Results 301 to 310 of about 709,350 (366)

Potential functions and mechanisms of lysine crotonylation modification (Kcr) in tumorigenesis and lymphatic metastasis of papillary thyroid cancer (PTC). [PDF]

J Transl Med
Li Z, Li J, Li F, Han L, Sui C, Zhou L, Zhang D, Fu Y, Du R, Kou J, Dionigi G, Sun H, Liang N.   +12 more
europepmc   +1 more source

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

Advanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang, Yongjian Zhang, Yajuan Fu, Dangjin Ke, Qi Chen, Sijie Shao, Panpan Xue, Yuanchun Chen, Xuemei Zeng, Shuangqian Yan   +9 more
wiley   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

UBE2C-induced crosstalk between mono- and polyubiquitination of SNAT2 promotes lymphatic metastasis in bladder cancer. [PDF]

J Clin Invest
Li W, Chen C, Zheng H, Lin Y, An M, Liu D, Zhang Y, Gao M, Lan T, He W.   +9 more
europepmc   +1 more source

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients

, 2018
Hong Jun Kim, Min Jee Jo, Bo Ram Kim, Jung Lim Kim, Yoon A Jeong, Yoo Jin Na, Seong Hye Park, Suk‐young Lee, Dae‐Hee Lee, Baek‐hui Kim, Young Yoo, Sang Cheul Oh   +11 more
openalex   +2 more sources

KRAS mRNA Spleen‐Targeting Lipid Nanoparticles Synergize with Irinotecan Silicasomes to Robustly Augment the Cancer Immunity Cycle in Pancreatic Cancer

Advanced Science, EarlyView.
To overcome pancreatic cancer's immunosuppressive barriers, this study explores a dual approach: triggering immunogenic tumor cell death at the primary tumor site with irinotecan‐loaded silicasomes and enhancing immune activation in the spleen using LNPs encapsulating tumor antigen mRNA and a TLR7/8 agonist.
Lijia Luo, Xiang Wang, Yu‐Pei Liao, Andre E. Nel   +3 more
wiley   +1 more source

cGAS-ISG15-RAGE axis reprogram necroptotic microenvironment and promote lymphatic metastasis in head and neck cancer. [PDF]

Exp Hematol Oncol
Li J, Tan J, Wang T, Yu S, Guo G, Li K, Yang L, Zeng B, Mei X, Gao S, Lao X, Zhang S, Liao G, Liang Y.   +13 more
europepmc   +1 more source

Author response: Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation

, 2018
Pirita Pekkonen, Sanni Alve, Giuseppe Balistreri, Silvia Gramolelli, Olga Tatti-Bugaeva, Ilkka Paatero, Otso Niiranen, Krista Tuohinto, Nina Perälä, Adewale Taiwo, Nadezhda Zinovkina, Pauliina Repo, Katherine Icay, Johanna Ivaska, Pipsa Saharinen, Sampsa Hautaniemi, Kaisa Lehti, Päivi M. Ojala   +17 more
openalex   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

Advanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen, Qing Zhang, Jiajia Li, Xia Zhou, Daxing Gao, Lu Li, Dabing Huang, Jizhou Wang, Zhutian Zeng   +8 more
wiley   +1 more source

The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer. [PDF]

Int J Med Sci
Xu DM, Chen LX, Zhuang XY, Han H, Mo M.
europepmc   +1 more source