International audienceAbstractBackgroundLymphatic metastasis is one of the leading causes of death in patients with different types of cancer and is the main prognostic factor for the disease survival.
Silvia Blacher +13 more
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Cellular & Molecular Biology Letters, 2023 Background Esophageal squamous carcinoma (ESCC) is a common malignancy that originates in the digestive tract. Lymph node metastasis (LNM) is a complicated process, and tumor lymphangiogenesis has been reported to be associated with the spread of tumor ...
Wenjian Yao +6 more
doaj +1 more source
Circulation, 2012 At the level of the capillaries, the systemic circulation loses about 2-4 liters of fluid and about 100g of protein into the interstitium daily. This ultrafiltrate of the systemic capillaries is returned to the circulatory system by the lymphatics. The lymphatic vasculature is highly specialized to perform this service, beginning with the blind-ended ...
openaire +3 more sources
Kuoxin Decoction promotes lymphangiogenesis in zebrafish and in vitro based on network analysis
Frontiers in Pharmacology, 2022 Background: Inadequate lymphangiogenesis is closely related to the occurrence of many kinds of diseases, and one of the important treatments is to promote lymphangiogenesis.
Longping Peng +13 more
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Myeloid Cells and Lymphangiogenesis [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 The lymphatic vascular system and the hematopoietic system are intimately connected in ontogeny and in physiology. During embryonic development, mammalian species derive a first lymphatic vascular plexus from the previously formed anterior cardinal vein, whereas birds and amphibians have a lymphatic vascular system of dual origin, composed of lymphatic
Zumsteg, Adrian, Christofori, Gerhard
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Chinese Journal of Lung Cancer, 2021 Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
doaj +1 more source
前立腺癌患者における術前内分泌療法によるリンパ管新生とVEGF（vascular endothelial growth factor）発現の変化 [PDF]
, 2017 BACKGROUND: The anti-cancer mechanism of neo-adjuvant hormonal therapy (NHT) is not well understood. Lymphangiogenesis plays an important role in cancer progression and is regulated by a complex mechanism that includes vascular endothelial growth factor (
浅井, 昭宏
core +1 more source