Results 311 to 320 of about 709,350 (366)

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

SUMOylation-Driven mRNA Circularization Enhances Translation and Promotes Lymphatic Metastasis of Bladder Cancer. [PDF]

Cancer Res
Zhao Y, Chen J, Zheng H, Luo Y, An M, Lin Y, Pang M, Li Y, Kong Y, He W, Lin T, Chen C.   +11 more
europepmc   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

Amplifying Anti‐Tumor Immune Responses via Mitochondria‐Targeting Near‐Infrared Photodynamic Therapy

Advanced Science, EarlyView.
Interfacial Nd3+‐triplet energy transfer enables direct activation of molecular triplets under near‐infrared (NIR) irradiation for reactive oxygen species (ROS) generation. Photodynamic therapy (PDT) exaggerates hypoxia, which initiates subsequent hypoxia‐activated chemotherapy.
Cheng‐Ao Li, Junjie Nan, Qingxuan Ye, Bingzhu Zheng, Xiaomeng Dai, Jingya Li, Feng Wang, Huimin Ma, Yu Cheng, Jian Ruan, Weijia Fang, Peng Zhao, Renren Deng, Dong Cen   +13 more
wiley   +1 more source

Correlation analysis of risk factors for cervical lymphatic metastasis in papillary thyroid carcinoma. [PDF]

Diagn Pathol
Sun H, Zhao X, Wang X, Ma J, Liu M.
europepmc   +1 more source

<p>High Tiam1 expression predicts positive lymphatic metastasis and worse survival in patients with malignant solid tumors: a systematic review and meta-analysis</p>

, 2019
Caixia Yang, Chenlin Ma, Yingchun Li, Mo Peng, Yusheng Yang   +4 more
openalex   +2 more sources

Radiomics‐Based Unsupervised Clustering Identifies Subtypes Associated With Prognosis and Immune Microenvironment in Clear Cell Renal Cell Carcinoma: A Multicenter Study

Advanced Science, EarlyView.
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo, Bingxin Gong, Yi Li, Jie Lou, Shuai Shan, Xiaodong Zhang, Qiang Lu, Dongyong Zhu, Qing Sun, Lianwei Miao, Yuanxi Li, Yu‐Dong Zhang, Wei Tan, Lian Yang, Chuansheng Zheng   +14 more
wiley   +1 more source

Screening high-risk individuals for primary gastric carcinoma: evaluating overall survival probability score in the presence and absence of lymphatic metastasis post-gastrectomy. [PDF]

World J Surg Oncol
Qu W, Li L, Ma J, Li Y.
europepmc   +1 more source

ROS‐Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling

Advanced Science, EarlyView.
In this study, ferroptosis in colorectal cancer cells is induced by FK866 through the NAD⁺/STAT3/GPX4 pathway. To minimize systemic toxicity, a reactive oxygen species (ROS)‐responsive hydrogel is developed to co‐deliver FK866 and C188‐9, resulting in synergistic and localized antitumor effects.
Chenyang Ye, Mi Mi, Saimeng Shi, Lina Qi, Shanshan Weng, Lu Wang, Yier Lu, Chao Chen, Yinuo Tan, Mengyuan Yang, Cheng Guo, Rui Bai, Xuefeng Fang, Ji Wang, Ying Yuan   +14 more
wiley   +1 more source