Results 51 to 60 of about 14,696 (273)

An Unusual Presentation of a Lymphatic Malformation in an Adult: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2022
Introduction: Patients commonly present with neck masses to the Emergency Department. The acute presentation of such a mass can be alarming to patients and their families. In this report we discuss a rare etiology of an acutely presenting neck mass in an
Marguerite Gilmore, Sharon H. Kim, Christopher M. McDowell   +2 more
doaj   +1 more source

Pregnancy-associated breast cancer - Special features in diagnosis and treatment [PDF]

, 2006
For obvious psychological reasons it is difficult to associate pregnancy - a life-giving period of our existence with life-threatening malignancies. Symptoms pointing to malignancy are often ignored by both patients and physicians, and this, together ...
Bauerfeind, I., Dian, D., Friese, K., Gerber, B., Janni, W., Krause, A., Rack, B., Sommer, H.   +7 more
core   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Infected cystic hygroma resulting in septic shock and respiratory failure: A case report

Journal of Pediatric Surgery Case Reports, 2016
Macrocystic lymphatic malformations (cystic hygromas) are a common cause of cystic neck lesions. These lesions are often diagnosed prenatally in children.
Maria E. Linnaus, David M. Notrica
doaj   +1 more source

Congenital vascular malformations update [PDF]

, 2014
Presently, there is controversy and misconception in the diagnosis and management of most congenital vascular malformations. The aim of this manuscript is to identify the current knowledge of these poorly understood and relatively uncommon pathologies ...
Albores Figueroa, Rosemberg, Gómez Danés, Luis Humberto, Hernández Sánchez, Marely, Montes Tapia, Fernando Félix, Rendón Elías, Felipe   +4 more
core  

Clinical delineation and natural history of the PIK3CA-related overgrowth spectrum. [PDF]

, 2014
Somatic mutations in the phosphatidylinositol/AKT/mTOR pathway cause segmental overgrowth disorders. Diagnostic descriptors associated with PIK3CA mutations include fibroadipose overgrowth (FAO), Hemihyperplasia multiple Lipomatosis (HHML), Congenital ...
Balasubramanian, M., Biesecker, L.G., Blumhorst, C., Braverman, N., Brennan, L.M., Chandler, K.E., Clark, R., Crow, Y.J., Cunningham, M.L., Darling, T., Fraser, J.L., Geer, J., Graham, J.M., Grant, I., Gucev, Z., Henderson, A., Huson, S.M., Jakkula, E., Keppler-Noreuil, K.M., Krishnamurty, V., Lindhurst, M.J., Parker, V.E., Pena, L.D., Sapp, J.C., Sellars, E.A., Semple, R.K., Shuen, A., Sutton, V.R., Tasic, V., Tosi, L.L., Whitehouse, R.W.   +30 more
core   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, EarlyView.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Net‐like superficial lymphatic malformation

Pediatric Dermatology, 2021
AbstractThe net‐like superficial lymphatic malformation (LM) is a newly described entity with distinctive clinical, dermoscopic, and histologic characteristics. Clinical picture consists of red to purplish macules with a finely reticulated pattern of vascular structures. Dermoscopy shows arborizing telangiectatic vessels.
Helena Iznardo, Eulalia Baselga, Anna Mozos, Justyna Szafranska, Ruth Orellana‐Fernández, Esther Roé   +5 more
openaire   +5 more sources

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J, Kato, Shumei, Kurzrock, Razelle, Lippman, Scott M   +3 more
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source