Results 51 to 60 of about 26,475 (231)

The Effect of Lymphangiogenesis in Transplant Arteriosclerosis

Circulation, 2022
Background: Transplant arteriosclerosis is a major complication in long-term survivors of heart transplantation. Increased lymph flow from donor heart to host lymph nodes has been reported to play a role in transplant arteriosclerosis, but how ...
Kai Chen, Rong Mou, Pengwei Zhu, Xiaodong Xu, Han Wang, Liujun Jiang, Yanhua Hu, Xiaosheng Hu, Liang Ma, Q. Xiao, Qingbo Xu   +10 more
semanticscholar   +1 more source

Progress in the Mechanism of Lymphangiogenesis and Lymphatic Metastasis 
of Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2021
Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
doaj   +1 more source

Myeloid Cells and Lymphangiogenesis [PDF]

Cold Spring Harbor Perspectives in Medicine, 2012
The lymphatic vascular system and the hematopoietic system are intimately connected in ontogeny and in physiology. During embryonic development, mammalian species derive a first lymphatic vascular plexus from the previously formed anterior cardinal vein, whereas birds and amphibians have a lymphatic vascular system of dual origin, composed of lymphatic
Zumsteg, Adrian, Christofori, Gerhard
openaire   +4 more sources

Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis

International Journal of Cell Biology, 2012
In the 1970s, the late Judah Folkman postulated that tumors grow proportionately to their blood supply and that tumor angiogenesis removed this limitation promoting growth and metastasis. Work over the past 40 years, varying from molecular examination to
Jie Chen, J. Steven Alexander, A. Wayne Orr   +2 more
doaj   +1 more source

Lymphangiogenesis Guidance Mechanisms and Therapeutic Implications in Pathological States of the Cornea

Cells, 2023
Corneal lymphangiogenesis is one component of the neovascularization observed in several inflammatory pathologies of the cornea including dry eye disease and corneal graft rejection.
Mehul Patnam, Sunil R. Dommaraju, Faisal Masood, Paula Herbst, Jin-Hong Chang, Wen-Yang Hu, Mark I. Rosenblatt, Dimitri T. Azar   +7 more
doaj   +1 more source

Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure

bioRxiv, 2021
Rationale Lymphatics are essential for cardiac health, and insufficient lymphatic expansion (lymphangiogenesis) contributes to development of heart failure (HF) after myocardial infarction. However, the regulation and impact of lymphatics in non-ischemic
C. Heron, A. Dumesnil, Mahmoud Houssari, S. Renet, T. Lemarcis, A. Lebon, David Godefroy, Damien Schapman, O. Henri, Gaetan Riou, L. Nicol, J. Henry, M. Valet, M. Pieronne-Deperrois, A. Ouvrard-Pascaud, Réné Hagerling, H. Chiavelli, J. Michel, P. Mulder, S. Fraineau, V. Richard, V. Tardif, E. Brakenhielm   +22 more
semanticscholar   +1 more source

Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation

iScience
Summary: Lymphatic vessels are required for the clearance of excess fluid and immune cells from inflamed tissue, making the regulation of lymphangiogenesis an important area of research.
Daisuke Katoh, Yoshiyuki Senga, Kento Mizutani, Kazuaki Maruyama, Daishi Yamakawa, Tadashi Yamamuro, Michiaki Hiroe, Keiichi Yamanaka, Akihiro Sudo, Naoyuki Katayama, Toshimichi Yoshida, Kyoko Imanaka-Yoshida   +11 more
doaj   +1 more source

Effects of inhibition of lymphangiogenesis by the vascular endothelial growth factor receptor 3 (VEGFR-3) inhibitor, MAZ51 on full thickness wounds in mice

Veins and Lymphatics, 2021
We herein used MAZ51 to inhibit lymphangiogenesis and aimed to clarify the effect of inhibition of lymphangiogenesis on wound healing. BALB/c male mice were divided into two groups: the control group which was injected the dimethyl sulfoxide (DMSO), the ...
Kana Takada, Yukari Nakajima, Tamae Urai, Kanae Mukai, Kimi Asano, Mayumi Okuwa, Junko Sugama, Toshio Nakatani   +7 more
doaj   +1 more source

Lymphangiogenesis: novel strategies to promote cutaneous wound healing

Burns & Trauma
The cutaneous lymphatic system regulates tissue inflammation, fluid balance and immunological responses. Lymphangiogenesis or lymphatic dysfunction may lead to lymphedema, immune deficiency, chronic inflammation etc.
Yang Jian, Yanqi Li, Yanji Zhang, M. Tang, Mingfu Deng, Chenxiaoxiao Liu, Maolin Cheng, Shune Xiao, Chengliang Deng, Zairong Wei   +9 more
semanticscholar   +1 more source

ADSCs enhance VEGFR3-mediated lymphangiogenesis via METTL3-mediated VEGF-C m6A modification to improve wound healing of diabetic foot ulcers

Molecular Medicine, 2021
Adipose-derived mesenchymal stem cells (ADSCs) are an important focus in regenerative medicine. However, the biological function of ADSCs in the wound repair of diabetic foot ulcers (DFUs) remains unclear.
Jie Zhou, Tianhong Wei, Zhiyou He
semanticscholar   +1 more source