Results 111 to 120 of about 119,650 (284)

The Lymphatic System in Health and Disease [PDF]

, 1940
Leah Cueni, Michael Detmar, G Asellius, P Baluk, J Fuxe, H Hashizume, T Romano, E Lashnits, S Butz, D Vestweber, M Corada, C Molendini, E Dejana, D Mc-Donald, F Sabin, G Huntington, Cfw Mcclure, J Wigle, N Harvey, M Detmar, I Lagutina, G Grosveld, M Gunn, D Jackson, G Oliver, J Wigle, G Oliver, G Oliver, B Sosa-Pineda, S Geisendorf, E Spana, C Doe, P Gruss, R Srinivasan, M Dillard, O Lagutin, F Lin, S Tsai, M Tsai, I Samokhvalov, G Oliver, K Yaniv, S Isogai, D Castranova, L Dye, J Hitomi, B Weinstein, A Ny, M Koch, M Schneider, E Neven, R Tong, S Maity, C Fischer, S Plaisance, D Lambrechts, C Heligon, S Terclavers, M Ciesiolka, R Kalin, W Man, I Senn, S Wyns, F Lupu, A Brandli, K Vleminckx, Collen Dewerchin, M Conway, E Moons, L Jain, R Carmeliet, P, M Schneider, K Othman-Hassan, B Christ, J Wilting, J Wilting, Y Aref, R Huang, S Tomarev, L Schweigerer, B Christ, P Valasek, M Papoutsi, J Kreuger, I Nilsson, D Kerjaschki, T Petrova, K Alitalo, Claesson- Welsh, L, R Liersch, F Nay, L Lu, M Detmar, K Buttler, A Kreysing, Von Kaisenberg, C Schweigerer, L Gale   +99 more
openalex   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

Advanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias, Maxwell J. Munford, Frederik C.H. Masure, Richard J. van Arkel, Reece N Oosterbeek   +4 more
wiley   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

Advanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei, Luping Wang, Haitong Jing, Xian Qin, Jiong‐Wei Wang, Xiaogang Liu   +5 more
wiley   +1 more source

Lymphatic-immune interactions in the musculoskeletal system

Frontiers in Immunology
Traditionally, the role of lymphatic vessels has been understood as primarily involving fluid transport and immune surveillance. In addition to these roles, recent studies have revealed a paracrine function of lymphatics through the dissemination of ...
Hanyu Liu, Lu Liu, Yuheng Zhang, Qi Tian, Zhangfan Ding, Zhangfan Ding, Junyu Chen, Junyu Chen, Anjali P. Kusumbe, Anjali P. Kusumbe   +9 more
doaj   +1 more source

Expanded phenotypic spectrum of JAG1 ‐associated diseases: Central conducting lymphatic anomaly with a pathogenic variant in JAG1

, 2021
Dong Li, Sarah E. Sheppard, Christina Peroutka, Caitlin Barnes, Janet R. Reid, Christopher L. Smith, Yoav Dori, Håkon Håkonarson   +7 more
openalex   +2 more sources

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Lymphatic vessel: Origin, heterogeneity, biological functions and therapeutic targets

Signal Transduction and Targeted Therapy
Lymphatic vessels, comprising the secondary circulatory system in human body, play a multifaceted role in maintaining homeostasis among various tissues and organs.
Zhaoliang Hu, Xushi Zhao, Zhonghua Wu, Bicheng Qu, Minxian Yuan, Yanan Xing, Yongxi Song, Zhenning Wang   +7 more
doaj   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source