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Physiological Reviews, 2022
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph nodes that are present in almost every tissue of the human body, acts as an essential transport system for fluids, biomolecules and cells between peripheral ...
L. Dieterich+3 more
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The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph nodes that are present in almost every tissue of the human body, acts as an essential transport system for fluids, biomolecules and cells between peripheral ...
L. Dieterich+3 more
semanticscholar +1 more source
2000
The diseases of the lymphatics appear almost exclusively on the legs. Only occasionally are the arms, trunk and even head involved. The visual evidence of lymphatic disease is lymphedema, an edema or swelling that is the result of impaired lymphatic return.
Walter H.C. Burgdorf+3 more
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The diseases of the lymphatics appear almost exclusively on the legs. Only occasionally are the arms, trunk and even head involved. The visual evidence of lymphatic disease is lymphedema, an edema or swelling that is the result of impaired lymphatic return.
Walter H.C. Burgdorf+3 more
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Advances in Diagnosis of Diseases of the Lymphatics
JAMA: The Journal of the American Medical Association, 1962Radiographic delineation of peripheral lymphatic vessels and of lymph nodes has aided in the specific diagnosis of regional edema and lymphatic neoplasms. Whereas anatomic abnormalities in lymphatic vessels are an infrequent finding in all types of primary venous disease, patients with primary lymphedema have shown dilatation, tortuosity, fragmentation,
C. Danese+3 more
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Biological functions of lymphatic vessels
Science, 2020Roles of organ-specific lymphatic vessels Lymphatic vessels are spread throughout the human body and have critical functions in mammalian physiology. Petrova et al.
T. Petrova, G. Koh
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Advances in Materials, 2021
Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages of protecting against hepatic first‐pass metabolism of the drug and improving its pharmacokinetic performance.
Yang‐Bao Miao+9 more
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Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages of protecting against hepatic first‐pass metabolism of the drug and improving its pharmacokinetic performance.
Yang‐Bao Miao+9 more
semanticscholar +1 more source
The lymphatic vasculature in disease
Nature Medicine, 2011Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic vessels is to collect excess protein-rich fluid that has extravasated from blood vessels and transport it back into the blood circulation.
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Lymphatic Vasculature: An Emerging Therapeutic Target and Drug Delivery Route.
Annual Review of Medicine, 2021The lymphatic system has received increasing scientific and clinical attention because a wide variety of diseases are linked to lymphatic pathologies and because the lymphatic system serves as an ideal conduit for drug delivery.
Wenjing Xu, Natalie R Harris, K. Caron
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Comorbidity and Lymphatic Disease: The Lymphatic Continuum Re-Examined
Lymphatic Research and Biology, 2021It has now been ∼20 years since the original Lymphatic Continuum conference was convened, and this continuum has transitioned from a compelling concept to a reality. The explosive growth in our comprehension of lymphatic genetics, development, and function has expanded and modified our traditional views regarding what is, and is not, lymphatic disease.
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The Clinical Spectrum of Lymphatic Disease
Annals of the New York Academy of Sciences, 2008Lymphatic disease is quite prevalent, and often not well clinically characterized. Beyond lymphedema, there is a broad array of human disease that directly or indirectly alters lymphatic structure and function. The symptomatic and objective presentation of these patients can be quite diverse.
Stanley G. Rockson, Kavita Radhakrishnan
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Therapeutic Delivery to the Brain via the Lymphatic Vasculature.
Nano letters (Print), 2020Targeted delivery of therapeutics to disease sites has been one of the biggest challenges in medicine as it determines treatment efficacy of virtually all chemical and biological drugs. Furthermore, it is particularly difficult to achieve for diseases in
Pengfei Zhao+3 more
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